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Know thy cells: commonly used triple-negative human breast cancer cell lines carry mutations in RAS and effectors

Breast cancer research : BCR, 2022-06, Vol.24 (1), p.1-44, Article 44

Wagner, Kay-Uwe

2022

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

Nature communications, 2015-04, Vol.6 (1), p.6744-6744, Article 6744

2015

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Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents

Blood, 2017-03, Vol.129 (13), p.1823-1830

2017

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Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells

Stem cells (Dayton, Ohio), 2014-07, Vol.32 (7), p.1878-1889

2014

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Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells

Molecular and cellular endocrinology, 2017-08, Vol.451, p.31-39

2017

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Cellular Plasticity in Mammary Gland Development and Breast Cancer

Cancers, 2023-11, Vol.15 (23), p.5605

2023

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Estrogen receptor-α expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (37), p.14718-14723

2007

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Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

Nature communications, 2021-06, Vol.12 (1), p.3742-16, Article 3742

2021

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Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers

Cell reports (Cambridge), 2017-02, Vol.18 (9), p.2243-2255

2017

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Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis

Gut, 2017-01, Vol.66 (1), p.145-155

2017

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Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7–induced signaling

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (45), p.19455-19460

2010

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Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation

Reproductive biology and endocrinology, 2021-07, Vol.19 (1), p.112-112, Article 112

2021

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Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

Cell reports (Cambridge), 2018-11, Vol.25 (8), p.2192-2207.e5

2018

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Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

Hepatology (Baltimore, Md.), 2011-10, Vol.54 (4), p.1398-1409

2011

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Peripubertal requirement of Tsg101 in maintaining the integrity of membranous structures in mouse oocytes

Cell proliferation, 2022-10, Vol.55 (10), p.e13288-n/a

2022

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Exosomal microRNA in Pancreatic Cancer Diagnosis, Prognosis, and Treatment: From Bench to Bedside

Cancers, 2021-06, Vol.13 (11), p.2777

2021

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The Janus kinase 1 is critical for pancreatic cancer initiation and progression

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114202-114202, Article 114202

2024

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Dual recombinase action in the normal and neoplastic mammary gland epithelium

Scientific reports, 2021-10, Vol.11 (1), p.20775-20775, Article 20775

2021

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G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells

The Journal of biological chemistry, 2013-05, Vol.288 (19), p.13842-13849

2013

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Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

Scientific reports, 2017-08, Vol.7 (1), p.7653-15, Article 7653

2017

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The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease

Cancers, 2020-02, Vol.12 (2), p.450

2020

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Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy

Biology of the cell, 2016-11, Vol.108 (11), p.324-337

2016

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Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

Haematologica (Roma), 2014-04, Vol.99 (4), p.e52-e54

2014

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Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer

Cancer research (Chicago, Ill.), 2013-03, Vol.73 (6), p.1821-1830

2013

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Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans

PloS one, 2013-03, Vol.8 (3), p.e59675

2013

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Know thy cells: commonly used triple-negative human breast cancer cell lines carry mutations in RAS and effectors

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents

Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells

Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells

Cellular Plasticity in Mammary Gland Development and Breast Cancer

Estrogen receptor-α expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers

Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis

Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7–induced signaling

Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation

Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

Peripubertal requirement of Tsg101 in maintaining the integrity of membranous structures in mouse oocytes

Exosomal microRNA in Pancreatic Cancer Diagnosis, Prognosis, and Treatment: From Bench to Bedside

The Janus kinase 1 is critical for pancreatic cancer initiation and progression

Dual recombinase action in the normal and neoplastic mammary gland epithelium

G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease

Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy

Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans

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