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Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology

Clinical pharmacology and therapeutics, 2014-02, Vol.95 (2), p.154-167

2014

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Challenges in Implementing Genomic Medicine: The Mayo Clinic Center for Individualized Medicine

Clinical pharmacology and therapeutics, 2013-08, Vol.94 (2), p.204-206

2013

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Electronic Medical Record‐Integrated Pharmacogenomics and Related Clinical Decision Support Concepts

Clinical pharmacology and therapeutics, 2017-08, Vol.102 (2), p.254-264

2017

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Glycine and a Glycine Dehydrogenase ( ) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

Clinical pharmacology and therapeutics, 2011-01, Vol.89 (1), p.97-104

2011

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The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response

Clinical pharmacology and therapeutics, 2007-03, Vol.81 (3), p.328-345

2007

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SLC6A4 variation and citalopram response

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2009-04, Vol.150B (3), p.341-351

2009

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Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

The pharmacogenomics journal, 2013-10, Vol.13 (5), p.456-463

2013

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Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics

British journal of pharmacology, 2010-12, Vol.161 (7), p.1584-1598

2010

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CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment

JNCI : Journal of the National Cancer Institute, 2005-01, Vol.97 (1), p.30-39

2005

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Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes

Molecular psychiatry, 2004-02, Vol.9 (2), p.151-160

2004

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Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

Gut, 2001-11, Vol.49 (5), p.656-664

2001

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Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration

Clinical pharmacology and therapeutics, 2016-11, Vol.100 (5), p.423-426

2016

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The Impact of Pharmacogenomics on the Management of Cardiac Disease

Clinical pharmacology and therapeutics, 2011-10, Vol.90 (4), p.493-495

2011

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A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate–prednisone

Annals of oncology, 2018-02, Vol.29 (2), p.352-360

2018

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TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics

Molecular psychiatry, 2016-12, Vol.21 (12), p.1717-1725

2016

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Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate

Translational psychiatry, 2014, Vol.4 (10), p.e453-e453

2014

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Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization

The Journal of biological chemistry, 1994-05, Vol.269 (20), p.14835-14840

1994

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Human cytosolic sulfotransferase database mining: identification of seven novel genes and pseudogenes

The pharmacogenomics journal, 2004-01, Vol.4 (1), p.54-65

2004

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Human phenol sulfotransferases SULT1A2 and SULT1A1: Genetic polymorphisms, allozyme properties, and human liver genotype–phenotype correlations

Biochemical pharmacology, 1999-08, Vol.58 (4), p.605-616

1999

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New insights into the pharmacogenomics of antidepressant response from the GENDEP and STARD studies: rare variant analysis and high-density imputation

The pharmacogenomics journal, 2018-05, Vol.18 (3), p.413-421

2018

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Are patients willing to incur out-of-pocket costs for pharmacogenomic testing?

The pharmacogenomics journal, 2017-01, Vol.17 (1), p.1-3

2017

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Genetic diversity and function in the human cytosolic sulfotransferases

The pharmacogenomics journal, 2007-04, Vol.7 (2), p.133-143

2007

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Thiopurine methyltransferase polymorphic tandem repeat: Genotype-phenotype correlation analysis

Clinical pharmacology and therapeutics, 2000-08, Vol.68 (2), p.210-219

2000

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Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6‐mercaptopurine and azathioprine

British journal of clinical pharmacology, 1995-04, Vol.39 (4), p.456-459

1995

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Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects

Translational psychiatry, 2015-08, Vol.5 (8), p.e621-e621

2015

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Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology

Challenges in Implementing Genomic Medicine: The Mayo Clinic Center for Individualized Medicine

Electronic Medical Record‐Integrated Pharmacogenomics and Related Clinical Decision Support Concepts

Glycine and a Glycine Dehydrogenase ( ) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response

SLC6A4 variation and citalopram response

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics

CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment

Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes

Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration

The Impact of Pharmacogenomics on the Management of Cardiac Disease

A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate–prednisone

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics

Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate

Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization

Human cytosolic sulfotransferase database mining: identification of seven novel genes and pseudogenes

Human phenol sulfotransferases SULT1A2 and SULT1A1: Genetic polymorphisms, allozyme properties, and human liver genotype–phenotype correlations

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STARD studies: rare variant analysis and high-density imputation

Are patients willing to incur out-of-pocket costs for pharmacogenomic testing?

Genetic diversity and function in the human cytosolic sulfotransferases

Thiopurine methyltransferase polymorphic tandem repeat: Genotype-phenotype correlation analysis

Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6‐mercaptopurine and azathioprine

Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects

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