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A phase 1 ascending dose study of a subcutaneously administered factor IXa inhibitor and its active control agent

Journal of thrombosis and haemostasis, 2012-07, Vol.10 (7), p.1303-1311

2012

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Importance of the Organ-Independent Elimination of Cisatracurium

Anesthesia and analgesia, 1996-11, Vol.83 (5), p.1065-1071

1996

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Pharmacokinetics of RheothRx Injection in Healthy Male Volunteers

Journal of pharmaceutical sciences, 1997-07, Vol.86 (7), p.808-812

1997

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Bidirectional interaction of valproate and lamotrigine in healthy subjects

Clinical pharmacology and therapeutics, 1996-08, Vol.60 (2), p.145-156

1996

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The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study

Journal of thrombosis and thrombolysis, 2014-10, Vol.38 (3), p.275-284

2014

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Dose Selection for a Direct and Selective Factor IXa Inhibitor and its Complementary Reversal Agent: Translating Pharmacokinetic and Pharmacodynamic Properties of the REG1 System to Clinical Trial Design

Journal of thrombosis and thrombolysis, 2011-07, Vol.32 (1), p.21-31

2011

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Pharmacokinetics and safety of lamotrigine (Lamictal®) in patients with epilepsy

Epilepsy research, 1991-11, Vol.10 (2), p.191-200

1991

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Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors

Journal of clinical oncology, 1994-09, Vol.12 (9), p.1754-1763

1994

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Pharmacokinetics and Pharmacodynamics of Doxacurium in Young and Elderly Patients During Isoflurane Anesthesia

Anesthesia and analgesia, 1990-11, Vol.71 (5), p.498-502

1990

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THE PHARMACOKINETICS OF 1954U89, 1, 3-DIAMINO-7-(1-ETHYLPROPYL)-8-METHYL-7H-PYRROLO-(3, 2-f )QUINAZOLINE, IN DOGS AND RATS AFTER INTRAVENOUS AND ORAL ADMINISTRATION

Biopharmaceutics & drug disposition, 1997-07, Vol.18 (5), p.433-442

1997

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Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy

European heart journal, 2011-10, Vol.32 (19), p.2412-2419

2011

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Pharmacokinetics of Oral and Transdermal Triprolidine

Journal of clinical pharmacology, 1990-06, Vol.30 (6), p.572-575

1990

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A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease

American journal of hematology, 2012-11, Vol.87 (11), p.1017-1021

2012

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Antipyrine kinetics following partial blood exchange with Fluosol-DA in the rat

Journal of pharmacy and pharmacology, 1986-12, Vol.38 (12), p.883-887

1986

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Separation and quantitation of theophylline and paraxanthine by reversed-phase liquid chromatography

Clinical chemistry (Baltimore, Md.), 1980-03, Vol.26 (3), p.524

1980

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Crisnatol mesylate : phase I dose escalation by extending infusion duration

Investigational new drugs, 1991-02, Vol.9 (1), p.41-47

1991

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Factors Associated With Nephrotoxicity and Clinical Outcome in Patients Receiving Amikacin

Journal of clinical pharmacology, 1986-02, Vol.26 (2), p.79-86

1986

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High-pressure liquid chromatographic assay for chloramphenicol, chloramphenicol-3-monosuccinate, and chloramphenicol-1-monosuccinate

Journal of pharmaceutical sciences, 1980-08, Vol.69 (8), p.909-912

1980

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Correlation of predicted versus measured creatinine clearance values in burn patients

American journal of hospital pharmacy, 1978-06, Vol.35 (6), p.717

1978

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Pharmacokinetics of intravenous chloramphenicol sodium succinate in adult patients with normal renal and hepatic function

Journal of pharmacokinetics and biopharmaceutics, 1982-12, Vol.10 (6), p.601-614

1982

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Influence of range of renal function and liver disease on predictability of creatinine clearance

Clinical pharmacology and therapeutics, 1981-04, Vol.29 (4), p.516-521

1981

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Kinetic model for gentamicin dosing with the use of individual patient parameters

Clinical pharmacology and therapeutics, 1977-03, Vol.21 (3), p.362-369

1977

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Variable first-pass elimination of propranolol following single and multiple oral doses in hypertensive patients

European journal of drug metabolism and pharmacokinetics, 1982-01, Vol.7 (3), p.183-189

1982

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High-performance liquid chromatographic determination of carbaryl and 1-naphthol in biological fluids

Journal of chromatography, 1982-09, Vol.246 (1), p.89

1982

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Automated dissolution testing of combination drug product using high-pressure liquid chromatography

Journal of pharmaceutical sciences, 1981-07, Vol.70 (7), p.764-767

1981

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A phase 1 ascending dose study of a subcutaneously administered factor IXa inhibitor and its active control agent

Importance of the Organ-Independent Elimination of Cisatracurium

Pharmacokinetics of RheothRx Injection in Healthy Male Volunteers

Bidirectional interaction of valproate and lamotrigine in healthy subjects

The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study

Dose Selection for a Direct and Selective Factor IXa Inhibitor and its Complementary Reversal Agent: Translating Pharmacokinetic and Pharmacodynamic Properties of the REG1 System to Clinical Trial Design

Pharmacokinetics and safety of lamotrigine (Lamictal®) in patients with epilepsy

Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors

Pharmacokinetics and Pharmacodynamics of Doxacurium in Young and Elderly Patients During Isoflurane Anesthesia

THE PHARMACOKINETICS OF 1954U89, 1, 3-DIAMINO-7-(1-ETHYLPROPYL)-8-METHYL-7H-PYRROLO-(3, 2-f )QUINAZOLINE, IN DOGS AND RATS AFTER INTRAVENOUS AND ORAL ADMINISTRATION

Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy

Pharmacokinetics of Oral and Transdermal Triprolidine

A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease

Antipyrine kinetics following partial blood exchange with Fluosol-DA in the rat

Separation and quantitation of theophylline and paraxanthine by reversed-phase liquid chromatography

Crisnatol mesylate : phase I dose escalation by extending infusion duration

Factors Associated With Nephrotoxicity and Clinical Outcome in Patients Receiving Amikacin

High-pressure liquid chromatographic assay for chloramphenicol, chloramphenicol-3-monosuccinate, and chloramphenicol-1-monosuccinate

Correlation of predicted versus measured creatinine clearance values in burn patients

Pharmacokinetics of intravenous chloramphenicol sodium succinate in adult patients with normal renal and hepatic function

Influence of range of renal function and liver disease on predictability of creatinine clearance

Kinetic model for gentamicin dosing with the use of individual patient parameters

Variable first-pass elimination of propranolol following single and multiple oral doses in hypertensive patients

High-performance liquid chromatographic determination of carbaryl and 1-naphthol in biological fluids

Automated dissolution testing of combination drug product using high-pressure liquid chromatography

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