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High-Level Carbapenem Resistance in a Klebsiella pneumoniae Clinical Isolate Is Due to the Combination of blaACT-1 β-Lactamase Production, Porin OmpK35/36 Insertional Inactivation, and Down-Regulation of the Phosphate Transport Porin PhoE

Antimicrobial Agents and Chemotherapy, 2006-10, Vol.50 (10), p.3396-3406

2006

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Hydrolysis and Inhibition Profiles of β-Lactamases from Molecular Classes A to D with Doripenem, Imipenem, and Meropenem

Antimicrobial Agents and Chemotherapy, 2010-01, Vol.54 (1), p.565-569

2010

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Affinity of Doripenem and Comparators to Penicillin-Binding Proteins in Escherichia coli and Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 2008-04, Vol.52 (4), p.1510-1512

2008

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Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007-09

Journal of antimicrobial chemotherapy, 2011-10, Vol.66 (10), p.2298-2307

2011

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Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2621-2624

2007

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Interactions of Ceftobiprole with β-Lactamases from Molecular Classes A to D

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3089-3095

2007

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Antistaphylococcal Activities of the New Fluoroquinolone JNJ-Q2

Antimicrobial Agents and Chemotherapy, 2011-12, Vol.55 (12), p.5512-5521

2011

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Synergistic Activity of Ceftobiprole and Vancomycin in a Rat Model of Infective Endocarditis Caused by Methicillin-Resistant and Glycopeptide-Intermediate Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1476-1484

2012

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SME-3, a Novel Member of the Serratia marcescens SME Family of Carbapenem-Hydrolyzing β-Lactamases

Antimicrobial Agents and Chemotherapy, 2006-10, Vol.50 (10), p.3485-3487

2006

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In Vitro Activity of Ceftobiprole against Pathogens from Two Phase 3 Clinical Trials of Complicated Skin and Skin Structure Infections

Antimicrobial Agents and Chemotherapy, 2008-09, Vol.52 (9), p.3418-3423

2008

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Activities of Ceftobiprole and Other β-Lactams against Streptococcus pneumoniae Clinical Isolates from the United States with Defined Substitutions in Penicillin-Binding Proteins PBP 1a, PBP 2b, and PBP 2x

Antimicrobial Agents and Chemotherapy, 2006-07, Vol.50 (7), p.2530-2532

2006

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Genetic and Molecular Characterization of β-Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae with Unusually High Resistance to Ampicillin

Antimicrobial Agents and Chemotherapy, 2004-05, Vol.48 (5), p.1630-1639

2004

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Effects of Ceftobiprole and Oxacillin on mecA Expression in Methicillin-Resistant Staphylococcus aureus Clinical Isolates

Antimicrobial Agents and Chemotherapy, 2010-02, Vol.54 (2), p.956-959

2010

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Enterococcal virulence determinants may be involved in resistance to clinical therapy

Diagnostic microbiology and infectious disease, 2007-05, Vol.58 (1), p.59-65

2007

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Molecular characterisation of meticillin-resistant Staphylococcus aureus isolates from two ceftobiprole Phase 3 complicated skin and skin-structure infection clinical trials

International journal of antimicrobial agents, 2009-08, Vol.34 (2), p.166-168

2009

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High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of bla(ACT-1) beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe

Antimicrobial agents and chemotherapy, 2006-10, Vol.50 (10), p.3396

2006

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Evaluation of the in vitro activities of ceftobiprole and comparators in staphylococcal colony or microtitre plate biofilm assays

International journal of antimicrobial agents, 2014-01, Vol.43 (1), p.32-39

2014

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The Spread of Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae to Upstate New York

Clinical infectious diseases, 2006-08, Vol.43 (3), p.e26-e28

2006

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Hydrolysis and Inhibition Profiles of ?-Lactamases from Molecular Classes A to D with Doripenem, Imipenem, and Meropenem

Antimicrobial agents and chemotherapy, 2010-01, Vol.54 (1), p.565-569

2010

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Activity of doripenem and comparator β-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbp1a, pbp2b and pbp2x

