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N-Methyl-D-aspartate receptor antagonist d-methadone produces rapid, mTORC1-dependent antidepressant effects

Neuropsychopharmacology (New York, N.Y.), 2019-12, Vol.44 (13), p.2230-2238

2019

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The N-Methyl-D-Aspartate Receptor Antagonist d-Methadone Acutely Improves Depressive-Like Behavior in the Forced Swim Test Performance of Rats

Experimental and clinical psychopharmacology, 2020-04, Vol.28 (2), p.196-201

2020

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Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

The Journal of clinical investigation, 2004-12, Vol.114 (11), p.1624-1634

2004

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Functional Alterations in Memory Networks in Early Alzheimer’s Disease

Neuromolecular medicine, 2010-03, Vol.12 (1), p.27-43

2010

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Amyloid β-Peptide Inhibition of the PKA/CREB Pathway and Long-Term Potentiation: Reversibility by Drugs That Enhance cAMP Signaling

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.13217-13221

2002

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Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cellular Models of Parkinson's Disease

The Journal of neuroscience, 2002-12, Vol.22 (24), p.10690-10698

2002

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In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects

Neuropharmacology, 2017-05, Vol.117, p.171-181

2017

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REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial

The American journal of psychiatry, 2022-02, Vol.179 (2), p.122-131

2022

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"When Will All of This End?": A 65-Year-Old Man With Amyotrophic Lateral Sclerosis and Psychiatric Distress

The journal of clinical psychiatry, 2023-12, Vol.85 (1)

2023

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Ubiquitin Hydrolase Uch-L1 Rescues β-Amyloid-Induced Decreases in Synaptic Function and Contextual Memory

Cell, 2006-08, Vol.126 (4), p.775-788

2006

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Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

The Journal of clinical investigation, 2004-12, Vol.114 (11), p.1624-1634

2004

Volltextzugriff (PDF)

Biometric monitoring devices for assessing end points in clinical trials: developing an ecosystem

Nature reviews. Drug discovery, 2017-10, Vol.16 (10), p.736-736

2017

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Challenges, solutions, and recommendations for Alzheimer's disease combination therapy

Alzheimer's & dementia, 2016-05, Vol.12 (5), p.623-630

2016

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Identification of Diverse Nerve Growth Factor-Regulated Genes by Serial Analysis of Gene Expression (SAGE) Profiling

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (19), p.10424-10429

2000

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Efficacy and safety of a form of cranial electrical stimulation (CES) as an add-on intervention for treatment-resistant major depressive disorder: A three week double blind pilot study

Journal of psychiatric research, 2015-11, Vol.70, p.98-105

2015

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Amyloid β peptide adversely affects spine number and motility in hippocampal neurons

Molecular and cellular neuroscience, 2006-11, Vol.33 (3), p.274-282

2006

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A 12-week, randomized, double-blind, placebo-controlled, sequential parallel comparison trial of ziprasidone as monotherapy for major depressive disorder

The journal of clinical psychiatry, 2012-12, Vol.73 (12), p.1541

2012

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The effect of sildenafil on quality of life

Annals of clinical psychiatry, 2013-02, Vol.25 (1), p.3

2013

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Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols

Nucleic acids research, 2000-06, Vol.28 (12), p.E62

2000

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Endogenous APP derivatives oppositely modulate apoptosis through an autocrine loop

Neuroreport, 2000-05, Vol.11 (7), p.1375-1379

2000

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Dendrite and dendritic spine alterations in Alzheimer models

Journal of neurocytology, 2004-05, Vol.33 (3), p.377

2004

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Functional MRI Studies in Ageing and Early Alzheimer's Disease

Principles and Practice of Geriatric Psychiatry, 2010, p.437-445

2010

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Endogenous APP derivatives oppositely modulate apoptosis through an autocrine loop

Neuroreport, 2000-05, Vol.11 (7), p.1375-1379

2000

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Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J

Neurobiology of aging, 2009-02, Vol.30 (2), p.257-265

2009

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N-Methyl-D-aspartate receptor antagonist d-methadone produces rapid, mTORC1-dependent antidepressant effects

The N-Methyl-D-Aspartate Receptor Antagonist d-Methadone Acutely Improves Depressive-Like Behavior in the Forced Swim Test Performance of Rats

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

Functional Alterations in Memory Networks in Early Alzheimer’s Disease

Amyloid β-Peptide Inhibition of the PKA/CREB Pathway and Long-Term Potentiation: Reversibility by Drugs That Enhance cAMP Signaling

Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cellular Models of Parkinson's Disease

In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects

REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial

"When Will All of This End?": A 65-Year-Old Man With Amyotrophic Lateral Sclerosis and Psychiatric Distress

Ubiquitin Hydrolase Uch-L1 Rescues β-Amyloid-Induced Decreases in Synaptic Function and Contextual Memory

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

Biometric monitoring devices for assessing end points in clinical trials: developing an ecosystem

Challenges, solutions, and recommendations for Alzheimer's disease combination therapy

Identification of Diverse Nerve Growth Factor-Regulated Genes by Serial Analysis of Gene Expression (SAGE) Profiling

Efficacy and safety of a form of cranial electrical stimulation (CES) as an add-on intervention for treatment-resistant major depressive disorder: A three week double blind pilot study

Amyloid β peptide adversely affects spine number and motility in hippocampal neurons

A 12-week, randomized, double-blind, placebo-controlled, sequential parallel comparison trial of ziprasidone as monotherapy for major depressive disorder

The effect of sildenafil on quality of life

Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols

Endogenous APP derivatives oppositely modulate apoptosis through an autocrine loop

Dendrite and dendritic spine alterations in Alzheimer models

Functional MRI Studies in Ageing and Early Alzheimer's Disease

Endogenous APP derivatives oppositely modulate apoptosis through an autocrine loop

Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J

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