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CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape

Cell reports (Cambridge), 2016-04, Vol.15 (3), p.481-489

2016

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HIV drug resistance against strand transfer integrase inhibitors

Retrovirology, 2017-06, Vol.14 (1), p.36-36, Article 36

2017

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Clinical benefit of dolutegravir in HIV-1 management related to the high genetic barrier to drug resistance

Virus research, 2017-07, Vol.239, p.1-9

2017

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Cellular and molecular mechanisms involved in the establishment of HIV-1 latency

Retrovirology, 2013-02, Vol.10 (1), p.11-11, Article 11

2013

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The role of unintegrated DNA in HIV infection

Retrovirology, 2011-07, Vol.8 (1), p.52-52, Article 52

2011

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Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

Journal of Virology, 2012-03, Vol.86 (5), p.2696-2705

2012

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Early HIV treatment to forestall drug resistance

The Lancet infectious diseases, 2016-05, Vol.16 (5), p.512-513

Wainberg, Mark A

2016

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Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence

Viruses, 2015-07, Vol.7 (7), p.3703-3718

2015

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Evaluation of Sofosbuvir (β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine) as an inhibitor of Dengue virus replication

Scientific reports, 2017-07, Vol.7 (1), p.6345-11, Article 6345

2017

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Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors

Journal of antimicrobial chemotherapy, 2017-03, Vol.72 (3), p.727-734

2017

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RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I

Journal of Virology, 2011-02, Vol.85 (3), p.1224-1236

2011

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Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase

Journal of virology, 2015-03, Vol.89 (6), p.3163-3175

2015

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Antiviral Drug Resistance and the Need for Development of New HIV-1 Reverse Transcriptase Inhibitors

Antimicrobial Agents and Chemotherapy, 2012-10, Vol.56 (10), p.5000-5008

2012

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Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors

Journal of antimicrobial chemotherapy, 2016-07, Vol.71 (7), p.1948-1953

2016

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High Rates of Forward Transmission Events after Acute/Early HIV-1 Infection

The Journal of infectious diseases, 2007-04, Vol.195 (7), p.951-959

2007

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Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

Retrovirology, 2017-10, Vol.14 (1), p.47-47, Article 47

2017

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Compensation by the E138K Mutation in HIV-1 Reverse Transcriptase for Deficits in Viral Replication Capacity and Enzyme Processivity Associated with the M184I/V Mutations

Journal of Virology, 2011-11, Vol.85 (21), p.11300-11308

2011

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Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.600-608

2016

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Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase

Antimicrobial Agents and Chemotherapy, 2013-12, Vol.57 (12), p.6223-6235

2013

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Novel therapeutic strategies targeting HIV integrase

BMC medicine, 2012-04, Vol.10 (1), p.34-34, Article 34

2012

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The Viral Protein Tat Can Inhibit the Establishment of HIV-1 Latency

Journal of Virology, 2012-03, Vol.86 (6), p.3253-3263

2012

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Is resistance to dolutegravir possible when this drug is used in first-line therapy?

Viruses, 2014-08, Vol.6 (9), p.3377-3385

2014

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Tetherin restricts direct cell-to-cell infection of HIV-1

Retrovirology, 2010-12, Vol.7 (1), p.115-115, Article 115

2010

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Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and Their Interactions with the M184I Mutation on Defining Patterns of Resistance to Nonnucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine

Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3100-3109

2013

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Productive Entry of HIV-1 during Cell-to-Cell Transmission via Dynamin-Dependent Endocytosis

Journal of Virology, 2013-07, Vol.87 (14), p.8110-8123

2013

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CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape

HIV drug resistance against strand transfer integrase inhibitors

Clinical benefit of dolutegravir in HIV-1 management related to the high genetic barrier to drug resistance

Cellular and molecular mechanisms involved in the establishment of HIV-1 latency

The role of unintegrated DNA in HIV infection

Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

Early HIV treatment to forestall drug resistance

Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence

Evaluation of Sofosbuvir (β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine) as an inhibitor of Dengue virus replication

Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I

Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase

Antiviral Drug Resistance and the Need for Development of New HIV-1 Reverse Transcriptase Inhibitors

Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors

High Rates of Forward Transmission Events after Acute/Early HIV-1 Infection

Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

Compensation by the E138K Mutation in HIV-1 Reverse Transcriptase for Deficits in Viral Replication Capacity and Enzyme Processivity Associated with the M184I/V Mutations

Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase

Novel therapeutic strategies targeting HIV integrase

The Viral Protein Tat Can Inhibit the Establishment of HIV-1 Latency

Is resistance to dolutegravir possible when this drug is used in first-line therapy?

Tetherin restricts direct cell-to-cell infection of HIV-1

Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and Their Interactions with the M184I Mutation on Defining Patterns of Resistance to Nonnucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine

Productive Entry of HIV-1 during Cell-to-Cell Transmission via Dynamin-Dependent Endocytosis

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