Journal of antimicrobial chemotherapy, 2008-03, Vol.61 (3), p.751-753

2008

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Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

Biochemical pharmacology, 2012-02, Vol.83 (4), p.462-471

2012

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The mouse intranasal challenge model for potency testing of whole-cell pertussis vaccines

Expert review of vaccines, 2014-10, Vol.13 (10), p.1265-1270

2014

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Activities of Ceftobiprole and Other {szligbeta}-Lactams against Streptococcus pneumoniae Clinical Isolates from the United States with Defined Substitutions in Penicillin-Binding Proteins PBP 1a, PBP 2b, and PBP 2x

Antimicrobial agents and chemotherapy, 2006-07, Vol.50 (7), p.2530-2532

2006

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Activity of doripenem and comparator b-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbp1a, pbp2b and pbp2x

Journal of antimicrobial chemotherapy, 2008-03, Vol.61 (3), p.751-753

2008

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Activity of doripenem and comparator p-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbpla, pbp2b and pbp2x

Journal of antimicrobial chemotherapy, 2008, Vol.61 (3), p.751-753

2008

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High-Level Carbapenem Resistance in a Klebsiella pneumoniae Clinical Isolate Is Due to the Combination of blaACT-1 β-Lactamase Production, Porin OmpK35/36 Insertional Inactivation, and Down-Regulation of the Phosphate Transport Porin PhoE

Hydrolysis and Inhibition Profiles of β-Lactamases from Molecular Classes A to D with Doripenem, Imipenem, and Meropenem

Affinity of Doripenem and Comparators to Penicillin-Binding Proteins in Escherichia coli and Pseudomonas aeruginosa

Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007-09

Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

Interactions of Ceftobiprole with β-Lactamases from Molecular Classes A to D

Antistaphylococcal Activities of the New Fluoroquinolone JNJ-Q2

Synergistic Activity of Ceftobiprole and Vancomycin in a Rat Model of Infective Endocarditis Caused by Methicillin-Resistant and Glycopeptide-Intermediate Staphylococcus aureus

SME-3, a Novel Member of the Serratia marcescens SME Family of Carbapenem-Hydrolyzing β-Lactamases

In Vitro Activity of Ceftobiprole against Pathogens from Two Phase 3 Clinical Trials of Complicated Skin and Skin Structure Infections

Activities of Ceftobiprole and Other β-Lactams against Streptococcus pneumoniae Clinical Isolates from the United States with Defined Substitutions in Penicillin-Binding Proteins PBP 1a, PBP 2b, and PBP 2x

Genetic and Molecular Characterization of β-Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae with Unusually High Resistance to Ampicillin

Effects of Ceftobiprole and Oxacillin on mecA Expression in Methicillin-Resistant Staphylococcus aureus Clinical Isolates

Enterococcal virulence determinants may be involved in resistance to clinical therapy

Molecular characterisation of meticillin-resistant Staphylococcus aureus isolates from two ceftobiprole Phase 3 complicated skin and skin-structure infection clinical trials

High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of bla(ACT-1) beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe

Evaluation of the in vitro activities of ceftobiprole and comparators in staphylococcal colony or microtitre plate biofilm assays

The Spread of Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae to Upstate New York

Hydrolysis and Inhibition Profiles of ?-Lactamases from Molecular Classes A to D with Doripenem, Imipenem, and Meropenem

Activity of doripenem and comparator β-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbp1a, pbp2b and pbp2x

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone

The mouse intranasal challenge model for potency testing of whole-cell pertussis vaccines

Activities of Ceftobiprole and Other {szligbeta}-Lactams against Streptococcus pneumoniae Clinical Isolates from the United States with Defined Substitutions in Penicillin-Binding Proteins PBP 1a, PBP 2b, and PBP 2x

Activity of doripenem and comparator b-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbp1a, pbp2b and pbp2x

Activity of doripenem and comparator p-lactams against US clinical isolates of Streptococcus pneumoniae with defined mutations in the penicillin-binding domains of pbpla, pbp2b and pbp2x

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