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Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions

Diabetologia, 2007-06, Vol.50 (6), p.1277-1287

2007

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Hypothalamic orexin expression: modulation by blood glucose and feeding

Diabetes (New York, N.Y.), 1999-11, Vol.48 (11), p.2132-2137

1999

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Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution

British journal of pharmacology, 1999-12, Vol.128 (7), p.1570-1576

1999

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Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding

Diabetes (New York, N.Y.), 1999-02, Vol.48 (2), p.267-271

1999

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Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity

Diabetes (New York, N.Y.), 1997-11, Vol.46 (11), p.1782-1785

1997

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Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity

Diabetes (New York, N.Y.), 1997-11, Vol.46 (11), p.1782-1785

1997

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Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC‐555

British journal of pharmacology, 1998-12, Vol.125 (8), p.1708-1714

1998

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Regulation of Neuropeptide Y Release by Neuropeptide Y Receptor Ligands and Calcium Channel Antagonists in Hypothalamic Slices

Journal of neurochemistry, 1999-08, Vol.73 (2), p.641-646

1999

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The development of overt diabetes in young Zucker Diabetic Fatty (ZDF) rats and the effects of chronic MCC‐555 treatment

British journal of pharmacology, 1998-10, Vol.125 (4), p.767-770

1998

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Regionally-selective down-regulation of NPY receptor subtypes in the obese Zucker rat. Relationship to the Y5 ‘feeding’ receptor

Brain research, 1997-05, Vol.758 (1), p.17-25

Widdowson, P.S.

1997

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Early Leptin Response to a Palatable Diet Predicts Dietary Obesity in Rats: Key Role of Melanocortin‐4 Receptors in the Ventromedial Hypothalamic Nucleus

Journal of neurochemistry, 2000-03, Vol.74 (3), p.1224-1228

2000

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Quantitative receptor autoradiography demonstrates a differential distribution of neuropeptide-Y Y1 and Y2 receptor subtypes in human and rat brain

Brain research, 1993-12, Vol.631 (1), p.27-38

WIDDOWSON, P. S

1993

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Reciprocal regional changes in brain NPY receptor density during dietary restriction and dietary-induced obesity in the rat

Brain research, 1997-11, Vol.774 (1), p.1-10

1997

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Reduced Neuropeptide Y Concentrations in Suicide Brain

Journal of neurochemistry, 1992-07, Vol.59 (1), p.73-80

1992

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Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: a role for endogenous cannabinoids in driving appetite for palatable food?

Brain research, 2002-10, Vol.952 (2), p.232-238

2002

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Neuropathological Studies on Cycloate-Induced Neuronal Cell Death in the Rat Brain

Neurotoxicology (Park Forest South), 2005, Vol.26 (1), p.125-132

2005

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Influence of age on the passage of paraquat through the blood-brain barrier in rats: A distribution and pathological examination

Human & experimental toxicology, 1996-03, Vol.15 (3), p.231-236

1996

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No changes in behaviour, nigro-striatal system neurochemistry or neuronal cell death following toxic multiple oral paraquat administration to rats

Human & experimental toxicology, 1996-07, Vol.15 (7), p.583-591

1996

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Ethanol‐Induced Increase in Endogenous Dopamine Release May Involve Endogenous Opiates

Journal of neurochemistry, 1992-07, Vol.59 (1), p.157-163

1992

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NMDA Receptors in Rat Cerebellum and Forebrain: Subtle Differences in Pharmacology and Modulation

Journal of neurochemistry, 1995-02, Vol.64 (2), p.651-661

1995

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The Reproductive Toxicity of Molinate and Metabolites to the Male Rat: Effects on Testosterone and Sperm Morphology

Toxicology and applied pharmacology, 1998-07, Vol.151 (1), p.22-32

1998

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L-2-Chloropropionic Acid-Induced Neurotoxicity Is Prevented by MK-801: Possible Role of NMDA Receptors in the Neuropathology

Toxicology and applied pharmacology, 1996-01, Vol.136 (1), p.138-145

1996

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Existence of Three Subtypes of Bradykinin B2 Receptors in Guinea Pig

Journal of neurochemistry, 1992-12, Vol.59 (6), p.2125-2133

1992

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Characterization of [125I]‐endothelin‐1 and [125I]‐BQ3020 binding to rat cerebellar endothelin receptors

British journal of pharmacology, 1996-08, Vol.118 (8), p.2126-2130

1996

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Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis

Toxicology and applied pharmacology, 1997-02, Vol.142 (2), p.248-255

1997

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Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions

Hypothalamic orexin expression: modulation by blood glucose and feeding

Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution

Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding

Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity

Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity

Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC‐555

Regulation of Neuropeptide Y Release by Neuropeptide Y Receptor Ligands and Calcium Channel Antagonists in Hypothalamic Slices

The development of overt diabetes in young Zucker Diabetic Fatty (ZDF) rats and the effects of chronic MCC‐555 treatment

Regionally-selective down-regulation of NPY receptor subtypes in the obese Zucker rat. Relationship to the Y5 ‘feeding’ receptor

Early Leptin Response to a Palatable Diet Predicts Dietary Obesity in Rats: Key Role of Melanocortin‐4 Receptors in the Ventromedial Hypothalamic Nucleus

Quantitative receptor autoradiography demonstrates a differential distribution of neuropeptide-Y Y1 and Y2 receptor subtypes in human and rat brain

Reciprocal regional changes in brain NPY receptor density during dietary restriction and dietary-induced obesity in the rat

Reduced Neuropeptide Y Concentrations in Suicide Brain

Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: a role for endogenous cannabinoids in driving appetite for palatable food?

Neuropathological Studies on Cycloate-Induced Neuronal Cell Death in the Rat Brain

Influence of age on the passage of paraquat through the blood-brain barrier in rats: A distribution and pathological examination

No changes in behaviour, nigro-striatal system neurochemistry or neuronal cell death following toxic multiple oral paraquat administration to rats

Ethanol‐Induced Increase in Endogenous Dopamine Release May Involve Endogenous Opiates

NMDA Receptors in Rat Cerebellum and Forebrain: Subtle Differences in Pharmacology and Modulation

The Reproductive Toxicity of Molinate and Metabolites to the Male Rat: Effects on Testosterone and Sperm Morphology

L-2-Chloropropionic Acid-Induced Neurotoxicity Is Prevented by MK-801: Possible Role of NMDA Receptors in the Neuropathology

Existence of Three Subtypes of Bradykinin B2 Receptors in Guinea Pig

Characterization of [125I]‐endothelin‐1 and [125I]‐BQ3020 binding to rat cerebellar endothelin receptors

Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis

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