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The Tangle or Nuclear Receptors that Controls Xenobiotic Metabolism and Transport : Crosstalk and Consequences

Annual review of pharmacology and toxicology, 2008-01, Vol.48 (1), p.1-32

2008

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Colchicine Down-Regulates Cytochrome P450 2B6, 2C8, 2C9, and 3A4 in Human Hepatocytes by Affecting Their Glucocorticoid Receptor-Mediated Regulation

Molecular pharmacology, 2003-07, Vol.64 (1), p.160-169

2003

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Xenoreceptors CAR and PXR Activation and Consequences on Lipid Metabolism, Glucose Homeostasis, and Inflammatory Response

Molecular pharmaceutics, 2008-01, Vol.5 (1), p.35-41

2008

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A novel pregnane X receptor and S14‐mediated lipogenic pathway in human hepatocyte

Hepatology (Baltimore, Md.), 2009-06, Vol.49 (6), p.2068-2079

2009

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Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.209-217

2002

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Hepatic Expression of Thyroid Hormone-Responsive Spot 14 Protein Is Regulated by Constitutive Androstane Receptor (NR1I3)

Endocrinology (Philadelphia), 2010-04, Vol.151 (4), p.1653-1661

2010

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Ketoconazole and Miconazole Are Antagonists of the Human Glucocorticoid Receptor: Consequences on the Expression and Function of the Constitutive Androstane Receptor and the Pregnane X Receptor

Molecular pharmacology, 2006-07, Vol.70 (1), p.329-339

2006

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Interleukin 1β inhibits CAR‐induced expression of hepatic genes involved in drug and bilirubin clearance

Hepatology (Baltimore, Md.), 2004-10, Vol.40 (4), p.951-960

2004

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Dexamethasone Enhances Constitutive Androstane Receptor Expression in Human Hepatocytes: Consequences on Cytochrome P450 Gene Regulation

Molecular pharmacology, 2000-12, Vol.58 (6), p.1441-1450

2000

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The Small Heterodimer Partner Interacts with the Pregnane X Receptor and Represses Its Transcriptional Activity

Molecular endocrinology (Baltimore, Md.), 2003-09, Vol.17 (9), p.1693-1703

2003

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Transcriptional Analysis of the Orphan Nuclear Receptor Constitutive Androstane Receptor (NR1I3) Gene Promoter: Identification of a Distal Glucocorticoid Response Element

Molecular endocrinology (Baltimore, Md.), 2003-01, Vol.17 (1), p.42-55

2003

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Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes

Drug metabolism and disposition, 2001-10, Vol.29 (10), p.1325

2001

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Interleukin-6 Negatively Regulates the Expression of Pregnane X Receptor and Constitutively Activated Receptor in Primary Human Hepatocytes

Biochemical and biophysical research communications, 2000-08, Vol.274 (3), p.707-713

2000

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Constitutive androstane receptor–vitamin D receptor crosstalk: Consequence on CYP24 gene expression

Biochemical and biophysical research communications, 2007-08, Vol.360 (1), p.76-82

2007

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Identification of proteomic changes during human liver development by 2D-DIGE and mass spectrometry

Journal of hepatology, 2009-07, Vol.51 (1), p.114-126

2009

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Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes

The Journal of biological chemistry, 2002-07, Vol.277 (28), p.25125-25132

2002

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Possible involvement of pregnane X receptor–enhanced CYP24 expression in drug-induced osteomalacia

The Journal of clinical investigation, 2005-01, Vol.115 (1), p.177-186

2005

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Response to Zhou et al

The Journal of clinical investigation, 2006-10, Vol.116 (10), p.2564-2564

2006

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Cytoprotective properties of α-tocopherol are related to gene regulation in cultured d-galactosamine-treated human hepatocytes

Free radical biology & medicine, 2007-11, Vol.43 (10), p.1439-1452

2007

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Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line

Cellular signalling, 2005-02, Vol.17 (2), p.187-196

2005

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Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

Molecular pharmacology, 2000-08, Vol.58 (2), p.361-372

2000

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Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor

European journal of biochemistry, 2001-12, Vol.268 (24), p.6346-6358

2001

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Transcriptional Regulation of CYP2C9 Gene

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.209-217

2002

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Pathophysiological Factors Affecting CAR Gene Expression

Drug metabolism reviews, 2003-01, Vol.35 (4), p.255-268

2003

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Inflammation et métabolisme des médicaments: NF-κB et les xénorécepteurs CAR et PXR

M.S. Médecine sciences, 2008-03, Vol.24 (3), p.301-305

2008

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The Tangle or Nuclear Receptors that Controls Xenobiotic Metabolism and Transport : Crosstalk and Consequences

Colchicine Down-Regulates Cytochrome P450 2B6, 2C8, 2C9, and 3A4 in Human Hepatocytes by Affecting Their Glucocorticoid Receptor-Mediated Regulation

Xenoreceptors CAR and PXR Activation and Consequences on Lipid Metabolism, Glucose Homeostasis, and Inflammatory Response

A novel pregnane X receptor and S14‐mediated lipogenic pathway in human hepatocyte

Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor

Hepatic Expression of Thyroid Hormone-Responsive Spot 14 Protein Is Regulated by Constitutive Androstane Receptor (NR1I3)

Ketoconazole and Miconazole Are Antagonists of the Human Glucocorticoid Receptor: Consequences on the Expression and Function of the Constitutive Androstane Receptor and the Pregnane X Receptor

Interleukin 1β inhibits CAR‐induced expression of hepatic genes involved in drug and bilirubin clearance

Dexamethasone Enhances Constitutive Androstane Receptor Expression in Human Hepatocytes: Consequences on Cytochrome P450 Gene Regulation

The Small Heterodimer Partner Interacts with the Pregnane X Receptor and Represses Its Transcriptional Activity

Transcriptional Analysis of the Orphan Nuclear Receptor Constitutive Androstane Receptor (NR1I3) Gene Promoter: Identification of a Distal Glucocorticoid Response Element

Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes

Interleukin-6 Negatively Regulates the Expression of Pregnane X Receptor and Constitutively Activated Receptor in Primary Human Hepatocytes

Constitutive androstane receptor–vitamin D receptor crosstalk: Consequence on CYP24 gene expression

Identification of proteomic changes during human liver development by 2D-DIGE and mass spectrometry

Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes

Possible involvement of pregnane X receptor–enhanced CYP24 expression in drug-induced osteomalacia

Response to Zhou et al

Cytoprotective properties of α-tocopherol are related to gene regulation in cultured d-galactosamine-treated human hepatocytes

Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line

Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor

Transcriptional Regulation of CYP2C9 Gene

Pathophysiological Factors Affecting CAR Gene Expression

Inflammation et métabolisme des médicaments: NF-κB et les xénorécepteurs CAR et PXR

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