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Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade

Journal of pharmaceutical analysis, 2022-02, Vol.12 (1), p.15-28

2022

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Medicinal Chemistry of Potassium Channel Modulators: An Update of Recent Progress (2011-2017)

Current medicinal chemistry, 2019-01, Vol.26 (12), p.2062-2084

2019

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Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents

European journal of medicinal chemistry, 2014-07, Vol.82, p.385-393

2014

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Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors

Bioorganic chemistry, 2021-05, Vol.110, p.104801-104801, Article 104801

2021

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Recent advances on patents of Plasmodium falciparum dihydroorotate dehydrogenase ( Pf DHODH) inhibitors as antimalarial agents

Expert opinion on therapeutic patents, 2023-09, Vol.33 (9), p.579-596

2023

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Biology and medicinal chemistry approaches towards various apoptosis inducers

Anti-cancer agents in medicinal chemistry, 2013-03, Vol.13 (3), p.433-455

2013

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CoMFA and CoMSIA studies on aryl carboxylic acid amide derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors

Current computer-aided drug design, 2012-12, Vol.8 (4), p.271-282

2012

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A Patent Review of Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors as Anticancer Agents and their Other Therapeutic Applications (1999-2022)

Recent patents on anti-cancer drug discovery, 2024-01, Vol.19 (3), p.280-297

2024

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Medicinal chemistry approaches for the discovery of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors as antimalarial agents

Future medicinal chemistry, 2023-07, Vol.15 (14), p.1295-1321

2023

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Histone deacetylase 2: A potential therapeutic target for cancer and neurodegenerative disorders

European journal of medicinal chemistry, 2021-04, Vol.216, p.113332-113332, Article 113332

2021

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Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives

Bioorganic chemistry, 2016-08, Vol.67, p.130-138

2016

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A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 2: Non-DSM compounds

Bioorganic chemistry, 2024-12, Vol.153, p.107754, Article 107754

2024

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Structure- and ligand-based drug design methods for the modeling of antimalarial agents: a review of updates from 2012 onwards

Journal of biomolecular structure & dynamics, 2022-01, Vol.40 (20), p.10481-10506

2022

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Integrated structure-guided computational design of novel substituted quinolizin-4-ones as Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors

Computational biology and chemistry, 2022-12, Vol.101, p.107787-107787, Article 107787

2022

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QSAR study on a series of aryl carboxylic acid amide derivatives as potential inhibitors of dihydroorotate dehydrogenase (DHODH)

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2013-03, Vol.9 (2), p.222-239

2013

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Hybrid Quantum Mechanics/Molecular Mechanics (QM/MM) Simulation: A Tool for Structure-Based Drug Design and Discovery

Mini reviews in medicinal chemistry, 2022-01, Vol.22 (8), p.1096-1107

2022

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Liquid phase combinatorial synthesis of 1,2,5-trisubstituted benzimidazole derivatives as human DHODH inhibitors

Bioorganic chemistry, 2017-12, Vol.75, p.118-126

2017

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Pharmacophore modeling, virtual screening, docking and in silico ADMET analysis of protein kinase B (PKB β) inhibitors

Journal of molecular graphics & modelling, 2013-05, Vol.42, p.17-25

2013

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Synthesis and QSAR modeling of novel benzimidazolo thiazolidinones, thiazinones and 5-arylidene-2-imino thiazolidinones as antibacterial agents

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2013-05, Vol.9 (3), p.474-485

2013

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Structure-guided discovery of adenosine triphosphate-competitive casein kinase 2 inhibitors

Future medicinal chemistry, 2023-06, Vol.15 (11), p.987-1014

2023

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In Silico Modeling for the Design of 2-substitted Benzimidazole Derivatives, and Prediction of Activity as Procaspase-3 Activators and Apoptosis Inducer

Letters in drug design & discovery, 2017-04, Vol.14 (4), p.387-397

2017

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A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds

Bioorganic chemistry, 2024-05, Vol.146, p.107249-107249, Article 107249

2024

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A Review on Forced Degradation Strategies to Establish the Stability of Therapeutic Peptide Formulations

International journal of peptide research and therapeutics, 2023-02, Vol.29 (2), p.22, Article 22

2023

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Ultrasound Assisted-synthesis and Biological Evaluation of Piperazinylprop- 1-en-2-yloxy-2H-chromen-2-ones as Cytotoxic Agents

Letters in drug design & discovery, 2017-01, Vol.14 (10)

2017

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CoMFA, CoMSIA, Topomer CoMFA, HQSAR, molecular docking and molecular dynamics simulations study of triazine morpholino derivatives as mTOR inhibitors for the treatment of breast cancer

Computational biology and chemistry, 2019-06, Vol.80, p.351-363

2019

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Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade

Medicinal Chemistry of Potassium Channel Modulators: An Update of Recent Progress (2011-2017)

Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents

Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors

Recent advances on patents of Plasmodium falciparum dihydroorotate dehydrogenase ( Pf DHODH) inhibitors as antimalarial agents

Biology and medicinal chemistry approaches towards various apoptosis inducers

CoMFA and CoMSIA studies on aryl carboxylic acid amide derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors

A Patent Review of Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors as Anticancer Agents and their Other Therapeutic Applications (1999-2022)

Medicinal chemistry approaches for the discovery of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors as antimalarial agents

Histone deacetylase 2: A potential therapeutic target for cancer and neurodegenerative disorders

Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives

A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 2: Non-DSM compounds

Structure- and ligand-based drug design methods for the modeling of antimalarial agents: a review of updates from 2012 onwards

Integrated structure-guided computational design of novel substituted quinolizin-4-ones as Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors

QSAR study on a series of aryl carboxylic acid amide derivatives as potential inhibitors of dihydroorotate dehydrogenase (DHODH)

Hybrid Quantum Mechanics/Molecular Mechanics (QM/MM) Simulation: A Tool for Structure-Based Drug Design and Discovery

Liquid phase combinatorial synthesis of 1,2,5-trisubstituted benzimidazole derivatives as human DHODH inhibitors

Pharmacophore modeling, virtual screening, docking and in silico ADMET analysis of protein kinase B (PKB β) inhibitors

Synthesis and QSAR modeling of novel benzimidazolo thiazolidinones, thiazinones and 5-arylidene-2-imino thiazolidinones as antibacterial agents

Structure-guided discovery of adenosine triphosphate-competitive casein kinase 2 inhibitors

In Silico Modeling for the Design of 2-substitted Benzimidazole Derivatives, and Prediction of Activity as Procaspase-3 Activators and Apoptosis Inducer

A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds

A Review on Forced Degradation Strategies to Establish the Stability of Therapeutic Peptide Formulations

Ultrasound Assisted-synthesis and Biological Evaluation of Piperazinylprop- 1-en-2-yloxy-2H-chromen-2-ones as Cytotoxic Agents

CoMFA, CoMSIA, Topomer CoMFA, HQSAR, molecular docking and molecular dynamics simulations study of triazine morpholino derivatives as mTOR inhibitors for the treatment of breast cancer

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