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Structure-Based Design of an Osteoclast-Selective, Nonpeptide Src Homology 2 Inhibitor with in vivo Antiresorptive Activity

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9373-9378

2000

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Bone-Targeted 2,6,9-Trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3067-3070

2003

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Novel Protein Kinase Inhibitors: SMART Drug Design Technology

BioTechniques, 2003-06, Vol.34 (sup), p.S2-S15

2003

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Regulation of Physiologic Actions of LRRK2: Focus on Autophagy

Neuro-degenerative diseases, 2012-01, Vol.10 (1-4), p.238-241

2012

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Selective Inhibition of Src SH2 by a Novel Thiol-Targeting Tricarbonyl-Modified Inhibitor and Mechanistic Analysis by 1H/ 13C NMR Spectroscopy

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1665-1669

2001

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Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds

Chemical biology & drug design, 2006-01, Vol.67 (1), p.46-57

2006

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Synthesis of iso-ddA, member of a novel class of anti-HIV agents

Tetrahedron letters, 1989, Vol.30 (46), p.6259-6262

1989

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Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

Science (American Association for the Advancement of Science), 1972-11, Vol.178 (4063), p.871-872

1972

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Synthesis of (S)-manoalide diol and the absolute configuration of natural manoalide

Tetrahedron letters, 1988, Vol.29 (20), p.2401-2404

1988

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Bone-Targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3063-3066

2003

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X-ray Structure of Citrate Bound to Src SH2 Leads to a High-Affinity, Bone-Targeted Src SH2 Inhibitor

Journal of medicinal chemistry, 2001-03, Vol.44 (5), p.660-663

2001

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Isolation and Identification of "Diazepam-Like" Compounds From Bovine Urine

Journal of natural products (Washington, D.C.), 1983-11, Vol.46 (6), p.852-861

1983

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Bone-Targeted pyrido[2,3- d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3071-3074

2003

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THE SYNTHESIS AND BIOLOGICAL TESTING OF 2, 2-DIMETHYLPENAM SULFONE

The Journal of Antibiotics, 1985, Vol.38(5), pp.677-679

1985

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Sozialpartnerschaft in der Gegenwart : Einflüsse der Technik und des technischen Wandels auf die Sozialpartnerschaft

Ferrum (Schaffhausen), 1993, Vol.65, p.67

Weigele, Manfred

1993

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Selective inhibition of Src SH2 by a novel thiol-targeting tricarbonyl-modified inhibitor and mechanistic analysis by (1)H/(13)C NMR spectroscopy

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1665-1669

2001

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Research Article: Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds

Chemical biology & drug design, 2006-01, Vol.67 (1), p.46-57

2006

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Novel protein kinase inhibitors: SMART drug design technology

BioTechniques, 2003-06, Vol.Suppl (JUN), p.2-13

2003

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Synthesis of DL-2-amino-4-(2-aminoethoxy)-trans-but-3-enoic acid

Journal of organic chemistry, 1978-09, Vol.43 (19), p.3713-3716

1978

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Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: Potent inhibitors of Src tyrosine kinase as novel antiresorptive agents: Recent advances in the design of kinase inhibitors as novel therapeutic agents

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (18), p.3071-3074

2003

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Bone-targeted 2,6,9-trisubstituted purines: Novel inhibitors of Src tyrosine kinase for the treatment of bone diseases: Recent advances in the design of kinase inhibitors as novel therapeutic agents

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (18), p.3067-3070

2003

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Bone-targeted Src kinase inhibitors: Novel pyrrolo- and pyrazolopyrimidine analogues: Recent advances in the design of kinase inhibitors as novel therapeutic agents

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (18), p.3063-3066

2003

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Synthesis and anti-HIV activity of isonucleosides

Journal of medicinal chemistry, 1992-06, Vol.35 (13), p.2347-2354

1992

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Preparation of 7-deoxyspectinomycin and 7-deoxy-8-epi-4(R)-dihydrospectinomycin

Journal of antibiotics, 1979, Vol.32 (4), p.418-419

1979

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Structure-Based Design of an Osteoclast-Selective, Nonpeptide Src Homology 2 Inhibitor with in vivo Antiresorptive Activity

Bone-Targeted 2,6,9-Trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases

Novel Protein Kinase Inhibitors: SMART Drug Design Technology

Regulation of Physiologic Actions of LRRK2: Focus on Autophagy

Selective Inhibition of Src SH2 by a Novel Thiol-Targeting Tricarbonyl-Modified Inhibitor and Mechanistic Analysis by 1H/ 13C NMR Spectroscopy

Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds

Synthesis of iso-ddA, member of a novel class of anti-HIV agents

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

Synthesis of (S)-manoalide diol and the absolute configuration of natural manoalide

SAR of Carbon-Linked, 2-Substituted Purines: Synthesis and Characterization of AP23451 as a novel Bone-Targeted Inhibitor of Src Tyrosine Kinase With In Vivo Anti-Resorptive Activity

Bone-Targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues

X-ray Structure of Citrate Bound to Src SH2 Leads to a High-Affinity, Bone-Targeted Src SH2 Inhibitor

Isolation and Identification of "Diazepam-Like" Compounds From Bovine Urine

Bone-Targeted pyrido[2,3- d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents

THE SYNTHESIS AND BIOLOGICAL TESTING OF 2, 2-DIMETHYLPENAM SULFONE

Sozialpartnerschaft in der Gegenwart : Einflüsse der Technik und des technischen Wandels auf die Sozialpartnerschaft

Selective inhibition of Src SH2 by a novel thiol-targeting tricarbonyl-modified inhibitor and mechanistic analysis by (1)H/(13)C NMR spectroscopy

Research Article: Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds

Novel protein kinase inhibitors: SMART drug design technology

Synthesis of DL-2-amino-4-(2-aminoethoxy)-trans-but-3-enoic acid

Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: Potent inhibitors of Src tyrosine kinase as novel antiresorptive agents: Recent advances in the design of kinase inhibitors as novel therapeutic agents

Bone-targeted 2,6,9-trisubstituted purines: Novel inhibitors of Src tyrosine kinase for the treatment of bone diseases: Recent advances in the design of kinase inhibitors as novel therapeutic agents

Bone-targeted Src kinase inhibitors: Novel pyrrolo- and pyrazolopyrimidine analogues: Recent advances in the design of kinase inhibitors as novel therapeutic agents

Synthesis and anti-HIV activity of isonucleosides

Preparation of 7-deoxyspectinomycin and 7-deoxy-8-epi-4(R)-dihydrospectinomycin

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