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Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine‐linked antibody drug conjugate

Protein science, 2015-08, Vol.24 (8), p.1210-1223

2015

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Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies

Journal of mass spectrometry., 2015-02, Vol.50 (2), p.285-297

2015

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Characterization of Therapeutic Antibodies and Related Products

Analytical chemistry (Washington), 2013-01, Vol.85 (2), p.715-736

2013

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Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2855

2023

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Innovative Native MS Methodologies for Antibody Drug Conjugate Characterization: High Resolution Native MS and IM-MS for Average DAR and DAR Distribution Assessment

Analytical chemistry (Washington), 2014-11, Vol.86 (21), p.10674-10683

2014

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Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation

Talanta (Oxford), 2018-02, Vol.178, p.530-537

2018

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Protocols for the analytical characterization of therapeutic monoclonal antibodies. I – Non-denaturing chromatographic techniques

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-07, Vol.1058, p.73-84

2017

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Development of a fast workflow to screen the charge variants of therapeutic antibodies

Journal of Chromatography A, 2017-05, Vol.1498, p.147-154

2017

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Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry techniques

mAbs, 2013-09, Vol.5 (5), p.699-710

2013

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Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

Analytical biochemistry, 2009-09, Vol.392 (2), p.145-154

2009

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A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress

Biochemical journal, 2002-09, Vol.366 (Pt 3), p.777-785

2002

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The Brown Algal Kelp Laminaria digitata Features Distinct Bromoperoxidase and Iodoperoxidase Activities

The Journal of biological chemistry, 2003-06, Vol.278 (26), p.23545-23552

2003

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Vanadium-dependent iodoperoxidases in Laminaria digitata, a novel biochemical function diverging from brown algal bromoperoxidases

Journal of biological inorganic chemistry, 2005-03, Vol.10 (2), p.156-166

2005

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Adsorption and recovery issues of recombinant monoclonal antibodies in reversed-phase liquid chromatography

Journal of separation science, 2015-01, Vol.38 (1), p.1-8

2015

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Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities

Journal of pharmaceutical and biomedical analysis, 2020-05, Vol.184, p.113166, Article 113166

2020

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The way forward, enhanced characterization of therapeutic antibody glycosylation: Comparison of three level mass spectrometry-based strategies

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-09, Vol.872 (1), p.23-37

2008

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Use of PASEF for Accelerated Protein Sequence Confirmation and De Novo Sequencing with High Data Quality

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2313, p.207

2022

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Full validation of therapeutic antibody sequences by middle-up mass measurements and middle-down protein sequencing

mAbs, 2016-01, Vol.8 (2), p.318-330

2016

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Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies

Analytical chemistry (Washington), 2018-08, Vol.90 (15), p.8865-8872

2018

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Regeneration of peroxiredoxins during recovery after oxidative stress: only some overoxidized peroxiredoxins can be reduced during recovery after oxidative stress

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37146-37153

2003

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Regeneration of Peroxiredoxins during Recovery after Oxidative Stress

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37146-37153

2003

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Analytical characterization of biosimilar antibodies and Fc-fusion proteins

TrAC, Trends in analytical chemistry (Regular ed.), 2013-07, Vol.48, p.81-95

2013

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Middle Level IM–MS and CIU Experiments for Improved Therapeutic Immunoglobulin Subclass Fingerprinting

Analytical chemistry (Washington), 2020-07, Vol.92 (13), p.8827-8835

2020

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Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates

Expert review of proteomics, 2016-02, Vol.13 (2), p.157-183

2016

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High-Resolution IMS–MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody

Journal of the American Society for Mass Spectrometry, 2021-10, Vol.32 (10), p.2505-2512

2021

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Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine‐linked antibody drug conjugate

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies

Characterization of Therapeutic Antibodies and Related Products

Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody

Innovative Native MS Methodologies for Antibody Drug Conjugate Characterization: High Resolution Native MS and IM-MS for Average DAR and DAR Distribution Assessment

Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation

Protocols for the analytical characterization of therapeutic monoclonal antibodies. I – Non-denaturing chromatographic techniques

Development of a fast workflow to screen the charge variants of therapeutic antibodies

Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry techniques

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress

The Brown Algal Kelp Laminaria digitata Features Distinct Bromoperoxidase and Iodoperoxidase Activities

Vanadium-dependent iodoperoxidases in Laminaria digitata, a novel biochemical function diverging from brown algal bromoperoxidases

Adsorption and recovery issues of recombinant monoclonal antibodies in reversed-phase liquid chromatography

Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities

The way forward, enhanced characterization of therapeutic antibody glycosylation: Comparison of three level mass spectrometry-based strategies

Use of PASEF for Accelerated Protein Sequence Confirmation and De Novo Sequencing with High Data Quality

Full validation of therapeutic antibody sequences by middle-up mass measurements and middle-down protein sequencing

Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies

Regeneration of peroxiredoxins during recovery after oxidative stress: only some overoxidized peroxiredoxins can be reduced during recovery after oxidative stress

Regeneration of Peroxiredoxins during Recovery after Oxidative Stress

Analytical characterization of biosimilar antibodies and Fc-fusion proteins

Middle Level IM–MS and CIU Experiments for Improved Therapeutic Immunoglobulin Subclass Fingerprinting

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates

High-Resolution IMS–MS to Assign Additional Disulfide Bridge Pairing in Complementarity-Determining Regions of an IgG4 Monoclonal Antibody

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