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Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.587-595

2005

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Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1313-1333

2001

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Pharmacokinetics and Metabolism in Drug Design

3rd, rev. and updated ed., 2012

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In Silico Modeling for the Nonlinear Absorption Kinetics of UK-343,664: A P-gp and CYP3A4 Substrate

Molecular pharmaceutics, 2012-03, Vol.9 (3), p.492-504

2012

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Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate

Birth defects research, 2018-04, Vol.110 (7), p.553-578

2018

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SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4471-4475

2009

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SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4471

2009

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Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1284-1287

2008

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Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1284-1287

2008

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Pharmacokinetics and Metabolism in Drug Design

2nd rev. ed., 2006

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Pharmacokinetics and metabolism in drug design, third, revised and updated edition, volume 51 (Methods and principles in medicinal chemistry)

3rd ed., 2012

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SAR of a series of inhaled A sub(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4471-4475

2009

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Inhaled adenosine A sub(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1284-1287

2008

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Inhaled adenosine A 2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (4), p.1284-1287

2008

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Metabolism, pharmacokinetics and toxicity of functional groups: impact of chemical building blocks on ADMET.

Smith, Dennis A

1, 2010

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Pharmacokinetics

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.19-40

2012

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Clearance

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.81-102

2012

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ADME Screening

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.229-250

2012

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Predicting Human Pharmacokinetics

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.209-227

2012

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Renal Clearance

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.103-110

2012

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Physicochemistry

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.1-17

2012

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Distribution

Pharmacokinetics and Metabolism in Drug Design, 2012, p.61-79

2012

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Toxicity

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.159-208

2012

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Absorption

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.41-59

2012

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Metabolic (Hepatic) Clearance

Pharmacokinetics and Metabolism in Drug Design, 2012, Vol.51, p.111-158

2012

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Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics

Pharmacokinetics and Metabolism in Drug Design

In Silico Modeling for the Nonlinear Absorption Kinetics of UK-343,664: A P-gp and CYP3A4 Substrate

Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate

SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Pharmacokinetics and Metabolism in Drug Design

Pharmacokinetics and metabolism in drug design, third, revised and updated edition, volume 51 (Methods and principles in medicinal chemistry)

SAR of a series of inhaled A sub(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Inhaled adenosine A sub(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Inhaled adenosine A 2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Metabolism, pharmacokinetics and toxicity of functional groups: impact of chemical building blocks on ADMET.

Pharmacokinetics

Clearance

ADME Screening

Predicting Human Pharmacokinetics

Renal Clearance

Physicochemistry

Distribution

Toxicity

Absorption

Metabolic (Hepatic) Clearance

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