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Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease

Nature communications, 2022-01, Vol.13 (1), p.159-19, Article 159

2022

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Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.1971-1976

2009

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Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

Acta neuropathologica, 2015-02, Vol.129 (2), p.183-206

2015

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Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Frontiers in neurology, 2019-11, Vol.10, p.1140-1140

2019

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Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (18), p.10417-10422

2003

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The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

Journal of Alzheimer's disease, 2018-01, Vol.64 (s1), p.S567-S610

2018

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The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease

Frontiers in neuroscience, 2022-01, Vol.15, p.768646-768646

2022

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An Essential Role for Alzheimer's-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

International journal of molecular sciences, 2022-02, Vol.23 (4), p.2208

2022

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Diet‐induced Alzheimer's‐like syndrome in the rabbit

Alzheimer's & dementia : translational research & clinical interventions, 2022, Vol.8 (1), p.e12241-n/a

2022

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Aβ oligomer induced cognitive impairment and evaluation of ACU193‐MNS‐based MRI in rabbit

Alzheimer's & dementia : translational research & clinical interventions, 2020, Vol.6 (1), p.e12087-n/a

2020

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Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease

Nature nanotechnology, 2015-01, Vol.10 (1), p.91-98

2015

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Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice

Psychopharmacology, 2023-12, Vol.240 (12), p.2641-2655

2023

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Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers

Molecular biology of the cell, 2017-10, Vol.28 (20), p.2623-2636

2017

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Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer’s patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability

Neuropathology and applied neurobiology, 2021-06, Vol.47 (4), p.488-505

2021

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Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease

Journal of proteome research, 2023-11, Vol.22 (11), p.3475-3488

2023

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Synaptic targeting by Alzheimer's-related amyloid beta oligomers

The Journal of neuroscience, 2004-11, Vol.24 (45), p.10191-10200

2004

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Monoclonal antibodies that target pathological assemblies of Aβ

Journal of neurochemistry, 2007, Vol.100 (1), p.23-35

2007

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Intrathecal amyloid‐beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease

Neuropathology and applied neurobiology, 2022-06, Vol.48 (4), p.e12800-n/a

2022

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A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid‐β oligomers

Journal of neurochemistry, 2017-09, Vol.142 (6), p.934-947

2017

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Self-Assembly of Aβ1 - 42 into Globular Neurotoxins

Biochemistry (Easton), 2003-11, Vol.42 (44), p.12749-12760

2003

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Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus

Brain research, 2002-01, Vol.924 (2), p.133-140

2002

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Brain transit and ameliorative effects of intranasally delivered anti-amyloid-β oligomer antibody in 5XFAD mice

Journal of Alzheimer's disease, 2013-01, Vol.35 (4), p.777-788

2013

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Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station

The Yale journal of biology & medicine, 2017-03, Vol.90 (1), p.45-61

2017

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Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies

Journal of neurochemistry, 2001-11, Vol.79 (3), p.595-605

2001

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Synapse-Binding Subpopulations of Aβ Oligomers Sensitive to Peptide Assembly Blockers and scFv Antibodies

ACS chemical neuroscience, 2012-11, Vol.3 (11), p.972-981

2012

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Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease

An Essential Role for Alzheimer's-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

Diet‐induced Alzheimer's‐like syndrome in the rabbit

Aβ oligomer induced cognitive impairment and evaluation of ACU193‐MNS‐based MRI in rabbit

Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease

Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice

Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers

Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer’s patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability

Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease

Synaptic targeting by Alzheimer's-related amyloid beta oligomers

Monoclonal antibodies that target pathological assemblies of Aβ

Intrathecal amyloid‐beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease

A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid‐β oligomers

Self-Assembly of Aβ1 - 42 into Globular Neurotoxins

Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus

Brain transit and ameliorative effects of intranasally delivered anti-amyloid-β oligomer antibody in 5XFAD mice

Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station

Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies

Synapse-Binding Subpopulations of Aβ Oligomers Sensitive to Peptide Assembly Blockers and scFv Antibodies

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