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The Mechanisms and Therapeutic Potential of SGLT2 Inhibitors in Diabetes Mellitus

Annual review of medicine, 2015-01, Vol.66 (1), p.255-270

Vallon, Volker

2015

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Glucose transporters in the kidney in health and disease

Pflügers Archiv, 2020-09, Vol.472 (9), p.1345-1370

Vallon, Volker

2020

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The proximal tubule in the pathophysiology of the diabetic kidney

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-05, Vol.300 (5), p.R1009-R1022

Vallon, Volker

2011

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The tubular hypothesis of nephron filtration and diabetic kidney disease

Nature reviews. Nephrology, 2020-06, Vol.16 (6), p.317-336

2020

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Effects of SGLT2 Inhibitors on Kidney and Cardiovascular Function

Annual review of physiology, 2021-02, Vol.83 (1), p.503-528

2021

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SGLT2 inhibition and kidney protection

Clinical science (1979), 2018-06, Vol.132 (12), p.1329-1339

2018

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Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition

Diabetologia, 2017-02, Vol.60 (2), p.215-225

2017

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Effects of SGLT2 inhibitor and dietary NaCl on glomerular hemodynamics assessed by micropuncture in diabetic rats

American journal of physiology. Renal physiology, 2021-05, Vol.320 (5), p.F761-F771

2021

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Tubular Transport in Acute Kidney Injury: Relevance for Diagnosis, Prognosis and Intervention

Nephron (2015), 2016-01, Vol.134 (3), p.160-166

Vallon, Volker

2016

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The Potential Role of SGLT2 Inhibitors in the Treatment of Type 1 Diabetes Mellitus

Drugs (New York, N.Y.), 2018-05, Vol.78 (7), p.717-726

2018

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P2 receptors in the regulation of renal transport mechanisms

American journal of physiology. Renal physiology, 2008-01, Vol.294 (1), p.F10-F27

Vallon, Volker

2008

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Ketosis and diabetic ketoacidosis in response to SGLT2 inhibitors: Basic mechanisms and therapeutic perspectives

Diabetes/metabolism research and reviews, 2017-07, Vol.33 (5), p.n/a

2017

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Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney

Annual review of physiology, 2012-01, Vol.74 (1), p.351-375

2012

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Renal Effects of Sodium-Glucose Co-Transporter Inhibitors

The American journal of cardiology, 2019-12, Vol.124 (Suppl 1), p.S28-S35

2019

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Do Tubular Changes in the Diabetic Kidney Affect the Susceptibility to Acute Kidney Injury?

Nephron, 2014-01, Vol.127 (1-4), p.133-138

Vallon, Volker

2014

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Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2"

American Journal of Physiology: Cell Physiology, 2011-01, Vol.300 (1), p.C6-C8

Vallon, Volker

2011

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Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron

American journal of physiology. Renal physiology, 2016-06, Vol.310 (11), p.F1269-F1283

2016

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How Do Kidneys Adapt to a Deficit or Loss in Nephron Number?

Physiology (Bethesda, Md.), 2019-05, Vol.34 (3), p.189-197

2019

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A special issue on glucose transporters in health and disease

Pflügers Archiv, 2020-09, Vol.472 (9), p.1107-1109

2020

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Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

American journal of physiology. Renal physiology, 2015-06, Vol.308 (12), p.F1343-F1357

2015

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The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?

Kidney international, 2020-09, Vol.98 (3), p.579-589

2020

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Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences

Diabetes & vascular disease research, 2015-03, Vol.12 (2), p.78-89

2015

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A role for tubular Na + /H + exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin

American journal of physiology. Renal physiology, 2020-10, Vol.319 (4), p.F712-F728

2020

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A computational model for simulating solute transport and oxygen consumption along the nephrons

American journal of physiology. Renal physiology, 2016-12, Vol.311 (6), p.F1378-F1390

2016

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Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia

Journal of the American Society of Nephrology, 2019-04, Vol.30 (4), p.578-593

2019

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The Mechanisms and Therapeutic Potential of SGLT2 Inhibitors in Diabetes Mellitus

Glucose transporters in the kidney in health and disease

The proximal tubule in the pathophysiology of the diabetic kidney

The tubular hypothesis of nephron filtration and diabetic kidney disease

Effects of SGLT2 Inhibitors on Kidney and Cardiovascular Function

SGLT2 inhibition and kidney protection

Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition

Effects of SGLT2 inhibitor and dietary NaCl on glomerular hemodynamics assessed by micropuncture in diabetic rats

Tubular Transport in Acute Kidney Injury: Relevance for Diagnosis, Prognosis and Intervention

The Potential Role of SGLT2 Inhibitors in the Treatment of Type 1 Diabetes Mellitus

P2 receptors in the regulation of renal transport mechanisms

Ketosis and diabetic ketoacidosis in response to SGLT2 inhibitors: Basic mechanisms and therapeutic perspectives

Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney

Renal Effects of Sodium-Glucose Co-Transporter Inhibitors

Do Tubular Changes in the Diabetic Kidney Affect the Susceptibility to Acute Kidney Injury?

Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2"

Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron

How Do Kidneys Adapt to a Deficit or Loss in Nephron Number?

A special issue on glucose transporters in health and disease

Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?

Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences

A role for tubular Na + /H + exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin

A computational model for simulating solute transport and oxygen consumption along the nephrons

Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia

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