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Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.4573-4589

2015

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Effects of focal plane parameters on extended shortwave infrared imaging system performance

Optical engineering, 2024-09, Vol.63 (9)

2024

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Minimum significant ratio of selectivity ratios (MSRSR) and confidence in ratio of selectivity ratios (CRSR): quantitative measures for selectivity ratios obtained by screening assays

Journal of biomolecular screening, 2012-08, Vol.17 (7), p.857-867

2012

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The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions

Cell, 1990-06, Vol.61 (6), p.1021-1033

1990

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Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (20), p.4399-4404

2015

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Design and synthesis of tricyclic cores for kinase inhibition

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.693-698

2013

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Anterior pituitary development: Short tales from dwarf mice

Cell, 1992-08, Vol.70 (4), p.527-530

1992

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Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor

BMC structural biology, 2012-09, Vol.12 (1), p.22-22

2012

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Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors

Genes & development, 1990-05, Vol.4 (5), p.695-711

1990

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POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter

Genes & development, 1991-07, Vol.5 (7), p.1309-1320

1991

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Immunohistochemical expression of Pit-1 protein in human pituitary adenomas

Endocrine pathology, 1993-12, Vol.4 (4), p.201-204

1993

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cis-Element clustering correlates with dose-dependent pro- and antisignaling effects of IL18

Genes and immunity, 2004-07, Vol.5 (5), p.354-362

2004

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An alternative Pit-1 RNA splicing product reveals modular binding and nonmodular transcriptional activities of the POU-specific domain

Molecular endocrinology (Baltimore, Md.), 1993-12, Vol.7 (12), p.1551-1560

1993

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Alternative translation initiation site usage results in two structurally distinct forms of Pit-1

The Journal of biological chemistry, 1991-07, Vol.266 (20), p.12832-12835

1991

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Structure and promoter activity of the mouse CDC25A gene

Mammalian genome, 2000-12, Vol.11 (12), p.1063-1069

2000

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Immunoglobulin gene ‘remnant’ DNA - implications for antibody gene recombination

Nucleic acids research, 1984-05, Vol.12 (10), p.4229-4246

1984

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AN ANALYSIS OF THE GENES AND DNA SEQUENCES ENCODED IN THE SHORT COMPONENT TERMINAL REPEAT OF HERPES SIMPLEX VIRUS-1

HUBENTHAL-VOSS, JEFFREY W

1988

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Targeting Metabolism to Improve the Tumor Microenvironment for Cancer Immunotherapy

Molecular cell, 2020-06, Vol.78 (6), p.1019-1033

2020

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Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease

The New England journal of medicine, 2019-04, Vol.380 (15), p.1408-1420

2019

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Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease

The New England journal of medicine, 2018-05, Vol.378 (18), p.1691-1703

2018

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A Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor

The New England journal of medicine, 2013-08, Vol.369 (7), p.640-648

2013

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Surface energy balance of sub‐Arctic roads with varying snow regimes and properties in permafrost regions

Permafrost and periglacial processes, 2021-10, Vol.32 (4), p.681-701

2021

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Influence of vertical and lateral heat transfer on permafrost thaw, peatland landscape transition, and groundwater flow

Water resources research, 2016-02, Vol.52 (2), p.1286-1305

2016

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The Occurrence of Rocky Habitable-zone Planets around Solar-like Stars from Kepler Data

The Astronomical journal, 2021-01, Vol.161 (1), p.36

2021

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Exercise training increases size of hippocampus and improves memory

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (7), p.3017-3022

2011

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Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

Effects of focal plane parameters on extended shortwave infrared imaging system performance

Minimum significant ratio of selectivity ratios (MSRSR) and confidence in ratio of selectivity ratios (CRSR): quantitative measures for selectivity ratios obtained by screening assays

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions

Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors

Design and synthesis of tricyclic cores for kinase inhibition

Anterior pituitary development: Short tales from dwarf mice

Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor

Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors

POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter

Immunohistochemical expression of Pit-1 protein in human pituitary adenomas

cis-Element clustering correlates with dose-dependent pro- and antisignaling effects of IL18

An alternative Pit-1 RNA splicing product reveals modular binding and nonmodular transcriptional activities of the POU-specific domain

Alternative translation initiation site usage results in two structurally distinct forms of Pit-1

Structure and promoter activity of the mouse CDC25A gene

Immunoglobulin gene ‘remnant’ DNA - implications for antibody gene recombination

AN ANALYSIS OF THE GENES AND DNA SEQUENCES ENCODED IN THE SHORT COMPONENT TERMINAL REPEAT OF HERPES SIMPLEX VIRUS-1

Targeting Metabolism to Improve the Tumor Microenvironment for Cancer Immunotherapy

Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease

Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease

A Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor

Surface energy balance of sub‐Arctic roads with varying snow regimes and properties in permafrost regions

Influence of vertical and lateral heat transfer on permafrost thaw, peatland landscape transition, and groundwater flow

The Occurrence of Rocky Habitable-zone Planets around Solar-like Stars from Kepler Data

Exercise training increases size of hippocampus and improves memory

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