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Synthesis of Allene Substituted Nipecotic Acids by Allenylation of Terminal Alkynes

Journal of organic chemistry, 2017-08, Vol.82 (16), p.8371-8388

2017

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Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity—An in vitro structure-activity analysis

Toxicology letters, 2018-09, Vol.293, p.157-166

2018

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Drivers of Change in National Disaster Governance under the Hyogo Framework for Action

Politics and governance, 2020-12, Vol.8 (4), p.256-269

Wanner, Maximilian S. T.

2020

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Simultaneous LC-ESI-MS/MS Quantification of Levosimendan and Its Metabolites for Therapeutic Drug Monitoring of Cardiac Surgery Patients

Pharmaceutics, 2022-07, Vol.14 (7), p.1454

2022

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A Library Screening Strategy Combining the Concepts of MS Binding Assays and Affinity Selection Mass Spectrometry

Frontiers in chemistry, 2019-10, Vol.7, p.665-665

2019

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Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1–mGAT4

European journal of medicinal chemistry, 2008-11, Vol.43 (11), p.2404-2411

2008

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MS Binding Assays for the Three Monoamine Transporters Using the Triple Reuptake Inhibitor (1R,3S)-Indatraline as Native Marker

ChemMedChem, 2015-06, Vol.10 (6), p.1027-1039

2015

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The Environment Shapes the Inner Vestibule of LeuT

PLoS computational biology, 2016-11, Vol.12 (11), p.e1005197-e1005197

2016

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Serum concentrations of levosimendan and its metabolites OR-1855 and OR-1896 in cardiac surgery patients with cardiopulmonary bypass

Frontiers in cardiovascular medicine, 2024-08, Vol.11, p.1406338

2024

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Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores

PloS one, 2016-02, Vol.11 (2), p.e0148608-e0148608

2016

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MS-Binding Assays: Kinetic, Saturation, and Competitive Experiments Based on Quantitation of Bound Marker as Exemplified by the GABA Transporter mGAT1

ChemMedChem, 2006-02, Vol.1 (2), p.208-217

2006

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Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors γ-aminobutyric acid transporter 1

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1232-1245

2019

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Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism

Nature structural & molecular biology, 2023-07, Vol.30 (7), p.1023-1032

2023

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Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4

European journal of pharmacology, 2005-09, Vol.519 (1-2), p.43-47

2005

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New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling

Current computer-aided drug design, 2019-01, Vol.15 (1), p.104-109

2019

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Benocyclidine (BTCP) as Non‐labelled Reporter Ligand for MS Binding Assays for the PCP Ion Channel Binding Site of the Desensitized Torpedo Nicotinic Acetylcholine Receptor (nAChR)

ChemMedChem, 2023-05, Vol.18 (10), p.e202300048-n/a

2023

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Application of an Ugi type reaction to an N-silyl-4,4-disubstituted 1,4-dihydropyridine

Tetrahedron, 2009-12, Vol.65 (50), p.10463-10469

2009

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Combination of MS Binding Assays and affinity selection mass spectrometry for screening of structurally homogenous libraries as exemplified for a focused oxime library addressing the neuronal GABA transporter 1

European journal of medicinal chemistry, 2020-11, Vol.206, p.112598-112598, Article 112598

2020

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Novel Allosteric Ligands of γ‑Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries

Journal of medicinal chemistry, 2018-11, Vol.61 (22), p.10310-10332

2018

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MS binding assays for GlyT1 based on Org24598 as nonlabelled reporter ligand

Neuropharmacology, 2019-12, Vol.161, p.107561-107561, Article 107561

2019

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Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor

Toxicology letters, 2024-04, Vol.394, p.23-31

2024

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Screening for New Inhibitors of Glycine Transporter 1 and 2 by Means of MS Binding Assays

ChemMedChem, 2021-10, Vol.16 (19), p.3094-3104

2021

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Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (12), p.3668-3687

2018

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Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a cis-alkene spacer as GABA uptake inhibitors

Bioorganic & medicinal chemistry, 2019-03, Vol.27 (5), p.822-831

2019

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Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a trans-alkene spacer as potent GABA uptake inhibitors

Bioorganic & medicinal chemistry, 2018-12, Vol.26 (22), p.5944-5961

2018

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Synthesis of Allene Substituted Nipecotic Acids by Allenylation of Terminal Alkynes

Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity—An in vitro structure-activity analysis

Drivers of Change in National Disaster Governance under the Hyogo Framework for Action

Simultaneous LC-ESI-MS/MS Quantification of Levosimendan and Its Metabolites for Therapeutic Drug Monitoring of Cardiac Surgery Patients

A Library Screening Strategy Combining the Concepts of MS Binding Assays and Affinity Selection Mass Spectrometry

Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1–mGAT4

MS Binding Assays for the Three Monoamine Transporters Using the Triple Reuptake Inhibitor (1R,3S)-Indatraline as Native Marker

The Environment Shapes the Inner Vestibule of LeuT

Serum concentrations of levosimendan and its metabolites OR-1855 and OR-1896 in cardiac surgery patients with cardiopulmonary bypass

Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores

MS-Binding Assays: Kinetic, Saturation, and Competitive Experiments Based on Quantitation of Bound Marker as Exemplified by the GABA Transporter mGAT1

Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors γ-aminobutyric acid transporter 1

Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism

Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4

New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling

Benocyclidine (BTCP) as Non‐labelled Reporter Ligand for MS Binding Assays for the PCP Ion Channel Binding Site of the Desensitized Torpedo Nicotinic Acetylcholine Receptor (nAChR)

Application of an Ugi type reaction to an N-silyl-4,4-disubstituted 1,4-dihydropyridine

Combination of MS Binding Assays and affinity selection mass spectrometry for screening of structurally homogenous libraries as exemplified for a focused oxime library addressing the neuronal GABA transporter 1

Novel Allosteric Ligands of γ‑Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries

MS binding assays for GlyT1 based on Org24598 as nonlabelled reporter ligand

Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor

Screening for New Inhibitors of Glycine Transporter 1 and 2 by Means of MS Binding Assays

Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors

Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a cis-alkene spacer as GABA uptake inhibitors

Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a trans-alkene spacer as potent GABA uptake inhibitors

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