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Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration

Alzheimer's research & therapy, 2020-07, Vol.12 (1), p.1-84, Article 84

2020

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A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors

British journal of pharmacology, 2013-03, Vol.168 (5), p.1118-1132

2013

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Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia

Neuropharmacology, 2012-03, Vol.62 (3), p.1359-1370

2012

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The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function

Biochemical Society transactions, 2004-06, Vol.32 (Pt3), p.529

2004

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MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.314-328

2011

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The role of K2P channels in anaesthesia and sleep

Pflügers Archiv, 2015-05, Vol.467 (5), p.907-916

2015

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Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.68

2017

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Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.329-344

2011

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Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination

British journal of pharmacology, 1996-02, Vol.117 (3), p.521-527

1996

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Novel compounds selectively enhance δ subunit containing GABAA receptors and increase tonic currents in thalamus

Neuropharmacology, 2009-01, Vol.56 (1), p.182-189

2009

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Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus

Neuropharmacology, 2009-01, Vol.56 (1), p.182

2009

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Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors

Molecular pharmacology, 1993-12, Vol.44 (6), p.1211-1218

1993

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A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABAA receptors

British journal of pharmacology, 2013-03, Vol.168 (5), p.1118-1132

2013

Volltextzugriff (PDF)

Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

British journal of pharmacology, 2002-08, Vol.136 (7), p.965-974

2002

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Differentiating the role of gamma-aminobutyric acid type A (GABAA) receptor subtypes

Biochemical Society transactions, 2004-06, Vol.32 (Pt3), p.553

2004

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Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat

European journal of pain, 2015-04, Vol.19 (4), p.554-566

2015

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Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes

Molecular pharmacology, 1993-02, Vol.43 (2), p.240-244

1993

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The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (10), p.4569-4573

1994

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Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site

Molecular pharmacology, 1995-02, Vol.47 (2), p.374

1995

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Growth factors regulate the survival and fate of cells derived from human neurospheres

Nature biotechnology, 2001-05, Vol.19 (5), p.475-479

2001

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A novel allosteric modulatory site on the GABAA receptor beta subunit

Neuron (Cambridge, Mass.), 1994-04, Vol.12 (4), p.775-782

1994

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Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations

Molecular pharmacology, 1994-11, Vol.46 (5), p.957-963

1994

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Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors

Molecular pharmacology, 1993-08, Vol.44 (2), p.437-442

1993

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Preferential co-assembly of recombinant NMDA receptors composed of three different subunits

Neuroreport, 1993-09, Vol.4 (12), p.1347-1349

1993

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beta-Carboline gamma-aminobutyric acidA receptor inverse agonists modulate gamma-aminobutyric acid via the loreclezole binding site as well as the benzodiazepine site

Molecular pharmacology, 1995-12, Vol.48 (6), p.965

1995

Volltextzugriff (PDF)

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Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration

A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors

Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia

The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function

MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

The role of K2P channels in anaesthesia and sleep

Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression

Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination

Novel compounds selectively enhance δ subunit containing GABAA receptors and increase tonic currents in thalamus

Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus

Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors

A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABAA receptors

Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

Differentiating the role of gamma-aminobutyric acid type A (GABAA) receptor subtypes

Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat

Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes

The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site

Growth factors regulate the survival and fate of cells derived from human neurospheres

A novel allosteric modulatory site on the GABAA receptor beta subunit

Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations

Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors

Preferential co-assembly of recombinant NMDA receptors composed of three different subunits

beta-Carboline gamma-aminobutyric acidA receptor inverse agonists modulate gamma-aminobutyric acid via the loreclezole binding site as well as the benzodiazepine site

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