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Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and in Vivo Activity

Journal of medicinal chemistry, 1996-01, Vol.39 (1), p.224-236

1996

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Quinoxaline N-oxide containing potent angiotensin II receptor antagonists: synthesis, biological properties, and structure-activity relationships

Journal of medicinal chemistry, 1993-08, Vol.36 (16), p.2335-2342

1993

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Phosphinyl acid-based bisubstrate analog inhibitors of ras farnesyl protein transferase

Journal of medicinal chemistry, 1995-02, Vol.38 (3), p.435-442

1995

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A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen

Rapid communications in mass spectrometry, 2009-06, Vol.23 (11), p.1579-1591

2009

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Purification of combinatorial libraries

Molecular diversity, 1998-01, Vol.4 (1), p.47-52

Weller, H N

1998

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High throughput analysis and purification in support of automated parallel synthesis

Molecular diversity, 1997, Vol.3 (1), p.61-70

1997

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Ketomethyldipeptides I. A new class of angiotensin converting enzyme inhibitors

Biochemical and biophysical research communications, 1984-10, Vol.124 (1), p.141-147

1984

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Ketomethyldipeptides II. Effect of modifications of the α-aminoketone portion on inhibition of angiotensin converting enzyme

Biochemical and biophysical research communications, 1984-10, Vol.124 (1), p.148-155

1984

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Design of conformationally constrained angiotensin-converting enzyme inhibitors

Biochemical and biophysical research communications, 1984-11, Vol.125 (1), p.82-89

1984

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Rapid vinyl shifts in spiro[4.4]polyenes: verification of the rate-determining step and the identity of the migrating group

Journal of organic chemistry, 1978-09, Vol.43 (19), p.3791-3792

1978

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Dihydropyrimidine angiotensin II receptor antagonists

Journal of medicinal chemistry, 1992-12, Vol.35 (25), p.4751-4763

1992

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Synthesis of N-alkyl-1,2,4-oxadiazinones as angiotensin-II (AT1) receptor antagonists

Heterocycles, 1993-05, Vol.36 (5), p.1027-1038

1993

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Pharmacology of novel imidazole alcohol inhibitors of primate renin

Journal of hypertension, 1989-04, Vol.7 Suppl 2 (2), p.S15-S19

1989

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Thermal rearrangements of spiro[4.4]nonapolyenes. Unusually rapid 1,5-vinyl migration

Journal of the American Chemical Society, 1977-01, Vol.99 (1), p.292-294

1977

Volltextzugriff (PDF)

Peptidomimetic Synthesis: A Novel, Highly Stereoselective Route to Substituted Freidinger Lactams

Journal of the American Chemical Society, 1994-03, Vol.116 (6), p.2348-2355

1994

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Design of tripeptide modeled inhibitors of angiotensin-converting enzyme: Studies on the role of the N-terminal acylamino group

Bioorganic chemistry, 1986-06, Vol.14 (2), p.148-156

1986

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Application of Lean Manufacturing Concepts to Drug Discovery: Rapid Analogue Library Synthesis

Journal of combinatorial chemistry, 2006-09, Vol.8 (5), p.664-669

2006

Volltextzugriff (PDF)

Cyclic (Hydroxyphosphinyl)Acyl Dipeptides: A New Class of Angiotensin Converting Enzyme Inhibitors

Journal of enzyme inhibition, 1988, Vol.2 (3), p.183-198

1988

Volltextzugriff (PDF)

PRESTRESSED CONCRETE PILES

PCI journal, 1962-10, Vol.7 (5), p.46-55

Weller, N. H. E.

1962

Volltextzugriff (PDF)

Benzothiadiazine dioxides: A new class of potent angiotensin-II (AT 1) receptor antagonists

Bioorganic & medicinal chemistry letters, 1992-09, Vol.2 (9), p.1115-1120

1992

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Studies on the synthesis of vitamin B-12. III

Journal of the American Chemical Society, 1983, Vol.105 (26), p.7719-7729

1983

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ChemInform Abstract: Peptidomimetic Synthesis: A Novel, Highly Stereoselective Route to Substituted Freidinger Lactams

ChemInform, 1994-07, Vol.25 (30), p.no-no

1994

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ChemInform Abstract: Synthesis of N-Alkyl-1,2,4-oxadiazinones as Angiotensin-II (AT1) Receptor Antagonists

ChemInform, 1993-08, Vol.24 (31), p.no-no

1993

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Conjunctivitis in dupilumab clinical trials

British journal of dermatology (1951), 2019-09, Vol.181 (3), p.459-473

2019

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Dupilumab with concomitant topical corticosteroid treatment in adults with atopic dermatitis with an inadequate response or intolerance to ciclosporin A or when this treatment is medically inadvisable: a placebo‐controlled, randomized phase III clinical trial (LIBERTY AD CAFÉ)

British journal of dermatology (1951), 2018-05, Vol.178 (5), p.1083-1101

2018

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Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and in Vivo Activity

Quinoxaline N-oxide containing potent angiotensin II receptor antagonists: synthesis, biological properties, and structure-activity relationships

Phosphinyl acid-based bisubstrate analog inhibitors of ras farnesyl protein transferase

A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen

Purification of combinatorial libraries

High throughput analysis and purification in support of automated parallel synthesis

Ketomethyldipeptides I. A new class of angiotensin converting enzyme inhibitors

Ketomethyldipeptides II. Effect of modifications of the α-aminoketone portion on inhibition of angiotensin converting enzyme

Design of conformationally constrained angiotensin-converting enzyme inhibitors

Rapid vinyl shifts in spiro[4.4]polyenes: verification of the rate-determining step and the identity of the migrating group

Dihydropyrimidine angiotensin II receptor antagonists

Synthesis of N-alkyl-1,2,4-oxadiazinones as angiotensin-II (AT1) receptor antagonists

Pharmacology of novel imidazole alcohol inhibitors of primate renin

Thermal rearrangements of spiro[4.4]nonapolyenes. Unusually rapid 1,5-vinyl migration

Peptidomimetic Synthesis: A Novel, Highly Stereoselective Route to Substituted Freidinger Lactams

Design of tripeptide modeled inhibitors of angiotensin-converting enzyme: Studies on the role of the N-terminal acylamino group

Application of Lean Manufacturing Concepts to Drug Discovery: Rapid Analogue Library Synthesis

Cyclic (Hydroxyphosphinyl)Acyl Dipeptides: A New Class of Angiotensin Converting Enzyme Inhibitors

PRESTRESSED CONCRETE PILES

Benzothiadiazine dioxides: A new class of potent angiotensin-II (AT 1) receptor antagonists

Studies on the synthesis of vitamin B-12. III

ChemInform Abstract: Peptidomimetic Synthesis: A Novel, Highly Stereoselective Route to Substituted Freidinger Lactams

ChemInform Abstract: Synthesis of N-Alkyl-1,2,4-oxadiazinones as Angiotensin-II (AT1) Receptor Antagonists

Conjunctivitis in dupilumab clinical trials

Dupilumab with concomitant topical corticosteroid treatment in adults with atopic dermatitis with an inadequate response or intolerance to ciclosporin A or when this treatment is medically inadvisable: a placebo‐controlled, randomized phase III clinical trial (LIBERTY AD CAFÉ)

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