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LNA (Locked Nucleic Acid): High-Affinity Targeting of Complementary RNA and DNA

Biochemistry (Easton), 2004-10, Vol.43 (42), p.13233-13241

2004

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Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides

Beilstein journal of organic chemistry, 2021-07, Vol.17 (1), p.1828-1848

2021

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Scaffolding along Nucleic Acid Duplexes Using 2′-Amino-Locked Nucleic Acids

Accounts of chemical research, 2014-06, Vol.47 (6), p.1768-1777

2014

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By-product formation in repetitive PCR amplification of DNA libraries during SELEX

PloS one, 2014-12, Vol.9 (12), p.e114693-e114693

2014

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Synthetic Genetic Polymers Capable of Heredity and Evolution

Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6079), p.341-344

2012

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Chirality transmission in macromolecular domains

Nature communications, 2022-01, Vol.13 (1), p.76-76, Article 76

2022

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Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

Chemistry & biodiversity, 2010-03, Vol.7 (3), p.536-542

2010

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Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

Accounts of chemical research, 1999-04, Vol.32 (4), p.301-310

Wengel, Jesper

1999

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Nucleic acid nanotechnology-towards Angstrom-scale engineering

Organic & biomolecular chemistry, 2004-02, Vol.2 (3), p.277-280

Wengel, Jesper

2004

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A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

Nucleic acids research, 2010-09, Vol.38 (17), p.5761

2010

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The Effect of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice

Molecular therapy, 2009-07, Vol.17 (7), p.1225-1233

2009

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microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation

Scientific reports, 2019-04, Vol.9 (1), p.5836-5836, Article 5836

2019

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Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids

Applied microbiology and biotechnology, 2015-05, Vol.99 (9), p.3961-3969

2015

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Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

Nucleic acids research, 2011-02, Vol.39 (3), p.1155

2011

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3'-Pyrene-modified unlocked nucleic acids: synthesis, fluorescence properties and a surprising stabilization effect on duplexes and triplexes

Organic & biomolecular chemistry, 2017-03, Vol.15 (9), p.2073-2085

2017

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Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions

Chemical communications (Cambridge, England), 2018, Vol.54 (57), p.8003-8006

2018

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Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds

Molecular therapy. Nucleic acids, 2020-12, Vol.22, p.994-1003

2020

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Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative

Molecular therapy. Nucleic acids, 2018-03, Vol.10, p.304-316

2018

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Oligonucleotides Containing Aminated 2′-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA

Bioconjugate chemistry, 2017-04, Vol.28 (4), p.1214-1220

2017

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In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3' and 5' thiophosphate linkages

Nucleic acids research, 2020-01, Vol.48 (1), p.63

2020

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Synthesis and Excellent Duplex Stability of Oligonucleotides Containing 2'-Amino-LNA Functionalized with Galactose Units

Molecules (Basel, Switzerland), 2017-05, Vol.22 (5), p.852

2017

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Locked nucleic acid as a novel class of therapeutic agents

RNA biology, 2009-07, Vol.6 (3), p.321-323

2009

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Modulation of i-motif thermodynamic stability by the introduction of UNA (unlocked nucleic acid) monomers

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (2), p.752-755

2011

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Brightness through Local Constraint-LNA-Enhanced FIT Hybridization Probes for In Vivo Ribonucleotide Particle Tracking

Angewandte Chemie (International ed.), 2014-10, Vol.53 (42), p.11370-11375

International ed. in English, 2014

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Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro

International journal of molecular sciences, 2020-03, Vol.21 (7), p.2434

2020

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LNA (Locked Nucleic Acid): High-Affinity Targeting of Complementary RNA and DNA

Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides

Scaffolding along Nucleic Acid Duplexes Using 2′-Amino-Locked Nucleic Acids

By-product formation in repetitive PCR amplification of DNA libraries during SELEX

Synthetic Genetic Polymers Capable of Heredity and Evolution

Chirality transmission in macromolecular domains

Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

Nucleic acid nanotechnology-towards Angstrom-scale engineering

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

The Effect of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice

microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation

Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

3'-Pyrene-modified unlocked nucleic acids: synthesis, fluorescence properties and a surprising stabilization effect on duplexes and triplexes

Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions

Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative

Oligonucleotides Containing Aminated 2′-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA

In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3' and 5' thiophosphate linkages

Synthesis and Excellent Duplex Stability of Oligonucleotides Containing 2'-Amino-LNA Functionalized with Galactose Units

Locked nucleic acid as a novel class of therapeutic agents

Modulation of i-motif thermodynamic stability by the introduction of UNA (unlocked nucleic acid) monomers

Brightness through Local Constraint-LNA-Enhanced FIT Hybridization Probes for In Vivo Ribonucleotide Particle Tracking

Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro

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