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Histone deacetylase inhibitors in cancer treatment

Anti-cancer drugs, 2002-01, Vol.13 (1), p.1-13

2002

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Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor α-Dependent Transcription and Promotes Proteasomal Degradation of Cyclin D1 in Human Breast Carcinoma Cell Lines

Clinical cancer research, 2004-12, Vol.10 (23), p.8094-8104

2004

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Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells

Molecular cancer, 2006-02, Vol.5 (1), p.8-8, Article 8

2006

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The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines

Molecular cancer, 2006-02, Vol.5 (1), p.7-7, Article 7

2006

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Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography

European journal of nuclear medicine and molecular imaging, 2007-09, Vol.34 (9), p.1339-1347

2007

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Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo

Clinical cancer research, 2001-04, Vol.7 (4), p.971-976

2001

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Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine -positron emission tomography imaging : Evaluation of analytical methods

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (21), p.10104-10112

2005

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In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3' -deoxy-3'-[18F]fluorothymidine positron emission tomography

Cancer research (Chicago, Ill.), 2006-08, Vol.66 (15), p.7621-7629

2006

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Structure–activity relationships of aryloxyalkanoic acid hydroxyamides as potent inhibitors of histone deacetylase

Bioorganic & medicinal chemistry letters, 2007, Vol.17 (1), p.136-141

2007

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Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3661-3663

2003

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Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2 E,4 E)-5-arylpenta-2,4-dienoic acid hydroxyamides

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2477-2481

2004

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FR-901228 Fujisawa/National Cancer Institute

Current opinion in investigational drugs (London, England : 2000), 2002-09, Vol.3 (9), p.1396

Vigushin, David M

2002

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Increased gestational age at evacuation of a complete hydatidiform mole: does it correlate with increased risk of requiring chemotherapy?

Journal of reproductive medicine, 2004-07, Vol.49 (7), p.527

2004

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The Vincotube System: a design solution to prevent the accidental administration of intrathecal vinca alkaloids

Journal of clinical oncology, 2004-03, Vol.22 (5), p.965; author reply 965-965

2004

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Targeted histone deacetylase inhibition for cancer prevention and therapy

Progress in drug research, 2005, Vol.63, p.147

2005

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Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice

Drug metabolism and disposition, 2004-10, Vol.32 (10), p.1132-1138

2004

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ICI182,780 Induces p21Waf1 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor α from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

The Journal of biological chemistry, 2005-02, Vol.280 (5), p.3185-3196

2005

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Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase

Bioorganic & medicinal chemistry letters, 2002-01, Vol.12 (2), p.255-259

2002

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Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease

The Journal of clinical investigation, 1993-04, Vol.91 (4), p.1351-1357

1993

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ICI182,780 Induces p21 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor α from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

The Journal of biological chemistry, 2005-02, Vol.280 (5), p.3185-3196

2005

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Bilateral chylothorax due to retrosternal goiter in a patient with non-Hodgkin's lymphoma

Medical oncology (Northwood, London, England), 2001-01, Vol.18 (2), p.153-158

2001

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Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer

Cancer chemotherapy and pharmacology, 1998-07, Vol.42 (2), p.111-117

1998

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ICI182,780 Induces p21Waf1 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor Î± from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

The Journal of biological chemistry, 2005-02, Vol.280 (5), p.3185

2005

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ICI182,780 Induces p21 super(Waf1) Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor alpha from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

The Journal of biological chemistry, 2005-02, Vol.280 (5), p.3185-3196

2005

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Echocardiographic assessment of cardiac involvement in systemic AL amyloidosis in relation to whole body amyloid load measured by serum amyloid P component (SAP) clearance

The American journal of cardiology, 1997-10, Vol.80 (8), p.1104-1108

1997

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Histone deacetylase inhibitors in cancer treatment

Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor α-Dependent Transcription and Promotes Proteasomal Degradation of Cyclin D1 in Human Breast Carcinoma Cell Lines

Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells

The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines

Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography

Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo

Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine -positron emission tomography imaging : Evaluation of analytical methods

In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3' -deoxy-3'-[18F]fluorothymidine positron emission tomography

Structure–activity relationships of aryloxyalkanoic acid hydroxyamides as potent inhibitors of histone deacetylase

Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I

Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2 E,4 E)-5-arylpenta-2,4-dienoic acid hydroxyamides

FR-901228 Fujisawa/National Cancer Institute

Increased gestational age at evacuation of a complete hydatidiform mole: does it correlate with increased risk of requiring chemotherapy?

The Vincotube System: a design solution to prevent the accidental administration of intrathecal vinca alkaloids

Targeted histone deacetylase inhibition for cancer prevention and therapy

Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice

ICI182,780 Induces p21Waf1 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor α from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase

Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease

ICI182,780 Induces p21 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor α from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

Bilateral chylothorax due to retrosternal goiter in a patient with non-Hodgkin's lymphoma

Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer

ICI182,780 Induces p21Waf1 Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor Î± from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

ICI182,780 Induces p21 super(Waf1) Gene Transcription through Releasing Histone Deacetylase 1 and Estrogen Receptor alpha from Sp1 Sites to Induce Cell Cycle Arrest in MCF-7 Breast Cancer Cell Line

Echocardiographic assessment of cardiac involvement in systemic AL amyloidosis in relation to whole body amyloid load measured by serum amyloid P component (SAP) clearance

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