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Racemic and chiral sulfoxides as potential prodrugs of the COX-2 inhibitors Vioxx ® and Arcoxia

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3209-3212

2006

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Interview with Graham Warrellow by Isaac Bruce

Future medicinal chemistry, 2012-06, Vol.4 (9), p.1047

Warrellow, Graham

2012

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Interview with Graham Warrellow

Future medicinal chemistry, 2012-06, Vol.4 (9), p.1047-1051

Warrellow, Graham

2012

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Squaric acid derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2002-04, Vol.12 (7), p.1051-1054

2002

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Discovery and evaluation of N-(triazin-1,3,5-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1591-1594

2002

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PDE 4 inhibitors: the use of molecular cloning in the design and development of novel drugs

Drug discovery today, 1997-03, Vol.2 (3), p.89-101

1997

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Dehydrophenylalanine derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (5), p.805-808

2003

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N-(Pyrimidin-4-yl) and N-(Pyridin-2-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1595-1598

2002

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Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization

Drug metabolism and disposition, 2001-03, Vol.29 (3), p.232

2001

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Discovery and evaluation of potent, cysteine-based α4β1 integrin antagonists

Bioorganic & medicinal chemistry letters, 2000-05, Vol.10 (9), p.993-995

2000

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Racemic and chiral sulfoxides as potential prodrugs of 4-pyrone COX-2 inhibitors

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3605-3608

2006

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Discovery and Characterization of 4‘-(2-Furyl)-N-pyridin-3-yl-4,5‘-bipyrimidin-2‘-amine (LAS38096), a Potent, Selective, and Efficacious A2B Adenosine Receptor Antagonist

Journal of medicinal chemistry, 2007-05, Vol.50 (11), p.2732-2736

2007

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Synthesis and Structure−Activity Relationships of Novel Histamine H 1 Antagonists: Indolylpiperidinyl Benzoic Acid Derivatives

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6326-6337

2004

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Racemic and chiral sulfoxides as potential prodrugs of the COX-2 inhibitors Vioxx super([registered]) and Arcoxia super([registered])

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3209-3212

2006

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Synthesis and structure–activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H 1 antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.1165-1167

2005

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Synthesis and structure-activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H1 antagonists

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.1165-1167

2005

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Discovery and Characterization of 4‘-(2-Furyl)- N -pyridin-3-yl-4,5‘-bipyrimidin-2‘-amine (LAS38096), a Potent, Selective, and Efficacious A 2B Adenosine Receptor Antagonist

Journal of medicinal chemistry, 2007-05, Vol.50 (11), p.2732-2736

2007

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Vinyl azides in heterocyclic synthesis. Part 10. Synthesis of the isoindolobenzazepine alkaloid lennoxamine

Journal of the Chemical Society, Perkin Transactions 1, 1990 (11), p.2929

1990

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Interview with Graham Warrellow by Isaac Bruce

Future medicinal chemistry, 2012, Vol.4 (9), p.1047-1051

Warrellow, Graham

2012

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Discovery and evaluation of potent, tyrosine-based α4β1 integrin antagonists

Bioorganic & medicinal chemistry letters, 2000-05, Vol.10 (9), p.997-999

2000

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Synthesis and .alpha.2-adrenoceptor antagonist activity of some disulfonamidobenzoquinolizines

Journal of medicinal chemistry, 1989-01, Vol.32 (1), p.179-182

1989

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Synthesis and Structure−Activity Relationships of Novel Histamine H1 Antagonists: Indolylpiperidinyl Benzoic Acid Derivatives

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6326-6337

2004

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Vinyl azides in heterocyclic synthesis. Part 4. Thermal and photochemical decomposition of azidocinnamates containing ortho-cycloalkenyl substituents

Journal of the Chemical Society, Perkin Transactions 1, 1986, p.1123

1986

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Vinyl azides in heterocyclic synthesis. Part 5. Thermal and photochemical decomposition of azidocinnamates containing ortho-cycloalkylidene substituents

Journal of the Chemical Society, Perkin Transactions 1, 1987, p.913

1987

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Pharmacological characterization of the neonatally sensitized rabbit model and effects of a novel phosphodiesterase (PDE) 4 inhibitor

Journal of pharmacy and pharmacology, 1998-09, Vol.50 (S9), p.69-69

1998

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Racemic and chiral sulfoxides as potential prodrugs of the COX-2 inhibitors Vioxx ® and Arcoxia

Interview with Graham Warrellow by Isaac Bruce

Interview with Graham Warrellow

Squaric acid derivatives as VLA-4 integrin antagonists

Discovery and evaluation of N-(triazin-1,3,5-yl) phenylalanine derivatives as VLA-4 integrin antagonists

PDE 4 inhibitors: the use of molecular cloning in the design and development of novel drugs

Dehydrophenylalanine derivatives as VLA-4 integrin antagonists

N-(Pyrimidin-4-yl) and N-(Pyridin-2-yl) phenylalanine derivatives as VLA-4 integrin antagonists

Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization

Discovery and evaluation of potent, cysteine-based α4β1 integrin antagonists

Racemic and chiral sulfoxides as potential prodrugs of 4-pyrone COX-2 inhibitors

Discovery and Characterization of 4‘-(2-Furyl)-N-pyridin-3-yl-4,5‘-bipyrimidin-2‘-amine (LAS38096), a Potent, Selective, and Efficacious A2B Adenosine Receptor Antagonist

Synthesis and Structure−Activity Relationships of Novel Histamine H 1 Antagonists: Indolylpiperidinyl Benzoic Acid Derivatives

Racemic and chiral sulfoxides as potential prodrugs of the COX-2 inhibitors Vioxx super([registered]) and Arcoxia super([registered])

Synthesis and structure–activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H 1 antagonists

Synthesis and structure-activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H1 antagonists

Discovery and Characterization of 4‘-(2-Furyl)- N -pyridin-3-yl-4,5‘-bipyrimidin-2‘-amine (LAS38096), a Potent, Selective, and Efficacious A 2B Adenosine Receptor Antagonist

Vinyl azides in heterocyclic synthesis. Part 10. Synthesis of the isoindolobenzazepine alkaloid lennoxamine

Interview with Graham Warrellow by Isaac Bruce

Discovery and evaluation of potent, tyrosine-based α4β1 integrin antagonists

Synthesis and .alpha.2-adrenoceptor antagonist activity of some disulfonamidobenzoquinolizines

Synthesis and Structure−Activity Relationships of Novel Histamine H1 Antagonists: Indolylpiperidinyl Benzoic Acid Derivatives

Vinyl azides in heterocyclic synthesis. Part 4. Thermal and photochemical decomposition of azidocinnamates containing ortho-cycloalkenyl substituents

Vinyl azides in heterocyclic synthesis. Part 5. Thermal and photochemical decomposition of azidocinnamates containing ortho-cycloalkylidene substituents

Pharmacological characterization of the neonatally sensitized rabbit model and effects of a novel phosphodiesterase (PDE) 4 inhibitor

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