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Targeting Multiple Kinase Pathways in Leukemic Progenitors and Stem Cells Is Essential for Improved Treatment of Ph⁺ Leukemia in Mice

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (45), p.16870-16875

2006

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Crystallographic Structures of the Ligand-Binding Domains of the Androgen Receptor and Its T877A Mutant Complexed with the Natural Agonist Dihydrotestosterone

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.4904-4909

2001

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The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2004-12, Vol.14 (24), p.6107-6111

2004

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BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors

Blood, 2008-03, Vol.111 (5), p.2843-2853

2008

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Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients

Cancer research (Chicago, Ill.), 2009-09, Vol.69 (17), p.6889-6898

2009

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Molecular biomarkers in glaucoma

Investigative ophthalmology & visual science, 2013-01, Vol.54 (1), p.121-131

2013

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The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

Cell, 1991-06, Vol.65 (6), p.1063-1072

1991

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Wild-Type p53 Binds to the TATA-Binding Protein and Represses Transcription

Proceedings of the National Academy of Sciences - PNAS, 1992-12, Vol.89 (24), p.12028-12032

1992

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Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (2), p.271-276

2005

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Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

Molecular and Cellular Biology, 1995-01, Vol.15 (1), p.227-234

1995

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The Nonphosphorylated Form of RNA Polymerase II Preferentially Associates with the Preinitiation Complex

Proceedings of the National Academy of Sciences - PNAS, 1991-11, Vol.88 (22), p.10004-10008

1991

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Identification of a novel class of androgen receptor antagonists based on the bicyclic-1H-isoindole-1,3(2H)-dione nucleus

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (2), p.389-393

2005

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Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph super(+) leukemia in mice

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (45), p.16870-16875

2006

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Role of DNA-Dependent RNA Polymerase III in the Transcription of the tRNA and 5S RNA Genes

Proceedings of the National Academy of Sciences - PNAS, 1974-05, Vol.71 (5), p.1790-1794

1974

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Characterization of Hypoxia-Responsive Enhancer in the Human Erythropoietin Gene Shows Presence of Hypoxia-Inducible 120-Kd Nuclear DNA-Binding Protein in Erythropoietin-Producing and Nonproducing Cells

Blood, 1993-08, Vol.82 (3), p.704-711

1993

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Direct Interaction Between Adenovirus E1A Protein and the TATA Box Binding Transcription Factor IID

Proceedings of the National Academy of Sciences - PNAS, 1991-06, Vol.88 (12), p.5124-5128

1991

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Fyn and Src are Effectors of Oncogenic EGFR Signaling in Glioblastoma Patients

Cancer research (Chicago, Ill.), 2009-08, Vol.69 (17), p.6889-6898

2009

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Identification of novel functional inhibitors of 17β-hydroxysteroid dehydrogenase type III (17β-HSD3)

The Prostate, 2005-10, Vol.65 (2), p.159-170

2005

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Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells

Oncogene, 1995-05, Vol.10 (9), p.1763-1779

1995

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Promoter specificity and modulation of RNA polymerase II transcription

The FASEB journal, 1989-04, Vol.3 (6), p.1723-1733

1989

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Adenovirus E1A proteins interact with the cellular YY1 transcription factor

Journal of Virology, 1995-03, Vol.69 (3), p.1628-1636

1995

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Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes

The Journal of experimental medicine, 1987-06, Vol.165 (6), p.1581-1594

1987

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Quiescent Chronic Myelogenous Leukemia (CML) Cells Are Resistant to BCR-ABL Inhibitors but Preferentially Sensitive to BMS-214662, a Farnesyltransferase Inhibitor (FTI) with Unique Quiescent-Cell Selective Cytotoxicity

Blood, 2005-11, Vol.106 (11), p.1993-1993

2005

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Isolation and Partial Characterization of the Multiple Forms of Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerase in the Mouse Myeloma, MOPC 315

The Journal of biological chemistry, 1974-09, Vol.249 (18), p.5889-5897

1974

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Role of DNA-Dependent RNA Polymerases II and III in Transcription of the Adenovirus Genome Late in Productive Infection

Proceedings of the National Academy of Sciences - PNAS, 1974-09, Vol.71 (9), p.3426-3430

1974

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Targeting Multiple Kinase Pathways in Leukemic Progenitors and Stem Cells Is Essential for Improved Treatment of Ph⁺ Leukemia in Mice

Crystallographic Structures of the Ligand-Binding Domains of the Androgen Receptor and Its T877A Mutant Complexed with the Natural Agonist Dihydrotestosterone

The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonists

BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors

Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients

Molecular biomarkers in glaucoma

The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

Wild-Type p53 Binds to the TATA-Binding Protein and Represses Transcription

Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

The Nonphosphorylated Form of RNA Polymerase II Preferentially Associates with the Preinitiation Complex

Identification of a novel class of androgen receptor antagonists based on the bicyclic-1H-isoindole-1,3(2H)-dione nucleus

Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph super(+) leukemia in mice

Role of DNA-Dependent RNA Polymerase III in the Transcription of the tRNA and 5S RNA Genes

Characterization of Hypoxia-Responsive Enhancer in the Human Erythropoietin Gene Shows Presence of Hypoxia-Inducible 120-Kd Nuclear DNA-Binding Protein in Erythropoietin-Producing and Nonproducing Cells

Direct Interaction Between Adenovirus E1A Protein and the TATA Box Binding Transcription Factor IID

Fyn and Src are Effectors of Oncogenic EGFR Signaling in Glioblastoma Patients

Identification of novel functional inhibitors of 17β-hydroxysteroid dehydrogenase type III (17β-HSD3)

Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells

Promoter specificity and modulation of RNA polymerase II transcription

Adenovirus E1A proteins interact with the cellular YY1 transcription factor

Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes

Quiescent Chronic Myelogenous Leukemia (CML) Cells Are Resistant to BCR-ABL Inhibitors but Preferentially Sensitive to BMS-214662, a Farnesyltransferase Inhibitor (FTI) with Unique Quiescent-Cell Selective Cytotoxicity

Isolation and Partial Characterization of the Multiple Forms of Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerase in the Mouse Myeloma, MOPC 315

Role of DNA-Dependent RNA Polymerases II and III in Transcription of the Adenovirus Genome Late in Productive Infection

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