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Sustained intestinal epithelial monolayer wound closure after transient application of a FAK-activating small molecule

PloS one, 2024-08, Vol.19 (8), p.e0304010

2024

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Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation

Cellular physiology and biochemistry, 2018-01, Vol.48 (3), p.1274-1290

2018

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ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain

Pharmacology research & perspectives, 2021-04, Vol.9 (2), p.e00737-n/a

2021

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A murine model of Lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system

PLoS pathogens, 2021-02, Vol.17 (2), p.e1009256-e1009256

2021

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Vil-Cre specific Schlafen 3 knockout mice exhibit sex-specific differences in intestinal differentiation markers and Schlafen family members expression levels

PloS one, 2021-10, Vol.16 (10), p.e0259195-e0259195

2021

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Schlafen 3 knockout mice display gender-specific differences in weight gain, food efficiency, and expression of markers of intestinal epithelial differentiation, metabolism, and immune cell function

PloS one, 2019-07, Vol.14 (7), p.e0219267-e0219267

2019

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Schlafens: Emerging Proteins in Cancer Cell Biology

Cells (Basel, Switzerland), 2021-08, Vol.10 (9), p.2238

2021

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Focal Adhesion Kinase and Colony Stimulating Factors: Intestinal Homeostasis and Innate Immunity Crosstalk

Cells (Basel, Switzerland), 2024-07, Vol.13 (14), p.1178

2024

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Current Immunotherapy Treatments of Primary Breast Cancer Subtypes

Biomedicines, 2024-04, Vol.12 (4), p.895

2024

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Microbiome diversity declines while distinct expansions of Th17, iNKT, and dendritic cell subpopulations emerge after anastomosis surgery

Gut pathogens, 2021-08, Vol.13 (1), p.51-51, Article 51

2021

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Schlafen Family Intra-Regulation by IFN-α2 in Triple-Negative Breast Cancer

Cancers, 2023-11, Vol.15 (23), p.5658

2023

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Cognate interaction with iNKT cells expands IL-10–producing B regulatory cells

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12474-12479

2015

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Loss of Schlafen3 influences the expression levels of Schlafen family members in ileum, thymus, and spleen tissue

PeerJ (San Francisco, CA), 2020-01, Vol.8, p.e8461-e8461, Article e8461

2020

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Schlafen 12 Slows TNBC Tumor Growth, Induces Luminal Markers, and Predicts Favorable Survival

Cancers, 2023-01, Vol.15 (2), p.402

2023

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Vil-Cre specific Slfn3KO mice exhibit sex-specific differences in lung, stomach, cecum, kidney, and proximal colon differentiation markers and Slfn family members expression levels

Biochemistry and biophysics reports, 2023-12, Vol.36, p.101552-101552, Article 101552

2023

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Schlafen 12 Is Prognostically Favorable and Reduces C-Myc and Proliferation in Lung Adenocarcinoma but Not in Lung Squamous Cell Carcinoma

Cancers, 2020-10, Vol.12 (10), p.2738

2020

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The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism

The Journal of nutritional biochemistry, 2012-10, Vol.23 (10), p.1201-1206

2012

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Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells

Human cell : official journal of Human Cell Research Society, 2019-07, Vol.32 (3), p.240-250

2019

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A novel drug-like water-soluble small molecule Focal Adhesion Kinase (FAK) activator promotes intestinal mucosal healing

Current research in pharmacology and drug discovery, 2023-01, Vol.4, p.100147, Article 100147

2023

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RNA Sequencing of Intestinal Enterocytes Pre- and Post-Roux-en-Y Gastric Bypass Reveals Alteration in Gene Expression Related to Enterocyte Differentiation, Restitution, and Obesity with Regulation by Schlafen 12

Cells (Basel, Switzerland), 2022-10, Vol.11 (20), p.3283

2022

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Small molecule FAK activator promotes human intestinal epithelial monolayer wound closure and mouse ulcer healing

Scientific reports, 2019-10, Vol.9 (1), p.14669-11, Article 14669

2019

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Invariant NKT cells provide innate and adaptive help for B cells

Current opinion in immunology, 2014-06, Vol.28, p.12-17

2014

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Glutathionyl systems and metabolic dysfunction in obesity

Nutrition reviews, 2015-12, Vol.73 (12), p.858-868

2015

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Gene expression profiling and network analysis of peripheral blood monocytes in a chronic model of allergic asthma

Microbiology and immunology, 2010-09, Vol.54 (9), p.558-563

2010

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Loss of Slfn3 induces a sex-dependent repair vulnerability after 50% bowel resection

American journal of physiology: Gastrointestinal and liver physiology, 2021-02, Vol.320 (2), p.G136-G152

2021

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Sustained intestinal epithelial monolayer wound closure after transient application of a FAK-activating small molecule

Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation

ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain

A murine model of Lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system

Vil-Cre specific Schlafen 3 knockout mice exhibit sex-specific differences in intestinal differentiation markers and Schlafen family members expression levels

Schlafen 3 knockout mice display gender-specific differences in weight gain, food efficiency, and expression of markers of intestinal epithelial differentiation, metabolism, and immune cell function

Schlafens: Emerging Proteins in Cancer Cell Biology

Focal Adhesion Kinase and Colony Stimulating Factors: Intestinal Homeostasis and Innate Immunity Crosstalk

Current Immunotherapy Treatments of Primary Breast Cancer Subtypes

Microbiome diversity declines while distinct expansions of Th17, iNKT, and dendritic cell subpopulations emerge after anastomosis surgery

Schlafen Family Intra-Regulation by IFN-α2 in Triple-Negative Breast Cancer

Cognate interaction with iNKT cells expands IL-10–producing B regulatory cells

Loss of Schlafen3 influences the expression levels of Schlafen family members in ileum, thymus, and spleen tissue

Schlafen 12 Slows TNBC Tumor Growth, Induces Luminal Markers, and Predicts Favorable Survival

Vil-Cre specific Slfn3KO mice exhibit sex-specific differences in lung, stomach, cecum, kidney, and proximal colon differentiation markers and Slfn family members expression levels

Schlafen 12 Is Prognostically Favorable and Reduces C-Myc and Proliferation in Lung Adenocarcinoma but Not in Lung Squamous Cell Carcinoma

The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism

Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells

A novel drug-like water-soluble small molecule Focal Adhesion Kinase (FAK) activator promotes intestinal mucosal healing

RNA Sequencing of Intestinal Enterocytes Pre- and Post-Roux-en-Y Gastric Bypass Reveals Alteration in Gene Expression Related to Enterocyte Differentiation, Restitution, and Obesity with Regulation by Schlafen 12

Small molecule FAK activator promotes human intestinal epithelial monolayer wound closure and mouse ulcer healing

Invariant NKT cells provide innate and adaptive help for B cells

Glutathionyl systems and metabolic dysfunction in obesity

Gene expression profiling and network analysis of peripheral blood monocytes in a chronic model of allergic asthma

Loss of Slfn3 induces a sex-dependent repair vulnerability after 50% bowel resection

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