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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Nature reviews. Endocrinology, 2019-10, Vol.15 (10), p.569-589

2019

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Metformin: From Mechanisms of Action to Therapies

Cell metabolism, 2014-12, Vol.20 (6), p.953-966

2014

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Promise and challenges for direct small molecule AMPK activators

Biochemical pharmacology, 2018-07, Vol.153, p.147-158

2018

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Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism

Cell metabolism, 2015-06, Vol.21 (6), p.799-804

2015

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature cell biology, 2011-02, Vol.13 (2), p.132

2011

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Cellular and molecular mechanisms of metformin: an overview

Clinical science (1979), 2012-03, Vol.122 (6), p.253

2012

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AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2826

2018

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AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Annals of the rheumatic diseases, 2016-01, Vol.75 (1), p.286-294

2016

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Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

Diabetes (New York, N.Y.), 2016-01, Vol.65 (1), p.188-200

2016

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Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

The Journal of clinical investigation, 2010-07, Vol.120 (7), p.2355-2369

2010

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AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

Journal of leukocyte biology, 2013-12, Vol.94 (6), p.1113-1121

2013

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Targeting the AMPK pathway for the treatment of Type 2 diabetes

Frontiers in bioscience (Landmark. Print), 2009-01, Vol.14 (9), p.3380

2009

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AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5171

2019

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AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

Cell metabolism, 2013-08, Vol.18 (2), p.251-264

2013

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Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Circulation research, 2016-08, Vol.119 (5), p.652-665

2016

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AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

EBioMedicine, 2018-02, Vol.28 (C), p.194-209

2018

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AMP-Activated Protein Kinase Signalling

International journal of molecular sciences, 2019-02, Vol.20 (3), p.766

2019

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Nature communications, 2018-01, Vol.9 (1), p.374-17, Article 374

2018

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AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Cell metabolism, 2013-01, Vol.17 (1), p.113-124

2013

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AMP-Activated Protein Kinase and Metabolic Control

Diabetes - Perspectives in Drug Therapy, 2011-01, Vol.203 (203), p.303-330

Schwanstecher, Mathias

2011

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Diabetes (New York, N.Y.), 2017-03, Vol.66 (3), p.598-612

2017

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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.E8675-E8684

2017

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AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.554-563

2010

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Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

PLoS biology, 2015-12, Vol.13 (12), p.e1002309-e1002309

2015

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Metformin: From Mechanisms of Action to Therapies

Promise and challenges for direct small molecule AMPK activators

Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Cellular and molecular mechanisms of metformin: an overview

AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

Targeting the AMPK pathway for the treatment of Type 2 diabetes

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

AMP-Activated Protein Kinase Signalling

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

AMP-Activated Protein Kinase and Metabolic Control

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

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