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CD25-targeted antibody-drug conjugate depletes regulatory T cells and eliminates established syngeneic tumors via antitumor immunity

Journal for immunotherapy of cancer, 2020-09, Vol.8 (2), p.e000860

2020

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TR1801‐ADC: a highly potent cMet antibody–drug conjugate with high activity in patient‐derived xenograft models of solid tumors

Molecular oncology, 2020-01, Vol.14 (1), p.54-68

2020

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Rationally Designed Short Polyisoprenol-Linked PglB Substrates for Engineered Polypeptide and Protein N‑Glycosylation

Journal of the American Chemical Society, 2014-01, Vol.136 (2), p.566-569

2014

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Chain-growth polyglycosylation: synthesis of linker-equipped mannosyl oligomers

Carbohydrate research, 2015-02, Vol.403, p.135-141

2015

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An antibacterial vaccination strategy based on a glycoconjugate containing the core lipopolysaccharide tetrasaccharide Hep2Kdo2

Nature chemistry, 2016-03, Vol.8 (3), p.242

2016

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Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

Chemical communications (Cambridge, England), 2010-12, Vol.46 (48), p.9119-9121

2010

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Thiyl Glycosylation of Olefinic Proteins: S-Linked Glycoconjugate Synthesis

Angewandte Chemie (International ed.), 2009-10, Vol.48 (42), p.7798-7802

2009

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Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography – high resolution mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2021-10, Vol.205, p.114287-114287, Article 114287

2021

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Comparison of Pyrrolobenzodiazepine Dimer Bis-imine versus Mono-imine: DNA Interstrand Cross-linking, Cytotoxicity, Antibody-Drug Conjugate Efficacy and Toxicity

Molecular cancer therapeutics, 2023-02, Vol.22 (2), p.254-263

2023

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Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody–Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer

Molecular cancer therapeutics, 2022-09, Vol.21 (9), p.1439-1448

2022

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Improved Physical Stability of an Antibody–Drug Conjugate Using Host–Guest Chemistry

Bioconjugate chemistry, 2020-01, Vol.31 (1), p.123-129

2020

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Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension

Bioconjugate chemistry, 2019-04, Vol.30 (4), p.1232-1243

2019

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Strategies in the Design and Use of Synthetic "Internal Glycan" Vaccines

Methods in enzymology, 2017, Vol.597, p.335-357

2017

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A Reactive Antibody Platform for One-Step Production of Antibody–Drug Conjugates through a Diels–Alder Reaction with Maleimide

Bioconjugate chemistry, 2019-09, Vol.30 (9), p.2340-2348

2019

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Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers

European journal of medicinal chemistry, 2019-10, Vol.179, p.591-607

2019

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Abstract 225: TR1801-ADC, an optimized anti cMet PBD ADC with high efficacy in solid tumors of the GI tract and head & neck cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.225-225

2019

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Abstract 5736: AZD9592: An EGFR-cMET bispecific antibody-drug conjugate (ADC) targeting key oncogenic drivers in non-small-cell lung cancer (NSCLC) and beyond

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5736-5736

2023

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MS of the six isomers of (GlcN)2(GlcNAc)2 aminoglucan tetrasaccharides (diacetylchitotetraoses): Rules of fragmentation for the sodiated molecules and application to sequence analysis of hetero-chitooligosaccharides

Carbohydrate polymers, 2011-03, Vol.84 (2), p.713-726

2011

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Comparison of pyrrolobenzodiazepine dimer bis-imine versus mono-imine: DNA interstrand cross-linking, cytotoxicity, and antibody-drug conjugate efficacy and toxicity

Molecular cancer therapeutics, 2022-12

2022

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Potent Fluoro-oligosaccharide Probes of Adhesion in Toxoplasmosis

Chembiochem : a European journal of chemical biology, 2009-10, Vol.10 (15), p.2522-2529

2009

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MS n of the six isomers of (GlcN) 2(GlcNAc) 2 aminoglucan tetrasaccharides (diacetylchitotetraoses): Rules of fragmentation for the sodiated molecules and application to sequence analysis of hetero-chitooligosaccharides

Carbohydrate polymers, 2011, Vol.84 (2), p.713-726

2011

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Thiyl Glycosylation of Olefinic Proteins: S‐Linked Glycoconjugate Synthesis

Angewandte Chemie, 2009-10, Vol.121 (42), p.7938-7942

2009

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Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometryElectronic supplementary information (ESI) available: Extended discussion on the Gaussian approximation and peak tailing, experimental details and MATLAB M-file scripts. See DOI: 10.1039/c0cc03420g

2010-12

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CD25-targeted antibody-drug conjugate depletes regulatory T cells and eliminates established syngeneic tumors via antitumor immunity

TR1801‐ADC: a highly potent cMet antibody–drug conjugate with high activity in patient‐derived xenograft models of solid tumors

Rationally Designed Short Polyisoprenol-Linked PglB Substrates for Engineered Polypeptide and Protein N‑Glycosylation

Chain-growth polyglycosylation: synthesis of linker-equipped mannosyl oligomers

An antibacterial vaccination strategy based on a glycoconjugate containing the core lipopolysaccharide tetrasaccharide Hep2Kdo2

Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

Thiyl Glycosylation of Olefinic Proteins: S-Linked Glycoconjugate Synthesis

Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305

Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography – high resolution mass spectrometry

Comparison of Pyrrolobenzodiazepine Dimer Bis-imine versus Mono-imine: DNA Interstrand Cross-linking, Cytotoxicity, Antibody-Drug Conjugate Efficacy and Toxicity

Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody–Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer

Improved Physical Stability of an Antibody–Drug Conjugate Using Host–Guest Chemistry

Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension

Strategies in the Design and Use of Synthetic "Internal Glycan" Vaccines

A Reactive Antibody Platform for One-Step Production of Antibody–Drug Conjugates through a Diels–Alder Reaction with Maleimide

Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers

Abstract 225: TR1801-ADC, an optimized anti cMet PBD ADC with high efficacy in solid tumors of the GI tract and head & neck cancer

Abstract 5736: AZD9592: An EGFR-cMET bispecific antibody-drug conjugate (ADC) targeting key oncogenic drivers in non-small-cell lung cancer (NSCLC) and beyond

MS of the six isomers of (GlcN)2(GlcNAc)2 aminoglucan tetrasaccharides (diacetylchitotetraoses): Rules of fragmentation for the sodiated molecules and application to sequence analysis of hetero-chitooligosaccharides

Comparison of pyrrolobenzodiazepine dimer bis-imine versus mono-imine: DNA interstrand cross-linking, cytotoxicity, and antibody-drug conjugate efficacy and toxicity

Potent Fluoro-oligosaccharide Probes of Adhesion in Toxoplasmosis

Abstract 1765: Discovery and first disclosure of AZD8205, a B7-H4-targeted antibody-drug conjugate utilizing a novel topoisomerase I linker-warhead

MS n of the six isomers of (GlcN) 2(GlcNAc) 2 aminoglucan tetrasaccharides (diacetylchitotetraoses): Rules of fragmentation for the sodiated molecules and application to sequence analysis of hetero-chitooligosaccharides

Thiyl Glycosylation of Olefinic Proteins: S‐Linked Glycoconjugate Synthesis

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