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Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease

Nature medicine, 2019-09, Vol.25 (9), p.1390-1395

2019

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Nucleosomes are well positioned in exons and carry characteristic histone modifications

Genome Research, 2009-10, Vol.19 (10), p.1732-1741

2009

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scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation

Scientific reports, 2022-04, Vol.12 (1), p.5772-5772, Article 5772

2022

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A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells

Lipids in health and disease, 2024-02, Vol.23 (1), p.48-48, Article 48

2024

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A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers

Human mutation, 2016-09, Vol.37 (9), p.904-913

2016

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Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Hepatology research, 2021-02, Vol.51 (2), p.233-238

2021

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Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Scientific reports, 2019-02, Vol.9 (1), p.2695-2695, Article 2695

2019

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Combinations of histone modifications mark exon inclusion levels

PloS one, 2012-01, Vol.7 (1), p.e29911-e29911

2012

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Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

EBioMedicine, 2019-02, Vol.40, p.595-604

2019

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rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

iScience, 2020-02, Vol.23 (2), p.100808-100808, Article 100808

2020

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ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

PLoS biology, 2009-12, Vol.7 (12), p.e1000256-e1000256

2009

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Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca²⁺ channels in retinal pigment epithelial cells

The FASEB journal, 2006-01, Vol.20 (1), p.178-180

2006

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Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment

Cancers, 2022-02, Vol.14 (4), p.1014

2022

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Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

Nucleic acids research, 2009-12, Vol.37 (22), p.7498-7508

2009

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Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

Genome Research, 2008-03, Vol.18 (3), p.380-392

2008

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Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

BMC cancer, 2011-10, Vol.11 (1), p.450-450, Article 450

2011

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Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

Genome Research, 2007-06, Vol.17 (6), p.708-719

2007

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Genetic prevention of hepatitis C virus‐induced liver fibrosis by allele‐specific downregulation of MERTK

Hepatology research, 2017-07, Vol.47 (8), p.826-830

2017

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Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

Human genomics, 2019-04, Vol.13 (1), p.20-20, Article 20

2019

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In vitro analysis of DNA-protein interactions by proximity ligation

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (9), p.3067-3072

2007

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Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation

iScience, 2019-10, Vol.20, p.42-59

2019

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Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

Biochimica et biophysica acta. Gene regulatory mechanisms, 2021-08, Vol.1864 (8), p.194724-194724, Article 194724

2021

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Identification of the gene responsible for Best macular dystrophy

Nature genetics, 1998-07, Vol.19 (3), p.241-247

1998

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ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

BMC medical genomics, 2013-11, Vol.6 (1), p.50-50, Article 50

2013

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Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

Human molecular genetics, 2005-11, Vol.14 (22), p.3435-3447

2005

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Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease

Nucleosomes are well positioned in exons and carry characteristic histone modifications

scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation

A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells

A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers

Single nucleus transcriptomics data integration recapitulates the major cell types in human liver

Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases

Combinations of histone modifications mark exon inclusion levels

Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival

rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca²⁺ channels in retinal pigment epithelial cells

Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment

Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

Genetic prevention of hepatitis C virus‐induced liver fibrosis by allele‐specific downregulation of MERTK

Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseases

In vitro analysis of DNA-protein interactions by proximity ligation

Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation

Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

Identification of the gene responsible for Best macular dystrophy

ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

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