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In Vitro and In Vivo Metabolite Identification Studies for the New Synthetic Opioids Acetylfentanyl, Acrylfentanyl, Furanylfentanyl, and 4-Fluoro-Isobutyrylfentanyl

The AAPS journal, 2017-07, Vol.19 (4), p.1102-1122

2017

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Identification of AKB-48 and 5F-AKB-48 Metabolites in Authentic Human Urine Samples Using Human Liver Microsomes and Time of Flight Mass Spectrometry

Journal of analytical toxicology, 2015-07, Vol.39 (6), p.426-435

2015

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Characterization of recent non-fentanyl synthetic opioids via three different in vitro µ-opioid receptor activation assays

Archives of toxicology, 2022-03, Vol.96 (3), p.877-897

2022

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5F‐MDMB‐PICA metabolite identification and cannabinoid receptor activity

Drug testing and analysis, 2020-01, Vol.12 (1), p.127-135

2020

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Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis

Basic & clinical pharmacology & toxicology, 2023-03, Vol.132 (3), p.263-280

2023

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Correlations between metabolism and structural elements of the alicyclic fentanyl analogs cyclopropyl fentanyl, cyclobutyl fentanyl, cyclopentyl fentanyl, cyclohexyl fentanyl and 2,2,3,3-tetramethylcyclopropyl fentanyl studied by human hepatocytes and LC-QTOF-MS

Archives of toxicology, 2019-01, Vol.93 (1), p.95-106

2019

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Combination treatment with 6-mercaptopurine and allopurinol in HepG2 and HEK293 cells - Effects on gene expression levels and thiopurine metabolism

PloS one, 2017-03, Vol.12 (3), p.e0173825-e0173825

2017

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Erlotinib treatment induces cytochrome P450 3A activity in non‐small cell lung cancer patients

British journal of clinical pharmacology, 2019-08, Vol.85 (8), p.1704-1709

2019

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A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma

Journal of pharmaceutical and biomedical analysis, 2015-03, Vol.107, p.186-195

2015

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Metabolism of MMB022 and identification of dihydrodiol formation in vitro using synthesized standards

Drug testing and analysis, 2020-10, Vol.12 (10), p.1432-1441

2020

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LC-QTOF-MS Identification of Major Urinary Cyclopropylfentanyl Metabolites Using Synthesized Standards

Journal of analytical toxicology, 2019-09, Vol.43 (8), p.607-614

2019

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The influence of ABCG2 polymorphism on erlotinib efflux in the K562 cell line

Pharmacology research & perspectives, 2020-04, Vol.8 (2), p.e00581-n/a

2020

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Single-nucleotide polymorphisms of ABCG2 increase the efficacy of tyrosine kinase inhibitors in the K562 chronic myeloid leukemia cell line

Pharmacogenetics and genomics, 2014-01, Vol.24 (1), p.52-61

2014

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Metabolism of the benzodiazepines norflurazepam, flurazepam, fludiazepam and cinolazepam by human hepatocytes using high-resolution mass spectrometry and distinguishing their intake in authentic urine samples

Forensic toxicology, 2020, Vol.38 (1), p.79-94

2020

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Differences in cardiovascular toxicities associated with cigarette smoking and snuff use revealed using novel zebrafish models

Biology open, 2016-07, Vol.5 (7), p.970-978

2016

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Editorial Material: Putting Designer Drugs Back in Pandoras Box: Analytical Challenges and Metabolite Identification in CLINICAL CHEMISTRY, vol 62, issue 1, pp

Clinical chemistry (Baltimore, Md.), 2016, Vol.62 (1), p.4

2016

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In vitro characterization of new psychoactive substances at the μ-opioid, CB1, 5HT1A, and 5-HT2A receptors—On-target receptor potency and efficacy, and off-target effects

Forensic science international, 2020-12, Vol.317, p.110553, Article 110553

2020

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Femoral blood concentrations of flualprazolam in 33 postmortem cases

Forensic science international, 2020-02, Vol.307, p.110101, Article 110101

2020

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Biotransformation of the New Synthetic Cannabinoid with an Alkene, MDMB-4en-PINACA, by Human Hepatocytes, Human Liver Microsomes, and Human Urine and Blood

The AAPS journal, 2019-12, Vol.22 (1), p.13-13, Article 13

2019

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A reassessment of DNA-immunoprecipitation-based genomic profiling

