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Efficient Payload Delivery by a Bispecific Antibody-Drug Conjugate Targeting HER2 and CD63

Molecular cancer therapeutics, 2016-11, Vol.15 (11), p.2688-2697

2016

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Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors

The Journal of immunology (1950), 2011-02, Vol.186 (3), p.1840-1848

2011

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Crosstalk between human IgG isotypes and murine effector cells

The Journal of immunology (1950), 2012-10, Vol.189 (7), p.3430-3438

2012

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The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

Journal of Immunology, 2006-07, Vol.177 (1), p.362-371

2006

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Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Science (American Association for the Advancement of Science), 2007-09, Vol.317 (5844), p.1554-1557

2007

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Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

Blood, 2008-09, Vol.112 (6), p.2390-2399

2008

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Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG

mAbs, 2013-03, Vol.5 (2), p.219-228

2013

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Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys

Scientific reports, 2017-04, Vol.7 (1), p.992-11, Article 992

2017

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N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG

Biotechnology progress, 2009-01, Vol.25 (1), p.244-251

2009

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A simple, robust and highly efficient transient expression system for producing antibodies

Methods (San Diego, Calif.), 2014-01, Vol.65 (1), p.5-10

2014

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Daratumumab, a Novel Potent Human Anti-CD38 Monoclonal Antibody, Induces Significant Killing of Human Multiple Myeloma Cells: Therapeutic Implication

Blood, 2009-11, Vol.114 (22), p.608-608

2009

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Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells

The Journal of immunology (1950), 2016-12, Vol.197 (12), p.4829-4837

2016

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Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength

The Journal of immunology (1950), 2011-09, Vol.187 (6), p.3238-3246

2011

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The 33-kDa platelet alpha-granule membrane protein (GMP-33) is an N-terminal proteolytic fragment of thrombospondin

Thrombosis and haemostasis, 2001-09, Vol.86 (3), p.887-893

2001

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Binding of von Willebrand factor to collagen type III: role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains

Thrombosis and haemostasis, 2000-12, Vol.84 (6), p.1005-1011

2000

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Epidermal growth factor receptor (EGFR) antibody-induced antibody-dependent cellular cytotoxicity plays a prominent role in inhibiting tumorigenesis, even of tumor cells insensitive to EGFR signaling inhibition

The Journal of immunology (1950), 2011-09, Vol.187 (6), p.3383-3390

2011

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HER2 monoclonal antibodies that do not interfere with receptor heterodimerization-mediated signaling induce effective internalization and represent valuable components for rational antibody-drug conjugate design

mAbs, 2014-03, Vol.6 (2), p.392-402

2014

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Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease

Thrombosis and haemostasis, 1999-06, Vol.81 (6), p.976-983

1999

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Rapid production of recombinant human IgG With improved ADCC effector function in a transient expression system

Biotechnology and bioengineering, 2010-02, Vol.105 (2), p.350-357

2010

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Type I CD20 antibodies take over the B-cell receptor for complement-dependent cytotoxicity (CDC) of malignant B cells

Immunobiology (1979), 2012-11, Vol.217 (11), p.1218-1218

2012

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Melanocortin System and Eating Disorders

Annals of the New York Academy of Sciences, 2003-06, Vol.994 (1), p.267-274

2003

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Complement activation impacts B-cell depletion by both type I and type II CD20 monoclonal antibodies

Blood, 2008-11, Vol.112 (10), p.4354-4355

2008

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Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction

Arteriosclerosis, thrombosis, and vascular biology, 2000-06, Vol.20 (6), p.1661-1667

2000

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A3 domain is essential for interaction of von Willebrand factor with collagen type III

Thrombosis and haemostasis, 1996-06, Vol.75 (6), p.950-958

1996

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Acquired von Willebrand disease caused by an autoantibody selectively inhibiting the binding of von Willebrand factor to collagen

Blood, 1994-11, Vol.84 (10), p.3378-3384

1994

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Efficient Payload Delivery by a Bispecific Antibody-Drug Conjugate Targeting HER2 and CD63

Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors

Crosstalk between human IgG isotypes and murine effector cells

The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG

Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys

N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG

A simple, robust and highly efficient transient expression system for producing antibodies

Daratumumab, a Novel Potent Human Anti-CD38 Monoclonal Antibody, Induces Significant Killing of Human Multiple Myeloma Cells: Therapeutic Implication

Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells

Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength

The 33-kDa platelet alpha-granule membrane protein (GMP-33) is an N-terminal proteolytic fragment of thrombospondin

Binding of von Willebrand factor to collagen type III: role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains

Epidermal growth factor receptor (EGFR) antibody-induced antibody-dependent cellular cytotoxicity plays a prominent role in inhibiting tumorigenesis, even of tumor cells insensitive to EGFR signaling inhibition

HER2 monoclonal antibodies that do not interfere with receptor heterodimerization-mediated signaling induce effective internalization and represent valuable components for rational antibody-drug conjugate design

Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease

Rapid production of recombinant human IgG With improved ADCC effector function in a transient expression system

Type I CD20 antibodies take over the B-cell receptor for complement-dependent cytotoxicity (CDC) of malignant B cells

Melanocortin System and Eating Disorders

Complement activation impacts B-cell depletion by both type I and type II CD20 monoclonal antibodies

Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction

A3 domain is essential for interaction of von Willebrand factor with collagen type III

Acquired von Willebrand disease caused by an autoantibody selectively inhibiting the binding of von Willebrand factor to collagen

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