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Simultaneous flow cytometric immunophenotyping of necroptosis, apoptosis and RIP1-dependent apoptosis

Methods (San Diego, Calif.), 2018-02, Vol.134-135, p.56-66

2018

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Simultaneous polychromatic flow cytometric detection of multiple forms of regulated cell death

Apoptosis (London), 2019-06, Vol.24 (5-6), p.453-464

2019

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Association of innate immune activation with latent Epstein-Barr virus in active MS lesions

Neurology, 2012-01, Vol.78 (1), p.15-23

2012

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Translational Mini‐Review Series on B cell subsets in disease. Transitional B cells in systemic lupus erythematosus and Sjögren's syndrome: clinical implications and effects of B cell‐targeted therapies

Clinical and experimental immunology, 2012-01, Vol.167 (1), p.7-14

2012

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DOP18 OSM neutralisation in IBD mucosal explant cultures reduces pro-inflammatory cytokine production

Journal of Crohn's and colitis, 2019-01, Vol.13 (Supplement_1), p.S037-S037

2019

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Antigen presenting cells and T cell interactions in the gastrointestinal tract

Molecular nutrition & food research, 2009-10, Vol.53 (10), p.1352-1352

2009

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Antigen presenting cells and T cell interactions in the gastrointestinal tract

Molecular nutrition & food research, 2009-08, Vol.53 (8), p.947-951

2009

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Both IL‐12 and IL‐18 contribute to small intestinal Th1‐type immunopathology following oral infection with Toxoplasma gondii, but IL‐12 is dominant over IL‐18 in parasite control

European journal of immunology, 2004-11, Vol.34 (11), p.3197-3207

2004

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OC-009 Human anti-microbial v[delta]2+ t-cells are novel intestinal lymphocytes with functional relevance in crohn's disease

Gut, 2012-07, Vol.61, p.A4

2012

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OC-009 Human anti-microbial vδ2+ t-cells are novel intestinal lymphocytes with functional relevance in crohn's disease

Gut, 2012-07, Vol.61 (Suppl 2), p.A4-A4

2012

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P066 Human intestinal Vδ2+ T-cells promote mucosal inflammation in Crohn's disease and are selectively ablated by azathioprine therapy

Journal of Crohn's and colitis, 2013-02, Vol.7, p.S35-S36

2013

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OR3-001 – RIP2 kinase is activated in Blau Syndrome and IBD

Pediatric rheumatology online journal, 2013-11, Vol.11 (S1), p.A3-A3, Article A3

2013

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Flow Cytometry Reveals the Nature of Oncotic Cells

International journal of molecular sciences, 2019-09, Vol.20 (18), p.4379

2019

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Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3

Cell reports (Cambridge), 2019-06, Vol.27 (13), p.3956-3971.e6

2019

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Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Communications biology, 2020-03, Vol.3 (1), p.140, Article 140

2020

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Reduced CD27 - IgD - B Cells in Blood and Raised CD27 - IgD - B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease

Frontiers in immunology, 2019-03, Vol.10, p.361

2019

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Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Nature communications, 2018-09, Vol.9 (1), p.3857-15, Article 3857

2018

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Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease

Scientific reports, 2021-09, Vol.11 (1), p.19422-19422, Article 19422

2021

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Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

Scientific reports, 2018-03, Vol.8 (1), p.4941-13, Article 4941

2018

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Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients

Scientific reports, 2019-10, Vol.9 (1), p.14042-12, Article 14042

2019

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Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease

PloS one, 2019-04, Vol.14 (4), p.e0215033-e0215033

2019

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IgA-Producing Plasma Cells Originate From Germinal Centers That Are Induced by B-Cell Receptor Engagement in Humans

Gastroenterology (New York, N.Y. 1943), 2011-03, Vol.140 (3), p.947-956

2011

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Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation

Cell reports (Cambridge), 2019-04, Vol.27 (5), p.1461-1471.e4

2019

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A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis

Scientific reports, 2017-08, Vol.7 (1), p.10180, Article 10180

2017

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Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Journal of medicinal chemistry, 2017-02, Vol.60 (4), p.1247-1261

2017

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Simultaneous flow cytometric immunophenotyping of necroptosis, apoptosis and RIP1-dependent apoptosis

Simultaneous polychromatic flow cytometric detection of multiple forms of regulated cell death

Association of innate immune activation with latent Epstein-Barr virus in active MS lesions

Translational Mini‐Review Series on B cell subsets in disease. Transitional B cells in systemic lupus erythematosus and Sjögren's syndrome: clinical implications and effects of B cell‐targeted therapies

DOP18 OSM neutralisation in IBD mucosal explant cultures reduces pro-inflammatory cytokine production

Antigen presenting cells and T cell interactions in the gastrointestinal tract

Antigen presenting cells and T cell interactions in the gastrointestinal tract

Both IL‐12 and IL‐18 contribute to small intestinal Th1‐type immunopathology following oral infection with Toxoplasma gondii, but IL‐12 is dominant over IL‐18 in parasite control

OC-009 Human anti-microbial v[delta]2+ t-cells are novel intestinal lymphocytes with functional relevance in crohn's disease

OC-009 Human anti-microbial vδ2+ t-cells are novel intestinal lymphocytes with functional relevance in crohn's disease

P066 Human intestinal Vδ2+ T-cells promote mucosal inflammation in Crohn's disease and are selectively ablated by azathioprine therapy

OR3-001 – RIP2 kinase is activated in Blau Syndrome and IBD

Flow Cytometry Reveals the Nature of Oncotic Cells

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Reduced CD27 - IgD - B Cells in Blood and Raised CD27 - IgD - B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients

Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease

IgA-Producing Plasma Cells Originate From Germinal Centers That Are Induced by B-Cell Receptor Engagement in Humans

Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation

A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

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