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Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands

Oncoimmunology, 2012-10, Vol.1 (7), p.1074-1083

2012

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Human B Cells Mediate Innate Anti-Cancer Cytotoxicity Through Concurrent Engagement of Multiple TNF Superfamily Ligands

Frontiers in immunology, 2022-03, Vol.13, p.837842

2022

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Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice

Cancer immunology research, 2016-05, Vol.4 (5), p.441-451

2016

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Dendritic-cell exosomes cross-present Toll-like receptor-ligands and activate bystander dendritic cells

Cellular immunology, 2014-05, Vol.289 (1-2), p.119-127

2014

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Constitutive Expression and Role of the TNF Family Ligands in Apoptotic Killing of Tumor Cells by Human NK Cells

The Journal of immunology (1950), 1999-11, Vol.163 (10), p.5358-5366

1999

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Essential role of the TNF-TNFR2 cognate interaction in mouse dendritic cell–natural killer cell crosstalk

Blood, 2007-04, Vol.109 (8), p.3333-3341

2007

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Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10

Oncoimmunology, 2012-07, Vol.1 (4), p.448-457

2012

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Soluble TNF Regulates TACE via AP-2α Transcription Factor in Mouse Dendritic Cells

The Journal of immunology (1950), 2017-01, Vol.198 (1), p.417-427

2017

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Sheddase Activity of Tumor Necrosis Factor-α Converting Enzyme Is Increased and Prognostically Valuable in Head and Neck Cancer

Cancer epidemiology, biomarkers & prevention, 2009-11, Vol.18 (11), p.2913-2922

2009

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Role of TNF superfamily ligands in innate immunity

Immunologic research, 2011-08, Vol.50 (2-3), p.159-174

Vujanovic, Nikola L.

2011

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Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1

British journal of cancer, 2000-02, Vol.82 (4), p.981-989

2000

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Innate Direct Anticancer Effector Function of Human Immature Dendritic Cells. I. Involvement of an Apoptosis-Inducing Pathway

The Journal of immunology (1950), 2002-02, Vol.168 (4), p.1823-1830

2002

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Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15

Blood, 2010-07, Vol.116 (4), p.575-583

2010

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Development of flow cytometry assays for measuring cell-membrane enzyme activity on individual cells

Journal of Cancer, 2020, Vol.11 (3), p.702-715

2020

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ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

Journal of Cancer, 2018-01, Vol.9 (14), p.2559-2570

2018

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Dendritic cells and natural killer cells interact via multiple TNF family molecules

Journal of leukocyte biology, 2005-03, Vol.77 (3), p.408-413

2005

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Suppression of natural killer-cell and dendritic-cell apoptotic tumoricidal activity in patients with head and neck cancer

Head & neck, 2013-03, Vol.35 (3), p.388-398

2013

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Role of TNF Family Ligands in Antitumor Activity of Natural Killer Cells

International reviews of immunology, 2001, Vol.20 (3-4), p.415-437

Vujanovic, Nikola L.

2001

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Innate Direct Anticancer Effector Function of Human Immature Dendritic Cells. II. Role of TNF, Lymphotoxin-α1β2, Fas Ligand, and TNF-Related Apoptosis-Inducing Ligand

The Journal of immunology (1950), 2002-02, Vol.168 (4), p.1831-1839

2002

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O1.2 Single cell RNA sequencing allows mapping of HPV transcripts in head and neck cancer epithelial cells

Oral oncology, 2022-11, Vol.134, p.106169, Article 106169

2022

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Cellular Immune and Genomic Biomarkers in NRG-HN003, a Phase I Study Adding Pembrolizumab to Adjuvant Cisplatin and Radiation Therapy (CRT) in Pathologically High-Risk Head and Neck Cancer (HNSCC)

International journal of radiation oncology, biology, physics, 2024-10, Vol.120 (2), p.S129-S130

2024

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NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer with Exploratory Biomarker Correlatives

International journal of radiation oncology, biology, physics, 2024-04, Vol.118 (5), p.e10-e11

2024

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A Phase II Trial of Personalized Immunotherapy in Patients (pts) with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M HNSCC) That Have Progressed on Prior Immunotherapy

International journal of radiation oncology, biology, physics, 2024-04, Vol.118 (5), p.e4-e4

2024

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856MO A randomized phase II study of concurrent vs. sequential pembrolizumab with chemoradiation (CRT) in locally advanced head and neck cancer (LA HNSCC): 4-year results and tumor-immune microenvironment analysis

Annals of oncology, 2023-10, Vol.34, p.S557-S558

2023

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IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro

Cancer gene therapy, 2006-08, Vol.13 (8), p.798-805

2006

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Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands

Human B Cells Mediate Innate Anti-Cancer Cytotoxicity Through Concurrent Engagement of Multiple TNF Superfamily Ligands

Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice

Dendritic-cell exosomes cross-present Toll-like receptor-ligands and activate bystander dendritic cells

Constitutive Expression and Role of the TNF Family Ligands in Apoptotic Killing of Tumor Cells by Human NK Cells

Essential role of the TNF-TNFR2 cognate interaction in mouse dendritic cell–natural killer cell crosstalk

Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10

Soluble TNF Regulates TACE via AP-2α Transcription Factor in Mouse Dendritic Cells

Sheddase Activity of Tumor Necrosis Factor-α Converting Enzyme Is Increased and Prognostically Valuable in Head and Neck Cancer

Role of TNF superfamily ligands in innate immunity

Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1

Innate Direct Anticancer Effector Function of Human Immature Dendritic Cells. I. Involvement of an Apoptosis-Inducing Pathway

Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15

Development of flow cytometry assays for measuring cell-membrane enzyme activity on individual cells

ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

Dendritic cells and natural killer cells interact via multiple TNF family molecules

Suppression of natural killer-cell and dendritic-cell apoptotic tumoricidal activity in patients with head and neck cancer

Role of TNF Family Ligands in Antitumor Activity of Natural Killer Cells

Innate Direct Anticancer Effector Function of Human Immature Dendritic Cells. II. Role of TNF, Lymphotoxin-α1β2, Fas Ligand, and TNF-Related Apoptosis-Inducing Ligand

O1.2 Single cell RNA sequencing allows mapping of HPV transcripts in head and neck cancer epithelial cells

Cellular Immune and Genomic Biomarkers in NRG-HN003, a Phase I Study Adding Pembrolizumab to Adjuvant Cisplatin and Radiation Therapy (CRT) in Pathologically High-Risk Head and Neck Cancer (HNSCC)

NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer with Exploratory Biomarker Correlatives

A Phase II Trial of Personalized Immunotherapy in Patients (pts) with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M HNSCC) That Have Progressed on Prior Immunotherapy

856MO A randomized phase II study of concurrent vs. sequential pembrolizumab with chemoradiation (CRT) in locally advanced head and neck cancer (LA HNSCC): 4-year results and tumor-immune microenvironment analysis

IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro

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