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4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy

BMB Reports, 2014, 47(3), , pp.122-129

2014

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Therapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies

Expert opinion on therapeutic targets, 2016-03, Vol.20 (3), p.361-373

2016

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Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003341-e1003341

2013

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Immunotherapy of cancer with 4-1BB

Molecular cancer therapeutics, 2012-05, Vol.11 (5), p.1062-1070

2012

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Exposure of a distinct PDCA-1+ (CD317) B cell population to agonistic anti-4-1BB (CD137) inhibits T and B cell responses both in vitro and in vivo

PloS one, 2012-11, Vol.7 (11), p.e50272

2012

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4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

Journal of leukocyte biology, 2004-05, Vol.75 (5), p.785-791

2004

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Immune Responses in 4-1BB (CD137)-Deficient Mice

The Journal of immunology (1950), 2002-06, Vol.168 (11), p.5483-5490

2002

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PDCA Expression by B Lymphocytes Reveals Important Functional Attributes

The Journal of immunology (1950), 2010-01, Vol.184 (2), p.807-815

2010

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CD137-Deficient Mice Have Reduced NK/NKT Cell Numbers and Function, Are Resistant to Lipopolysaccharide-Induced Shock Syndromes, and Have Lower IL-4 Responses

The Journal of immunology (1950), 2004-09, Vol.173 (6), p.4218-4229

2004

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4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms

Cytokine (Philadelphia, Pa.), 2006-06, Vol.34 (5), p.233-242

2006

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4-1BB signaling beyond T cells

Cellular & molecular immunology, 2011-07, Vol.8 (4), p.281-284

2011

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Harnessing immune checkpoints for cancer therapy

Immunotherapy, 2018-10, Vol.10 (14), p.1265-1284

2018

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Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis

Cytokine (Philadelphia, Pa.), 2012-03, Vol.57 (3), p.305-312

2012

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4-1BB-mediated immunotherapy of rheumatoid arthritis

Nature medicine, 2004-10, Vol.10 (10), p.1088-1094

2004

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Immunotherapy targeting 4-1BB and its ligand

International journal of hematology, 2006-01, Vol.83 (1), p.23-28

2006

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CD11c +CD8 + T cells: Two-faced adaptive immune regulators

Cellular immunology, 2010, Vol.264 (1), p.18-22

2010

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Dual immunoregulatory pathways of 4-1BB signaling

Journal of molecular medicine (Berlin, Germany), 2006-09, Vol.84 (9), p.726-736

2006

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4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells

The Journal of immunology (1950), 2011-08, Vol.187 (3), p.1120-1128

2011

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Origins and functional basis of regulatory CD11c⁺CD8⁺ T cells

European journal of immunology, 2009-06, Vol.39 (6), p.1552-1563

2009

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4–1BB signal stimulates the activation, expansion, and effector functions of γδ T cells in mice and humans

European journal of immunology, 2013-07, Vol.43 (7), p.1839-1848

2013

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In vivo 4-1BB deficiency in myeloid cells enhances peripheral T cell proliferation by increasing IL-15

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1580-1590

2015

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Peripheral 4-1BB signaling negatively regulates NK cell development through IFN-gamma

The Journal of immunology (1950), 2010-08, Vol.185 (3), p.1404-1411

2010

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TNF superfamily: Costimulation and clinical applications

Cell biology international, 2009-04, Vol.33 (4), p.453-465

2009

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Amelioration of Mercury-Induced Autoimmunity by 4-1BB

Journal of Immunology, 2006-10, Vol.177 (8), p.5708-5717

2006

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4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy

Therapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies

Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy

Immunotherapy of cancer with 4-1BB

Exposure of a distinct PDCA-1+ (CD317) B cell population to agonistic anti-4-1BB (CD137) inhibits T and B cell responses both in vitro and in vivo

4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

Immune evasion in cancer: Mechanistic basis and therapeutic strategies

Immune Responses in 4-1BB (CD137)-Deficient Mice

PDCA Expression by B Lymphocytes Reveals Important Functional Attributes

CD137-Deficient Mice Have Reduced NK/NKT Cell Numbers and Function, Are Resistant to Lipopolysaccharide-Induced Shock Syndromes, and Have Lower IL-4 Responses

4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms

4-1BB signaling beyond T cells

Harnessing immune checkpoints for cancer therapy

Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis

4-1BB-mediated immunotherapy of rheumatoid arthritis

Immunotherapy targeting 4-1BB and its ligand

CD11c +CD8 + T cells: Two-faced adaptive immune regulators

Dual immunoregulatory pathways of 4-1BB signaling

4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells

Origins and functional basis of regulatory CD11c⁺CD8⁺ T cells

4–1BB signal stimulates the activation, expansion, and effector functions of γδ T cells in mice and humans

In vivo 4-1BB deficiency in myeloid cells enhances peripheral T cell proliferation by increasing IL-15

Peripheral 4-1BB signaling negatively regulates NK cell development through IFN-gamma

TNF superfamily: Costimulation and clinical applications

Amelioration of Mercury-Induced Autoimmunity by 4-1BB

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