Nature methods, 2018-07, Vol.15 (7), p.499

2018

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In vitro characterization of new psychoactive substances at the mu-opioid, CB1, 5HT(1A), and 5-HT2A receptors-On-target receptor potency and efficacy, and off-target effects

Forensic science international, 2020-12, Vol.317

2020

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Circumstances, Postmortem Findings, Blood Concentrations and Metabolism in a Series of Methoxyacetylfentanyl-Related Deaths

Journal of analytical toxicology, 2021-10, Vol.45 (8), p.760-771

2021

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Fatal Poisonings Associated with New Psychoactive Substances

New Psychoactive Substances, 2018-01, Vol.252, p.495-541

2018

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8-THC-COOH cross-reactivity with cannabinoid immunoassay kits and interference in chromatographic testing methods

Journal of analytical toxicology, 2023-09, Vol.47 (7), p.557-562

2023

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Using in vitro receptor activity studies of synthetic cannabinoids to support the risk assessment of new psychoactive substances – A Swedish strategy to protect public health from harm

Forensic science international, 2023-07, Vol.348, p.111691-111691, Article 111691

2023

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In Vitro and In Vivo Metabolite Identification Studies for the New Synthetic Opioids Acetylfentanyl, Acrylfentanyl, Furanylfentanyl, and 4-Fluoro-Isobutyrylfentanyl

Identification of AKB-48 and 5F-AKB-48 Metabolites in Authentic Human Urine Samples Using Human Liver Microsomes and Time of Flight Mass Spectrometry

Characterization of recent non-fentanyl synthetic opioids via three different in vitro µ-opioid receptor activation assays

5F‐MDMB‐PICA metabolite identification and cannabinoid receptor activity

Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis

Correlations between metabolism and structural elements of the alicyclic fentanyl analogs cyclopropyl fentanyl, cyclobutyl fentanyl, cyclopentyl fentanyl, cyclohexyl fentanyl and 2,2,3,3-tetramethylcyclopropyl fentanyl studied by human hepatocytes and LC-QTOF-MS

Combination treatment with 6-mercaptopurine and allopurinol in HepG2 and HEK293 cells - Effects on gene expression levels and thiopurine metabolism

Erlotinib treatment induces cytochrome P450 3A activity in non‐small cell lung cancer patients

A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma

Metabolism of MMB022 and identification of dihydrodiol formation in vitro using synthesized standards

LC-QTOF-MS Identification of Major Urinary Cyclopropylfentanyl Metabolites Using Synthesized Standards

The influence of ABCG2 polymorphism on erlotinib efflux in the K562 cell line

Single-nucleotide polymorphisms of ABCG2 increase the efficacy of tyrosine kinase inhibitors in the K562 chronic myeloid leukemia cell line

Metabolism of the benzodiazepines norflurazepam, flurazepam, fludiazepam and cinolazepam by human hepatocytes using high-resolution mass spectrometry and distinguishing their intake in authentic urine samples

Differences in cardiovascular toxicities associated with cigarette smoking and snuff use revealed using novel zebrafish models

Editorial Material: Putting Designer Drugs Back in Pandoras Box: Analytical Challenges and Metabolite Identification in CLINICAL CHEMISTRY, vol 62, issue 1, pp

In vitro characterization of new psychoactive substances at the μ-opioid, CB1, 5HT1A, and 5-HT2A receptors—On-target receptor potency and efficacy, and off-target effects

Femoral blood concentrations of flualprazolam in 33 postmortem cases

Biotransformation of the New Synthetic Cannabinoid with an Alkene, MDMB-4en-PINACA, by Human Hepatocytes, Human Liver Microsomes, and Human Urine and Blood

A reassessment of DNA-immunoprecipitation-based genomic profiling

In vitro characterization of new psychoactive substances at the mu-opioid, CB1, 5HT(1A), and 5-HT2A receptors-On-target receptor potency and efficacy, and off-target effects

Circumstances, Postmortem Findings, Blood Concentrations and Metabolism in a Series of Methoxyacetylfentanyl-Related Deaths

Fatal Poisonings Associated with New Psychoactive Substances

8-THC-COOH cross-reactivity with cannabinoid immunoassay kits and interference in chromatographic testing methods

Using in vitro receptor activity studies of synthetic cannabinoids to support the risk assessment of new psychoactive substances – A Swedish strategy to protect public health from harm

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