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The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD

Frontiers in neuroscience, 2019-04, Vol.13, p.335

2019

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Neuroinflammation in schizophrenia: the role of nuclear factor kappa B

Translational psychiatry, 2021-10, Vol.11 (1), p.528-528, Article 528

2021

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NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

Neuropsychopharmacology (New York, N.Y.), 2013-08, Vol.38 (9), p.1609-1616

2013

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TDP-43 pathology: From noxious assembly to therapeutic removal

Progress in neurobiology, 2022-04, Vol.211, p.102229-102229, Article 102229

2022

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Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43

Acta neuropathologica, 2015-11, Vol.130 (5), p.643-660

2015

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ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation

PloS one, 2013-11, Vol.8 (11), p.e81170-e81170

2013

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Low dose aspirin blocks breast cancer-induced cognitive impairment in mice

PloS one, 2018-12, Vol.13 (12), p.e0208593-e0208593

2018

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Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD

Molecular psychiatry, 2023-06, Vol.28 (6), p.2445-2461

2023

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Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines

Journal of neuroinflammation, 2020-07, Vol.17 (1), p.215-215, Article 215

2020

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Mechanisms of chemotherapy-induced behavioral toxicities

Frontiers in neuroscience, 2015-04, Vol.9, p.131-131

2015

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Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study

BMC medicine, 2020-09, Vol.18 (1), p.238-12, Article 238

2020

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Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis

IUBMB life, 2011-09, Vol.63 (9), p.754-763

2011

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Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis

Human molecular genetics, 2015-07, Vol.24 (13), p.3830-3846

2015

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Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer

PloS one, 2023-11, Vol.18 (11), p.e0293905-e0293905

2023

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Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase

International journal of molecular sciences, 2024-01, Vol.25 (2), p.990

2024

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Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD

Frontiers in neuroscience, 2019-06, Vol.13, p.548-548

2019

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Impaired glymphatic function in the early stages of disease in a TDP-43 mouse model of amyotrophic lateral sclerosis

Translational neurodegeneration, 2022-03, Vol.11 (1), p.17-17, Article 17

2022

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miR-23a suppression accelerates functional decline in the rNLS8 mouse model of TDP-43 proteinopathy

Neurobiology of disease, 2022-01, Vol.162, p.105559-105559, Article 105559

2022

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Mutant SOD1 inhibits ER‐Golgi transport in amyotrophic lateral sclerosis

Journal of neurochemistry, 2014-04, Vol.129 (1), p.190-204

2014

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An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice

Human molecular genetics, 2015-12, Vol.24 (25), p.7241-7254

2015

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Astrocytic TDP-43 pathology in Alexander disease

The Journal of neuroscience, 2014-05, Vol.34 (19), p.6448-6458

2014

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Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Cellular and molecular life sciences : CMLS, 2018-01, Vol.75 (2), p.335-354

2018

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Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain

Acta neuropathologica communications, 2023-04, Vol.11 (1), p.69-69, Article 69

2023

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Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations

Molecular neurodegeneration, 2020-09, Vol.15 (1), p.1-51, Article 51

2020

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NSAID use and unnatural deaths after cancer diagnosis: a nationwide cohort study in Sweden

BMC cancer, 2022-01, Vol.22 (1), p.75-12, Article 75

2022

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The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD

Neuroinflammation in schizophrenia: the role of nuclear factor kappa B

NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

TDP-43 pathology: From noxious assembly to therapeutic removal

Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43

ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation

Low dose aspirin blocks breast cancer-induced cognitive impairment in mice

Early activation of cellular stress and death pathways caused by cytoplasmic TDP-43 in the rNLS8 mouse model of ALS and FTD

Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines

Mechanisms of chemotherapy-induced behavioral toxicities

Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study

Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis

Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer

Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase

Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD

Impaired glymphatic function in the early stages of disease in a TDP-43 mouse model of amyotrophic lateral sclerosis

miR-23a suppression accelerates functional decline in the rNLS8 mouse model of TDP-43 proteinopathy

Mutant SOD1 inhibits ER‐Golgi transport in amyotrophic lateral sclerosis

An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice

Astrocytic TDP-43 pathology in Alexander disease

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain

Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations

NSAID use and unnatural deaths after cancer diagnosis: a nationwide cohort study in Sweden

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