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Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys

Xenobiotica, 2017-12, Vol.47 (12), p.1090-1103

2017

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The species differences of intestinal drug absorption and first-pass metabolism between cynomolgus monkeys and humans

Journal of pharmaceutical sciences, 2009-11, Vol.98 (11), p.4343-4353

2009

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Efficacy and safety of the G protein‐coupled receptor 119 agonist DS‐8500a in Japanese type 2 diabetes mellitus patients with inadequate glycemic control on sitagliptin: A phase 2 randomized placebo‐controlled study

Journal of diabetes investigation, 2018-11, Vol.9 (6), p.1333-1341

2018

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Investigation of the Intestinal Permeability and First-Pass Metabolism of Drugs in Cynomolgus Monkeys Using Single-Pass Intestinal Perfusion

Biological and Pharmaceutical Bulletin, 2010/01/01, Vol.33(1), pp.111-116

2010

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Characterization of Gastrointestinal Drug Absorption in Cynomolgus Monkeys

Molecular pharmaceutics, 2008-03, Vol.5 (2), p.340-348

2008

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Efficacy and Safety of GPR119 Agonist DS-8500a in Japanese Patients with Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled, 12-Week Study

Advances in therapy, 2018-03, Vol.35 (3), p.367-381

2018

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Identification of Human Drug-Metabolizing Enzymes Involved in the Metabolism of SNI-2011

Biological and Pharmaceutical Bulletin, 2001, Vol.24(11), pp.1263-1266

2001

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Glucose-lowering effects and safety of DS-8500a, a G protein-coupled receptor 119 agonist, in Japanese patients with type 2 diabetes: results of a randomized, double-blind, placebo-controlled, parallel-group, multicenter, phase II study

BMJ open diabetes research & care, 2017-09, Vol.5 (1), p.e000424-e000424

2017

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Novel Isozyme-Specific Quantitation Method for Alpha-Amylases in Human Plasma Revealed Possible AMY2B Induction by Alpha-Amylase Inhibitor, CS-1036

Journal of proteomics & bioinformatics, 2017, Vol.10 (4)

2017

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The Species Differences of Intestinal Drug Absorption and First-Pass Metabolism between Cynomoigus Monkeys and Humans

Journal of pharmaceutical sciences, 2009, Vol.98 (11), p.4343-4353

2009

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Cytotoxic Effects of Several Hopanoids on Mouse Leukemia L1210 and P388 Cells

Biological and Pharmaceutical Bulletin, 1995/03/15, Vol.18(3), pp.421-423

1995

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Pharmacokinetics and metabolism of the novel muscarinic receptor agonist SNI-2011 in rats and dogs

Arzneimittel-Forschung, 2003-01, Vol.53 (1), p.26-33

2003

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Pharmacokinetics of SNI-2011. (2): Absorption, Excretion and Metabolism of 14C-SNI-2011 in Dogs

Yakubutsu dōtai = Xenobiotic metabolism and disposition, 2001, Vol.16 (6), p.553-557

2001

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Pharmacokinetics and Metabolism of Radiolabelled SNI-2011, a Novel Muscarinic Receptor Agonist, in Healthy Volunteers

Arzneimittel-Forschung, 2011-12, Vol.53 (2), p.80-86

2011

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Pharmacokinetics of SNI-2011. (1): Absorption, Distribution, Metabolism and Excretion of 14C-SNI-2011 in Rats

Yakubutsu dōtai = Xenobiotic metabolism and disposition, 2001, Vol.16 (6), p.537-552

2001

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Pharmacokinetics and metabolism of radiolabelled SNI-2011, a novel muscarinic receptor agonist, in healthy volunteers. Comprehensive understanding of absorption, metabolism and excretion using radiolabelled SNI-2011

Arzneimittel-Forschung, 2003, Vol.53 (2), p.80

2003

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Three Cases of Down Syndrome with Transient Abnormal Myelopoiesis who Underwent Liver Biopsy before Induction of Low-Dose Cytarabine

Acta medica Okayama, 2023-04, Vol.77 (2), p.215

2023

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Pediatric growing teratoma syndrome of the ovary: A case report and review of the literature

Medicine (Baltimore), 2020-09, Vol.99 (38), p.e22297-e22297

2020

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Neonatal hemochromatosis associated with rupture of esophageal varices

