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Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy

Human cell : official journal of Human Cell Research Society, 2024-10, Vol.38 (1), p.9, Article 9

2024

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P1372: NON‐MYELOTOXIC CHEMICALS AS A PREPARATORY REGIMEN FOR HEMATOPOIETIC STEM CELL GENE THERAPY

HemaSphere, 2023-08, Vol.7 (S3), p.e6316019-n/a

2023

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Recombination-activating gene 1 ( Rag1 )–deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome

Journal of allergy and clinical immunology, 2014-04, Vol.133 (4), p.1116-1123

2014

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Lentiviral hematopoietic stem cell gene therapy in inherited metabolic disorders

Human gene therapy, 2014-10, Vol.25 (10), p.862-865

Wagemaker, Gerard

2014

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Lentiviral Hematopoietic Stem Cell Gene Therapy Corrects Murine Pompe Disease

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.1014-1025

2020

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In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice

PloS one, 2013-04, Vol.8 (4), p.e60680-e60680

2013

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Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype

Blood, 2010-07, Vol.115 (26), p.5329-5337

2010

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Anniversary issue on gene and cell therapy in the Netherlands

Human gene therapy, 2014-10, Vol.25 (10), p.857-858

Wagemaker, Gerard

2014

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Mobilization of hepatic mesenchymal stem cells from human liver grafts

Liver transplantation, 2011-05, Vol.17 (5), p.596-609

2011

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Correction of Murine SCID-X1 by Lentiviral Gene Therapy Using a Codon-optimized IL2RG Gene and Minimal Pretransplant Conditioning

Molecular therapy, 2011-10, Vol.19 (10), p.1867-1877

2011

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Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE

Molecular therapy. Methods & clinical development, 2018-03, Vol.8 (C), p.152-165

2018

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5-Androstene-3β,17β-diol Promotes Recovery of Immature Hematopoietic Cells Following Myelosuppressive Radiation and Synergizes With Thrombopoietin

International journal of radiation oncology, biology, physics, 2012-11, Vol.84 (3), p.e401-e407

2012

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Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Immune and Lysoso- mal Enzyme Deficiencies

Cellular therapy and transplantation, 2016-12, Vol.5 (4), p.56-62

Wagemaker, Gerard

2016

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Chapter 6: Cell and cell system responses: Heterogeneity of radiation sensitivity of hemopoietic stem cell subsets

Stem cells (Dayton, Ohio), 1995-05, Vol.13 (S1), p.257-260

Wagemaker, Gerard

1995

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Human mesenchymal stem cells support B-cell and T-cell differentiation of cord blood CD34+ cells under optimized conditions

Experimental hematology, 2017-09, Vol.53, p.S135-S135

2017

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Long-Term Effects of Irradiation Before Adulthood on Reproductive Function in the Male Rhesus Monkey

Biology of reproduction, 2002-02, Vol.66 (2), p.486-494

2002

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Efficacy of lentivirus-mediated gene therapy in an Omenn syndrome recombination-activating gene 2 mouse model is not hindered by inflammation and immune dysregulation

Journal of allergy and clinical immunology, 2018-09, Vol.142 (3), p.928-941.e8

2018

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Hypothermic storage of hematopoetic stem cells can be used as an alternative to short-term cryopreservation

Experimental hematology, 2017-09, Vol.53, p.S136-S136

2017

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The Outcome of Local Radiation Injuries: 14 Years of Follow-up after the Chernobyl Accident

Radiation research, 2001-03, Vol.155 (3), p.409-416

2001

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Thrombopoietin promotes hematopoietic recovery and survival after high-dose whole body irradiation

International journal of radiation oncology, biology, physics, 1999-03, Vol.43 (4), p.867-875

1999

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Correction of Murine Rag2 Severe Combined Immunodeficiency by Lentiviral Gene Therapy Using a Codon-optimized RAG2 Therapeutic Transgene

Molecular therapy, 2012-10, Vol.20 (10), p.1968-1980

2012

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Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

The Journal of clinical investigation, 2007-08, Vol.117 (8), p.2225-2232

2007

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The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

Carcinogenesis (New York), 2015-06, Vol.36 Suppl 1 (Suppl 1), p.S38-S60

2015

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Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

The Journal of clinical investigation, 2007-08, Vol.117 (8), p.2241-2249

2007

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Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors

Experimental hematology, 2018-01, Vol.57, p.21-29

2018

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Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy

P1372: NON‐MYELOTOXIC CHEMICALS AS A PREPARATORY REGIMEN FOR HEMATOPOIETIC STEM CELL GENE THERAPY

Recombination-activating gene 1 ( Rag1 )–deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome

Lentiviral hematopoietic stem cell gene therapy in inherited metabolic disorders

Lentiviral Hematopoietic Stem Cell Gene Therapy Corrects Murine Pompe Disease

In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice

Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype

Anniversary issue on gene and cell therapy in the Netherlands

Mobilization of hepatic mesenchymal stem cells from human liver grafts

Correction of Murine SCID-X1 by Lentiviral Gene Therapy Using a Codon-optimized IL2RG Gene and Minimal Pretransplant Conditioning

Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE

5-Androstene-3β,17β-diol Promotes Recovery of Immature Hematopoietic Cells Following Myelosuppressive Radiation and Synergizes With Thrombopoietin

Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Immune and Lysoso- mal Enzyme Deficiencies

Chapter 6: Cell and cell system responses: Heterogeneity of radiation sensitivity of hemopoietic stem cell subsets

Human mesenchymal stem cells support B-cell and T-cell differentiation of cord blood CD34+ cells under optimized conditions

Long-Term Effects of Irradiation Before Adulthood on Reproductive Function in the Male Rhesus Monkey

Efficacy of lentivirus-mediated gene therapy in an Omenn syndrome recombination-activating gene 2 mouse model is not hindered by inflammation and immune dysregulation

Hypothermic storage of hematopoetic stem cells can be used as an alternative to short-term cryopreservation

The Outcome of Local Radiation Injuries: 14 Years of Follow-up after the Chernobyl Accident

Thrombopoietin promotes hematopoietic recovery and survival after high-dose whole body irradiation

Correction of Murine Rag2 Severe Combined Immunodeficiency by Lentiviral Gene Therapy Using a Codon-optimized RAG2 Therapeutic Transgene

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors

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