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Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (21), p.10557-10562

2019

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Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Nature communications, 2022-11, Vol.13 (1), p.7131-7131, Article 7131

2022

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A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2

Frontiers in pharmacology, 2021-06, Vol.12, p.685308-685308

2021

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Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Communications chemistry, 2024-04, Vol.7 (1), p.84-84, Article 84

2024

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Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors

Accounts of chemical research, 2021-02, Vol.54 (4), p.930-939

2021

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A Synthetic ERR Agonist Alleviates Metabolic Syndrome

The Journal of pharmacology and experimental therapeutics, 2024-02, Vol.388 (2), p.232

2024

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Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold

Biochimica et biophysica acta. General subjects, 2020-06, Vol.1864 (6), p.129546-129546, Article 129546

2020

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Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804

Biochemistry (Easton), 2009-07, Vol.48 (27), p.6402-6411

2009

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Identification and structure–activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus

Bioorganic & medicinal chemistry letters, 2023-06, Vol.89, p.129301-129301, Article 129301

2023

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Discovery and Characterization of Atropisomer PH-797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate

ChemMedChem, 2012-02, Vol.7 (2), p.273-280

2012

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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

Circulation (New York, N.Y.), 2024-01, Vol.149 (3), p.227

2024

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Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

ACS chemical biology, 2023-04, Vol.18 (4), p.756-771

2023

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GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain

The Journal of pharmacology and experimental therapeutics, 2020-11, Vol.375 (2), p.367

2020

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Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

European journal of medicinal chemistry, 2023-10, Vol.258, p.115582, Article 115582

2023

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Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney

The American journal of pathology, 2023-12, Vol.193 (12), p.1969-1987

2023

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Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.6205-6219

2017

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Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria

Journal of chemical information and modeling, 2020-06, Vol.60 (6), p.2838-2847

2020

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A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells

ACS chemical biology, 2020-09, Vol.15 (9), p.2338-2345

2020

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Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism

ACS chemical neuroscience, 2016-02, Vol.7 (2), p.143-148

2016

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The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein

Protein science, 2017-08, Vol.26 (8), p.1595-1608

2017

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Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5851-5856

2009

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AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii

ACS infectious diseases, 2024-06, Vol.10 (6), p.2239-2249

2024

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Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump

ACS infectious diseases, 2017-01, Vol.3 (1), p.89-98

2017

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Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa

A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors

A Synthetic ERR Agonist Alleviates Metabolic Syndrome

Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold

Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804

Identification and structure–activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus

Discovery and Characterization of Atropisomer PH-797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate

Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain

Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney

Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli

Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria

International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023

A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells

Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism

The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein

Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase

AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii

Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump

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