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Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells

Haematologica (Roma), 2018-09, Vol.103 (9), p.1472-1483

2018

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Genetics of Congenital Adrenal Hyperplasia

Endocrinology and metabolism clinics of North America, 2017-06, Vol.46 (2), p.435-458

2017

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Structural and Thermodynamic Characterization of Protein–Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.5115-5120

2016

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A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain

Scientific reports, 2015-04, Vol.5 (1), p.9542-9542, Article 9542

2015

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Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein

Frontiers in chemistry, 2021-07, Vol.9, p.659764-659764

2021

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Junction Site Analysis of Chimeric CYP21A1P/CYP21A2 Genes in 21-Hydroxylase Deficiency

Clinical chemistry (Baltimore, Md.), 2012-02, Vol.58 (2), p.421-430

2012

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Structure-Based Discovery of PDEs Inhibitors

Current topics in medicinal chemistry, 2016-01, Vol.16 (9), p.917-933

2016

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P145: Microcephaly in atypical Silver-Russell syndrome caused by defects in PLAG1

Genetics in Medicine Open, 2023, Vol.1 (1), p.100174, Article 100174

2023

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A TNXB splice donor site variant as a cause of hypermobility type Ehlers–Danlos syndrome in patients with congenital adrenal hyperplasia

Molecular genetics & genomic medicine, 2021-02, Vol.9 (2), p.e1556-n/a

2021

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Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families

European journal of endocrinology, 2011-06, Vol.164 (6), p.977-984

2011

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Virtual screening and structure-based discovery of indole acylguanidines as potent β-secretase (BACE1) inhibitors

Molecules (Basel, Switzerland), 2013-05, Vol.18 (5), p.5706-5722

2013

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Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations

Acta crystallographica. Section D, Biological crystallography., 2012-01, Vol.68 (1), p.13-25

2012

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A Novel Intronic Pathogenic Variant in STAR With a Dominant Negative Mechanism Causes Attenuated Lipoid Congenital Adrenal Hyperplasia

JIM - high impact case reports, 2021, Vol.9, p.23247096211014685-23247096211014685

2021

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Comprehensive Mutation Analysis of the CYP21A2 Gene

The Journal of molecular diagnostics : JMD, 2013-11, Vol.15 (6), p.745-753

2013

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The phenotypic spectrum of contiguous deletion of CYP21A2 and tenascin XB: Quadricuspid aortic valve and other midline defects

American journal of medical genetics. Part A, 2009-12, Vol.149A (12), p.2803-2808

2009

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Significant Association Between the Genetic Variations in the 5′ End of the N-Methyl-D-Aspartate Receptor Subunit Gene GRIN1 and Schizophrenia

Biological psychiatry (1969), 2006-04, Vol.59 (8), p.747-753

2006

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SS31 attenuates oxidative stress and neuronal apoptosis in early brain injury following subarachnoid hemorrhage possibly by the mitochondrial pathway

Neuroscience letters, 2020-01, Vol.717, p.134654-134654, Article 134654

2020

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Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent

Journal of medicinal chemistry, 2019-06, Vol.62 (11), p.5579-5593

2019

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Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors

Bioorganic & medicinal chemistry, 2015-05, Vol.23 (9), p.1963-1974

2015

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Fragment-Based Drug Discovery of 2‑Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.3833-3851

2013

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Natural product piperine alleviates experimental allergic encephalomyelitis in mice by targeting dihydroorotate dehydrogenase

Biochemical pharmacology, 2020-07, Vol.177, p.114000, Article 114000

2020

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Comprehensive Genetic Analysis of 182 Unrelated Families with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

The journal of clinical endocrinology and metabolism, 2011-01, Vol.96 (1), p.E161-E172

2011

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Genetics of congenital adrenal hyperplasia

Baillière's best practice & research. Clinical endocrinology & metabolism, 2009-04, Vol.23 (2), p.181-192

2009

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No association between the promoter variants of tumor necrosis factor alpha (TNF-α) and schizophrenia in Chinese Han population

Neuroscience letters, 2004-08, Vol.366 (2), p.139-143

2004

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Comprehensive mutation analysis of the CYP21A2 gene: an efficient multistep approach to the molecular diagnosis of congenital adrenal hyperplasia

The Journal of molecular diagnostics : JMD, 2013-11, Vol.15 (6), p.745-753

2013

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Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells

Genetics of Congenital Adrenal Hyperplasia

Structural and Thermodynamic Characterization of Protein–Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors

A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain

Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein

Junction Site Analysis of Chimeric CYP21A1P/CYP21A2 Genes in 21-Hydroxylase Deficiency

Structure-Based Discovery of PDEs Inhibitors

P145: Microcephaly in atypical Silver-Russell syndrome caused by defects in PLAG1

A TNXB splice donor site variant as a cause of hypermobility type Ehlers–Danlos syndrome in patients with congenital adrenal hyperplasia

Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families

Virtual screening and structure-based discovery of indole acylguanidines as potent β-secretase (BACE1) inhibitors

Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations

A Novel Intronic Pathogenic Variant in STAR With a Dominant Negative Mechanism Causes Attenuated Lipoid Congenital Adrenal Hyperplasia

Comprehensive Mutation Analysis of the CYP21A2 Gene

The phenotypic spectrum of contiguous deletion of CYP21A2 and tenascin XB: Quadricuspid aortic valve and other midline defects

Significant Association Between the Genetic Variations in the 5′ End of the N-Methyl-D-Aspartate Receptor Subunit Gene GRIN1 and Schizophrenia

SS31 attenuates oxidative stress and neuronal apoptosis in early brain injury following subarachnoid hemorrhage possibly by the mitochondrial pathway

Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent

Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors

Fragment-Based Drug Discovery of 2‑Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain

Natural product piperine alleviates experimental allergic encephalomyelitis in mice by targeting dihydroorotate dehydrogenase

Comprehensive Genetic Analysis of 182 Unrelated Families with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

Genetics of congenital adrenal hyperplasia

No association between the promoter variants of tumor necrosis factor alpha (TNF-α) and schizophrenia in Chinese Han population

Comprehensive mutation analysis of the CYP21A2 gene: an efficient multistep approach to the molecular diagnosis of congenital adrenal hyperplasia

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