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Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3826-3832

2013

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Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma

Molecular cancer therapeutics, 2017-01, Vol.16 (1), p.193-204

2017

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CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling

Molecular cancer therapeutics, 2007-08, Vol.6 (8), p.2249-2260

2007

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Phase-locked signals elucidate circuit architecture of an oscillatory pathway

PLoS computational biology, 2010-12, Vol.6 (12), p.e1001040-e1001040

2010

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Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway

Beilstein journal of organic chemistry, 2013-05, Vol.9 (1), p.966-973

2013

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Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.665-672

2010

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How Prepared Are College Freshmen Athletes for the Rigors of College Strength and Conditioning? A Survey of College Strength and Conditioning Coaches

Journal of strength and conditioning research, 2014-10, Vol.28 (10), p.2746-2753

2014

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Selectivity and Anti-Parkinson’s Potential of Thiadiazolidinone RGS4 Inhibitors

ACS chemical neuroscience, 2015-06, Vol.6 (6), p.911-919

2015

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Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors

Biochemical and biophysical research communications, 2002-05, Vol.293 (4), p.1233-1241

2002

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Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay

Cellular signalling, 2013-12, Vol.25 (12), p.2848-2855

2013

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Hi-Fi transmission of periodic signals amid cell-to-cell variability

Molecular bioSystems, 2011-07, Vol.7 (7), p.2238-2244

2011

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Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics

Integrative biology (Cambridge), 2013-01, Vol.5 (7), p.932-939

2013

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Conditional disruption of interactions between Gαi2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury

BMC pharmacology & toxicology, 2014-06, Vol.15 (1), p.29-29, Article 29

2014

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Gαi2 signaling: friend or foe in cardiac injury and heart failure?

Naunyn-Schmiedeberg's archives of pharmacology, 2012-05, Vol.385 (5), p.443-453

2012

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Capillary Electrophoresis Assay for G Protein-Coupled Receptor-Mediated GTPase Activity

Analytical chemistry (Washington), 2007-02, Vol.79 (3), p.1158-1163

2007

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A Spatial Focusing Model for G Protein Signals

The Journal of biological chemistry, 2003-02, Vol.278 (9), p.7278-7284

2003

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Cotransfection of second and third intracellular loop fragments inhibit angiotensin AT1a receptor activation of phospholipase C in HEK-293 cells

The Journal of pharmacology and experimental therapeutics, 1998-04, Vol.285 (1), p.216

1998

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Small molecule targeting of RhoC‐regulated gene transcription in metastatic, undifferentiated melanoma

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamicsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ib40032h

2013-06

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Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks

Microarrays (Basel, Switzerland), 2016-05, Vol.5 (2), p.13

2016

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Conditional disruption of interactions between G[alpha]i2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury

BMC pharmacology & toxicology, 2014-06, Vol.15

2014

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Phase-Locked Signals Elucidate Circuit Architecture of an Oscillatory Pathway: e1001040

PLoS computational biology, 2010-12, Vol.6 (12)

2010

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A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding

The Journal of biological chemistry, 2003-02, Vol.278 (9), p.7278

2003

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Modulation of K+ and Ca2+ currents in cultured neurons by an angiotensin II type 1a receptor peptide

American Journal of Physiology: Cell Physiology, 1997-09, Vol.273 (3), p.C1040-C1048

1997

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Inverse Agonist Activity at the Î±2A-Adrenergic Receptor

Molecular pharmacology, 2001-03, Vol.59 (3), p.532

2001

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Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents

Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma

CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling

Phase-locked signals elucidate circuit architecture of an oscillatory pathway

Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway

Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423

How Prepared Are College Freshmen Athletes for the Rigors of College Strength and Conditioning? A Survey of College Strength and Conditioning Coaches

Selectivity and Anti-Parkinson’s Potential of Thiadiazolidinone RGS4 Inhibitors

Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors

Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay

Hi-Fi transmission of periodic signals amid cell-to-cell variability

Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics

Conditional disruption of interactions between Gαi2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury

Gαi2 signaling: friend or foe in cardiac injury and heart failure?

Capillary Electrophoresis Assay for G Protein-Coupled Receptor-Mediated GTPase Activity

A Spatial Focusing Model for G Protein Signals

Cotransfection of second and third intracellular loop fragments inhibit angiotensin AT1a receptor activation of phospholipase C in HEK-293 cells

Small molecule targeting of RhoC‐regulated gene transcription in metastatic, undifferentiated melanoma

Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamicsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ib40032h

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks

Conditional disruption of interactions between G[alpha]i2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury

Phase-Locked Signals Elucidate Circuit Architecture of an Oscillatory Pathway: e1001040

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding

Modulation of K+ and Ca2+ currents in cultured neurons by an angiotensin II type 1a receptor peptide

Inverse Agonist Activity at the Î±2A-Adrenergic Receptor

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