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Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models

British journal of pharmacology, 2016-01, Vol.173 (1), p.155-166

2016

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P.2.d.012 Further characterization of norquetiapine and quetiapine in rodent models of antidepressant and anxiolytic action

European neuropsychopharmacology, 2008, Vol.18, p.S351-S352

2008

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P.2.h.006 Quetiapine's antidepressant properties: direct and indirect pharmacologic actions on norepinephrine and serotonin receptors

European neuropsychopharmacology, 2007, Vol.17, p.S401-S401

2007

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P.2.h.004 Anxiolytic effects of quetiapine in rat punished responding: mechanism of action and the role of D2 antagonism

European neuropsychopharmacology, 2007, Vol.17, p.S399-S400

2007

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Low affinity use-dependent NMDA receptor antagonists show promise for clinical development

Amino acids, 2000-01, Vol.19 (1), p.151-155

2000

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Homogeneity of regional brain lead concentrations

Neurotoxicology (Park Forest South), 1994, Vol.15 (2), p.295

1994

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Long-Term Functional End Points Following Middle Cerebral Artery Occlusion in the Rat

Pharmacology, biochemistry and behavior, 2000-03, Vol.65 (3), p.553-562

2000

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Apparent mediation of the stimulus properties of a low dose of quinpirole by dopaminergic autoreceptors

The Journal of pharmacology and experimental therapeutics, 1993-08, Vol.266 (2), p.526

1993

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Postnatal lead exposure induces supersensitivity to the stimulus properties of a D2-D3 agonist

Brain research, 1992-12, Vol.598 (1-2), p.162-172

1992

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Time course of postnatal lead-induced changes in dopamine receptors and their relationship to changes in dopamine sensitivity

Neurotoxicology (Park Forest South), 1994, Vol.15 (4), p.853

1994

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Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists

Brain research, 1991-07, Vol.553 (1), p.65-74

1991

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Functional alterations in dopamine systems assessed using drug discrimination procedures

Neurotoxicology (Park Forest South), 1993, Vol.14 (2-3), p.105

1993

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Behavioral manifestations of prolonged lead exposure initiated at different stages of the life cycle: II. Delayed spatial alternation

Neurotoxicology (Park Forest South), 1991, Vol.12 (4), p.761

1991

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Behavioral differentiation of the stimulus properties of a dopaminergic D1 agonist from a D2 agonist

The Journal of pharmacology and experimental therapeutics, 1989-09, Vol.250 (3), p.800

1989

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Comparison of antidepressant and anxiolytic activity of quetiapine and its metabolite, norquetiapine, in rodent models

The international journal of neuropsychopharmacology, 2008-07, Vol.11, p.119

2008

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Selective muscarinic M 1 antagonists: drug design and discovery

Drug discovery today, 1997-08, Vol.2 (8), p.341-350

1997

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Selective muscarinic M1 antagonists : drug design and discovery

Drug discovery today, 1997-08, Vol.2 (8), p.341-350

1997

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Selective muscarinic M sub(1) antagonists: Drug design and discovery

Drug discovery today, 1997-08, Vol.2 (8), p.341-350

1997

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Lead retards development of Drosophila melanogaster

Comparative biochemistry and physiology. C, Comparative pharmacology, 1992-05, Vol.102 (1), p.45-49

1992

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Effects of nicotinic agonists and antagonists on spatial working memory in normal adult and aged rats: Nicotinic therapeutics. I

Drug development research, 1994, Vol.31 (1), p.24-31

1994

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Low level lead exposure increases sensitivity to the stimulus properties of dopamine D sub(1) and D sub(2) agonists

Brain research, 1991-01, Vol.553 (1), p.65-74

1991

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Postnatal lead exposure induces supersensitivity to the stimulus properties of a D sub(2)-D sub(3) agonist

Brain research, 1992-01, Vol.598 (1-2), p.162-172

1992

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Effects of nicotinic agonists and antagonists on spatial working memory in normal adult and aged rats

Drug development research, 1994-01, Vol.31 (1), p.24-31

1994

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Development of a pharmacological target profile for muscarinic agonists: Challenges and opportunities for developing muscarinic receptor subtype-based therapeutic agents

Drug development research, 1997, Vol.40 (2), p.117-132

1997

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Development of a pharmacological target profile for muscarinic agonists

Drug development research, 1997-02, Vol.40 (2), p.117-132

1997

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Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models

P.2.d.012 Further characterization of norquetiapine and quetiapine in rodent models of antidepressant and anxiolytic action

P.2.h.006 Quetiapine's antidepressant properties: direct and indirect pharmacologic actions on norepinephrine and serotonin receptors

P.2.h.004 Anxiolytic effects of quetiapine in rat punished responding: mechanism of action and the role of D2 antagonism

Low affinity use-dependent NMDA receptor antagonists show promise for clinical development

Homogeneity of regional brain lead concentrations

Long-Term Functional End Points Following Middle Cerebral Artery Occlusion in the Rat

Apparent mediation of the stimulus properties of a low dose of quinpirole by dopaminergic autoreceptors

Postnatal lead exposure induces supersensitivity to the stimulus properties of a D2-D3 agonist

Time course of postnatal lead-induced changes in dopamine receptors and their relationship to changes in dopamine sensitivity

Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists

Functional alterations in dopamine systems assessed using drug discrimination procedures

Behavioral manifestations of prolonged lead exposure initiated at different stages of the life cycle: II. Delayed spatial alternation

Behavioral differentiation of the stimulus properties of a dopaminergic D1 agonist from a D2 agonist

Comparison of antidepressant and anxiolytic activity of quetiapine and its metabolite, norquetiapine, in rodent models

Selective muscarinic M 1 antagonists: drug design and discovery

Selective muscarinic M1 antagonists : drug design and discovery

Selective muscarinic M sub(1) antagonists: Drug design and discovery

Lead retards development of Drosophila melanogaster

Effects of nicotinic agonists and antagonists on spatial working memory in normal adult and aged rats: Nicotinic therapeutics. I

Low level lead exposure increases sensitivity to the stimulus properties of dopamine D sub(1) and D sub(2) agonists

Postnatal lead exposure induces supersensitivity to the stimulus properties of a D sub(2)-D sub(3) agonist

Effects of nicotinic agonists and antagonists on spatial working memory in normal adult and aged rats

Development of a pharmacological target profile for muscarinic agonists: Challenges and opportunities for developing muscarinic receptor subtype-based therapeutic agents

Development of a pharmacological target profile for muscarinic agonists

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