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New biomarkers of Maillard reaction damage to proteins

Nephrology, dialysis, transplantation, 1996, Vol.11 (supp5), p.41-47

1996

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Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction

Diabetes (New York, N.Y.), 1994-05, Vol.43 (5), p.676-683

1994

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Aminoguanidine and the Effects of Modified LDL on Cultured Retinal Capillary Cells

Investigative ophthalmology & visual science, 2000-04, Vol.41 (5), p.1176

2000

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3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes

Diabetes (New York, N.Y.), 1994-09, Vol.43 (9), p.1152-1156

1994

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Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose

Biochemistry (Easton), 1995-03, Vol.34 (11), p.3702-3709

1995

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Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction

Diabetes (New York, N.Y.), 1994-05, Vol.43 (5), p.676-683

1994

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3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes

Diabetes (New York, N.Y.), 1994-09, Vol.43 (9), p.1152-1156

1994

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L-Arginine inhibits in vitro nonenzymatic glycation and advanced glycosylated end product formation of human serum albumin

Amino acids, 1996-01, Vol.11 (1), p.69-81

1996

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N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins

Biochemistry (Easton), 1995-08, Vol.34 (34), p.10872-10878

1995

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P 2–P 3 conformationally constrained ketoamide-based inhibitors of cathepsin K

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (15), p.3540-3546

2005

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Elements of diabetic nephropathy in a patient with GLUT2 deficiency

Molecular genetics and metabolism, 2005-12, Vol.86 (4), p.473-477

2005

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Potent and selective P 2–P 3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P 1′, P 1, and/or P 3 substitutions

Bioorganic & medicinal chemistry letters, 2004-10, Vol.14 (19), p.4897-4902

2004

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Design of small molecule ketoamide-based inhibitors of cathepsin K

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (3), p.719-722

2004

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A structural screening approach to ketoamide-based inhibitors of cathepsin K

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2209-2213

2005

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Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (4), p.978-983

2006

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Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2543-2546

2004

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ChemInform Abstract: Characterization of an Imidazolium Compound Formed by Reaction of Methylglyoxal and Nα-Hippuryllysine

ChemInform, 1996-03, Vol.27 (10), p.no-no

1996

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Cassette dosing: rapid in vivo assessment of pharmacokinetics

Pharmaceutical science & technology today, 1998-04, Vol.1 (1), p.12-18

1998

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N super( epsilon )-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins

Biochemistry (Easton), 1995-01, Vol.34 (34), p.10872-10878

1995

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Design, Synthesis, and Anaplastic Lymphoma Kinase (ALK) Inhibitory Activity for a Novel Series of 2,4,8,22-Tetraazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene Macrocycles

Journal of medicinal chemistry, 2012-01, Vol.55 (1), p.449-464

2012

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2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV

Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (23), p.5257-5261

2005

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Metabolism of Fructose-3-phosphate in the Diabetic Rat Lens

Archives of biochemistry and biophysics, 1995-04, Vol.318 (1), p.191-199

1995

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Characterization of an imidazolium compound formed by reaction of methylglyoxal and N α -hippuryllysine

J. Chem. Soc., Perkin Trans. 1, 1995 (22), p.2817-2818

1995

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New biomarkers of Maillard reaction damage to proteins

Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction

Aminoguanidine and the Effects of Modified LDL on Cultured Retinal Capillary Cells

3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes

Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose

Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction

3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes

L-Arginine inhibits in vitro nonenzymatic glycation and advanced glycosylated end product formation of human serum albumin

N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins

P 2–P 3 conformationally constrained ketoamide-based inhibitors of cathepsin K

Elements of diabetic nephropathy in a patient with GLUT2 deficiency

Potent and selective P 2–P 3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P 1′, P 1, and/or P 3 substitutions

Design of small molecule ketoamide-based inhibitors of cathepsin K

A structural screening approach to ketoamide-based inhibitors of cathepsin K

Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?

Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K

ChemInform Abstract: Characterization of an Imidazolium Compound Formed by Reaction of Methylglyoxal and Nα-Hippuryllysine

Cassette dosing: rapid in vivo assessment of pharmacokinetics

N super( epsilon )-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins

Design, Synthesis, and Anaplastic Lymphoma Kinase (ALK) Inhibitory Activity for a Novel Series of 2,4,8,22-Tetraazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene Macrocycles

2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV

Metabolism of Fructose-3-phosphate in the Diabetic Rat Lens

Characterization of an imidazolium compound formed by reaction of methylglyoxal and N α -hippuryllysine

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