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C. elegans Males Integrate Food Signals and Biological Sex to Modulate State-Dependent Chemosensation and Behavioral Prioritization

Current biology, 2020-07, Vol.30 (14), p.2695-2706.e4

2020

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Milvexian, an orally bioavailable, small‐molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits

Journal of thrombosis and haemostasis, 2022-02, Vol.20 (2), p.399-408

2022

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The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

BMC biology, 2019-12, Vol.17 (1), p.100-100, Article 100

2019

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Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies

Journal of thrombosis and haemostasis, 2008-05, Vol.6 (5), p.820-829

2008

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Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Journal of medicinal chemistry, 2007-11, Vol.50 (22), p.5339-5356

2007

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Factor Xa Inhibitors: Next-Generation Antithrombotic Agents

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6243-6274

2010

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Pan-metazoan phylogeny of the DMRT gene family: a framework for functional studies

Development genes and evolution, 2014-06, Vol.224 (3), p.175-181

2014

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Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9703-9723

2017

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Discovery of 1-(3‘-Aminobenzisoxazol-5‘-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2‘-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide Hydrochloride (Razaxaban), a Highly Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1729-1744

2005

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In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa

Journal of thrombosis and thrombolysis, 2015-11, Vol.40 (4), p.416-423

2015

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The Prevalence of Huntington's Disease

Neuroepidemiology, 2016-01, Vol.46 (2), p.144-153

2016

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Involvement of endothelial PECAM-1/CD31 in angiogenesis

The American journal of pathology, 1997-09, Vol.151 (3), p.671-677

1997

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Huntington's and the History of Sleep

Journal of Huntington's disease, 2023-01, Vol.12 (2), p.167

Wexler, Alice R

2023

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Transformation of Anionically Activated Trifluoromethyl Groups to Heterocycles under Mild Aqueous Conditions

Organic letters, 2011-04, Vol.13 (7), p.1804-1807

2011

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Nonpeptide Angiotensin II Receptor Antagonists: The Next Generation in Antihypertensive Therapy

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.625-656

1996

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Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (8), p.2432-2435

2013

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Advances in genome sequencing reveal changes in gene content that contribute to arthropod macroevolution

Development genes and evolution, 2023-12, Vol.233 (2), p.59-76

2023

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Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N‑[(1R)‑1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)

Journal of medicinal chemistry, 2015-11, Vol.58 (22), p.9010-9026

2015

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Dynamic, Non-binary Specification of Sexual State in the C. elegans Nervous System

Current biology, 2020-09, Vol.30 (18), p.3617-3623.e3

2020

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Preclinical pharmacokinetics and pharmacodynamics of apixaban, a potent and selective factor Xa inhibitor

European journal of drug metabolism and pharmacokinetics, 2011-09, Vol.36 (3), p.129-139

2011

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Outcomes of Preoperative Versus Postoperative Radiation for Heterotopic Ossification Prevention in Pediatric Patients With Cerebral Palsy Undergoing Proximal Femoral Resection

International journal of radiation oncology, biology, physics, 2014-09, Vol.90 (1), p.S730-S731

2014

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Factor XIa Inhibitors as New Anticoagulants

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7425-7447

2018

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C. elegans Males Integrate Food Signals and Biological Sex to Modulate State-Dependent Chemosensation and Behavioral Prioritization

Milvexian, an orally bioavailable, small‐molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits

The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies

Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Factor Xa Inhibitors: Next-Generation Antithrombotic Agents

Pan-metazoan phylogeny of the DMRT gene family: a framework for functional studies

Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)

Discovery of 1-(3‘-Aminobenzisoxazol-5‘-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2‘-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide Hydrochloride (Razaxaban), a Highly Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor

In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa

The Prevalence of Huntington's Disease

Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1‑(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y1 Antagonist

Involvement of endothelial PECAM-1/CD31 in angiogenesis

Huntington's and the History of Sleep

Transformation of Anionically Activated Trifluoromethyl Groups to Heterocycles under Mild Aqueous Conditions

Nonpeptide Angiotensin II Receptor Antagonists: The Next Generation in Antihypertensive Therapy

Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a Highly Potent, Selective, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor

Advances in genome sequencing reveal changes in gene content that contribute to arthropod macroevolution

Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N‑[(1R)‑1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311)

Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy

Dynamic, Non-binary Specification of Sexual State in the C. elegans Nervous System

Preclinical pharmacokinetics and pharmacodynamics of apixaban, a potent and selective factor Xa inhibitor

Outcomes of Preoperative Versus Postoperative Radiation for Heterotopic Ossification Prevention in Pediatric Patients With Cerebral Palsy Undergoing Proximal Femoral Resection

Factor XIa Inhibitors as New Anticoagulants

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