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Mast cell proteases: multifaceted regulators of inflammatory disease

Blood, 2010-06, Vol.115 (24), p.4981-4990

2010

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Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma

Scientific reports, 2023-09, Vol.13 (1), p.16261-16261, Article 16261

2023

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Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma

PloS one, 2024-04, Vol.19 (4), p.e0300668-e0300668

2024

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Quantitative Transcriptome Analysis of Purified Equine Mast Cells Identifies a Dominant Mucosal Mast Cell Population with Possible Inflammatory Functions in Airways of Asthmatic Horses

International journal of molecular sciences, 2022-11, Vol.23 (22), p.13976

2022

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Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity

Frontiers in immunology, 2023, Vol.14, p.1136780-1136780

2023

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The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach

Frontiers in immunology, 2018-06, Vol.9, p.1487-1487

2018

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The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus

PloS one, 2015-06, Vol.10 (6), p.e0127032

2015

Volltextzugriff (PDF)

Mouse Mast Cell Protease 4 Is the Major Chymase in Murine Airways and Has a Protective Role in Allergic Airway Inflammation

The Journal of immunology (1950), 2009-11, Vol.183 (10), p.6369-6376

2009

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Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12

PloS one, 2011-09, Vol.6 (9), p.e25222-e25222

2011

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Shrimp‐ and mite sensitization in a Swedish study: Influence on allergic disorders and lung function

Clinical and translational allergy, 2022-10, Vol.12 (10), p.e12198-n/a

2022

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Mast Cell Differentiation and Activation Is Closely Linked to Expression of Genes Coding for the Serglycin Proteoglycan Core Protein and a Distinct Set of Chondroitin Sulfate and Heparin Sulfotransferases

The Journal of immunology (1950), 2009-12, Vol.183 (11), p.7073-7083

2009

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Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase

Molecular immunology, 2010-04, Vol.47 (7), p.1467-1475

2010

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Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice

Journal of leukocyte biology, 2009-03, Vol.85 (3), p.401-408

2009

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Transient Beneficial Effects of Exendin-4 Treatment on the Function of Microencapsulated Mouse Pancreatic Islets

Cell transplantation, 2007-01, Vol.16 (1), p.15-22

2007

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Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation

Mucosal immunology, 2013-09, Vol.6 (5), p.911-920

2013

Volltextzugriff (PDF)

Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice

Inflammation, 2024-07

2024

Volltextzugriff (PDF)

Circulating mast cell progenitors increase in frequency during natural birch pollen exposure in allergic asthma patients

Allergy (Copenhagen), 2023, Vol.78 (11), p.2959

2023

Volltextzugriff (PDF)

Circulating mast cell progenitors increase during natural birch pollen exposure in allergic asthma patients

Allergy (Copenhagen), 2023-11, Vol.78 (11), p.2959-2968

2023

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Carboxypeptidase inhibition by NvCI suppresses airway hyperreactivity in a mouse asthma model

Allergy (Copenhagen), 2021-07, Vol.76 (7), p.2234-2237

2021

Volltextzugriff (PDF)

Targeting the carboxypeptidase activity: a promising strategy for asthma treatment

European Respiratory Journal, 2022, Vol.60, p.2148

2022

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Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism

Cellular microbiology, 2019-09, Vol.21 (9), p.e13064-n/a

2019

Volltextzugriff (PDF)

Mast cells promote melanoma colonization of lungs

Oncotarget, 2016-10, Vol.7 (42), p.68990-69001

2016

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Equine Airway Mast Cells are Sensitive to Cell Death Induced by Lysosomotropic Agents

Scandinavian journal of immunology, 2017-01, Vol.85 (1), p.30-34

2017

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IL‐6 and IL‐17A degradation by mast cells is mediated by a serglycin:serine protease axis

Immunity, Inflammation and Disease, 2016-03, Vol.4 (1), p.70-79

2016

Volltextzugriff (PDF)

Mast cells limit extracellular levels of IL-13 via a serglycin proteoglycan-serine protease axis

Biological chemistry, 2012-12, Vol.393 (12), p.1555-1567

2012

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Mast cell proteases: multifaceted regulators of inflammatory disease

Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma

Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma

Quantitative Transcriptome Analysis of Purified Equine Mast Cells Identifies a Dominant Mucosal Mast Cell Population with Possible Inflammatory Functions in Airways of Asthmatic Horses

Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity

The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach

The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus

Mouse Mast Cell Protease 4 Is the Major Chymase in Murine Airways and Has a Protective Role in Allergic Airway Inflammation

Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12

Shrimp‐ and mite sensitization in a Swedish study: Influence on allergic disorders and lung function

Mast Cell Differentiation and Activation Is Closely Linked to Expression of Genes Coding for the Serglycin Proteoglycan Core Protein and a Distinct Set of Chondroitin Sulfate and Heparin Sulfotransferases

Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase

Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice

Transient Beneficial Effects of Exendin-4 Treatment on the Function of Microencapsulated Mouse Pancreatic Islets

Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation

Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice

Circulating mast cell progenitors increase in frequency during natural birch pollen exposure in allergic asthma patients

Circulating mast cell progenitors increase during natural birch pollen exposure in allergic asthma patients

Carboxypeptidase inhibition by NvCI suppresses airway hyperreactivity in a mouse asthma model

Targeting the carboxypeptidase activity: a promising strategy for asthma treatment

Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism

Mast cells promote melanoma colonization of lungs

Equine Airway Mast Cells are Sensitive to Cell Death Induced by Lysosomotropic Agents

IL‐6 and IL‐17A degradation by mast cells is mediated by a serglycin:serine protease axis

Mast cells limit extracellular levels of IL-13 via a serglycin proteoglycan-serine protease axis

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