Pediatrics international, 2019-07, Vol.61 (7), p.735-737

2019

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UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses

Arteriosclerosis, thrombosis, and vascular biology, 2017-01, Vol.37 (1), p.66-74

2017

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Sorafenib treatment for papillary thyroid carcinoma with diffuse lung metastases in a child with autism spectrum disorder: a case report

BMC cancer, 2017-11, Vol.17 (1), p.775-775, Article 775

2017

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Suspected early onset of congenital Langerhans cell histiocytosis involving ectopic cervical thymus and mediastinal thymus, simultaneously

Pediatric blood & cancer, 2015-08, Vol.62 (8), p.1491-1492

2015

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Three Cases of Down Syndrome with Transient Abnormal Myelopoiesis who Underwent Liver Biopsy before Induction of Low-Dose Cytarabine

Acta medica Okayama, 2023, Vol.77 (2), p.215-220

2023

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Suspected early onset of congenital Langerhans cell histiocytosis involving ectopic cervical thymus and mediastinal thymus, simultaneously

Pediatric blood & cancer, 2015, Vol.62 (8), p.1491-1492

2015

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Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys

The species differences of intestinal drug absorption and first-pass metabolism between cynomolgus monkeys and humans

Efficacy and safety of the G protein‐coupled receptor 119 agonist DS‐8500a in Japanese type 2 diabetes mellitus patients with inadequate glycemic control on sitagliptin: A phase 2 randomized placebo‐controlled study

Investigation of the Intestinal Permeability and First-Pass Metabolism of Drugs in Cynomolgus Monkeys Using Single-Pass Intestinal Perfusion

Characterization of Gastrointestinal Drug Absorption in Cynomolgus Monkeys

Efficacy and Safety of GPR119 Agonist DS-8500a in Japanese Patients with Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled, 12-Week Study

Identification of Human Drug-Metabolizing Enzymes Involved in the Metabolism of SNI-2011

Glucose-lowering effects and safety of DS-8500a, a G protein-coupled receptor 119 agonist, in Japanese patients with type 2 diabetes: results of a randomized, double-blind, placebo-controlled, parallel-group, multicenter, phase II study

Novel Isozyme-Specific Quantitation Method for Alpha-Amylases in Human Plasma Revealed Possible AMY2B Induction by Alpha-Amylase Inhibitor, CS-1036

The Species Differences of Intestinal Drug Absorption and First-Pass Metabolism between Cynomoigus Monkeys and Humans

Cytotoxic Effects of Several Hopanoids on Mouse Leukemia L1210 and P388 Cells

Pharmacokinetics and metabolism of the novel muscarinic receptor agonist SNI-2011 in rats and dogs

Pharmacokinetics of SNI-2011. (2): Absorption, Excretion and Metabolism of 14C-SNI-2011 in Dogs

Pharmacokinetics and Metabolism of Radiolabelled SNI-2011, a Novel Muscarinic Receptor Agonist, in Healthy Volunteers

Pharmacokinetics of SNI-2011. (1): Absorption, Distribution, Metabolism and Excretion of 14C-SNI-2011 in Rats

Pharmacokinetics and metabolism of radiolabelled SNI-2011, a novel muscarinic receptor agonist, in healthy volunteers. Comprehensive understanding of absorption, metabolism and excretion using radiolabelled SNI-2011

Three Cases of Down Syndrome with Transient Abnormal Myelopoiesis who Underwent Liver Biopsy before Induction of Low-Dose Cytarabine

Pediatric growing teratoma syndrome of the ovary: A case report and review of the literature

Neonatal hemochromatosis associated with rupture of esophageal varices

UVB Exposure Prevents Atherosclerosis by Regulating Immunoinflammatory Responses

Sorafenib treatment for papillary thyroid carcinoma with diffuse lung metastases in a child with autism spectrum disorder: a case report

Suspected early onset of congenital Langerhans cell histiocytosis involving ectopic cervical thymus and mediastinal thymus, simultaneously

Three Cases of Down Syndrome with Transient Abnormal Myelopoiesis who Underwent Liver Biopsy before Induction of Low-Dose Cytarabine

Suspected early onset of congenital Langerhans cell histiocytosis involving ectopic cervical thymus and mediastinal thymus, simultaneously

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