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The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer

Scientific reports, 2022-01, Vol.12 (1), p.293-12, Article 293

2022

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Rexinoids Modulate Effector T Cell Expression of Mucosal Homing Markers CCR9 and α4β7 Integrin and Direct Their Migration In Vitro

Frontiers in immunology, 2022-01, Vol.13, p.746484-746484

2022

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An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene

International journal of molecular sciences, 2022-12, Vol.23 (24), p.16213

2022

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A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics

Steroids, 2018-07, Vol.135, p.36-49

2018

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Antiviral activity of metal chelates of caffeic acid and similar compounds towards herpes simplex, VSV-Ebola pseudotyped and vaccinia viruses

Antiviral research, 2018-12, Vol.160, p.143-150

2018

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Development of Bexarotene Analogs for Treating Cutaneous T-Cell Lymphomas

Cells (Basel, Switzerland), 2023-11, Vol.12 (21), p.2575

2023

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Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.2019, p.95

2019

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Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.2019, p.109

2019

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The Polyhomologation of 1-Boraadamantane: Mapping the Migration Pathways of a Propagating Macrotricyclic Trialkylborane

Journal of the American Chemical Society, 2003-10, Vol.125 (40), p.12179-12195

2003

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Aspartate β‐hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma

Hepatology (Baltimore, Md.), 2016-04, Vol.63 (4), p.1213-1226

2016

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Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles

Pharmacology research & perspectives, 2015-03, Vol.3 (2), p.e00122-n/a

2015

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Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention

Cancer prevention research (Philadelphia, Pa.), 2019-04, Vol.12 (4), p.211-224

2019

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Evaluating Novel RXR Agonists That Induce ApoE and Tyrosine Hydroxylase in Cultured Human Glioblastoma Cells

ACS chemical neuroscience, 2021-03, Vol.12 (5), p.857-871

2021

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Molecular dynamics simulations and molecular flooding studies of the retinoid X-receptor ligand binding domain

Journal of molecular modeling, 2017-03, Vol.23 (3), p.98-9, Article 98

2017

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Visually Following the Hydrogenation of Curcumin to Tetrahydrocurcumin in a Natural Product Experiment That Enhances Student Understanding of NMR Spectroscopy

Journal of chemical education, 2013-07, Vol.90 (7), p.930-933

2013

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Modeling, Synthesis and Biological Evaluation of Potential Retinoid X Receptor (RXR) Selective Agonists: Novel Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene)

Journal of medicinal chemistry, 2009-10, Vol.52 (19), p.5950-5966

2009

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Extraction, Purification, and Spectroscopic Characterization of a Mixture of Capsaicinoids

Journal of chemical education, 2011-11, Vol.88 (11), p.1574-1579

2011

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Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists

Bioorganic & medicinal chemistry, 2013-02, Vol.21 (3), p.693-702

2013

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Synthesis of 2,5-Dichloro-2,5-dimethylhexane by an SN1 Reaction

Journal of chemical education, 2010-01, Vol.87 (1), p.81-83

2010

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The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer

Rexinoids Modulate Effector T Cell Expression of Mucosal Homing Markers CCR9 and α4β7 Integrin and Direct Their Migration In Vitro

An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene

Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB)

A novel gene expression analytics-based approach to structure aided design of rexinoids for development as next-generation cancer therapeutics

Antiviral activity of metal chelates of caffeic acid and similar compounds towards herpes simplex, VSV-Ebola pseudotyped and vaccinia viruses

Development of Bexarotene Analogs for Treating Cutaneous T-Cell Lymphomas

Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN

Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN

The Polyhomologation of 1-Boraadamantane: Mapping the Migration Pathways of a Propagating Macrotricyclic Trialkylborane

Aspartate β‐hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinoma

Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles

Rexinoids Induce Differential Gene Expression in Human Glioblastoma Cells and Protein–Protein Interactions in a Yeast Two-Hybrid System

Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention

Evaluating Novel RXR Agonists That Induce ApoE and Tyrosine Hydroxylase in Cultured Human Glioblastoma Cells

Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4‑[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6‑(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN)

Molecular dynamics simulations and molecular flooding studies of the retinoid X-receptor ligand binding domain

Visually Following the Hydrogenation of Curcumin to Tetrahydrocurcumin in a Natural Product Experiment That Enhances Student Understanding of NMR Spectroscopy

Modeling, Synthesis and Biological Evaluation of Potential Retinoid X Receptor (RXR) Selective Agonists: Novel Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene)

Extraction, Purification, and Spectroscopic Characterization of a Mixture of Capsaicinoids

Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists

Modeling, Synthesis and Biological Evaluation of Potential RetinoidX Receptor-Selective Agonists: Novel Halogenated Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene)

Modeling, Synthesis and Biological Evaluation of Potential Retinoid X Receptor-Selective Agonists: Novel Halogenated Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene)

Synthesis of 2,5-Dichloro-2,5-dimethylhexane by an SN1 Reaction

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