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Designing phase I oncology dose escalation using dose–exposure–toxicity models as a complementary approach to model‐based dose–toxicity models

CPT: pharmacometrics and systems pharmacology, 2022-10, Vol.11 (10), p.1371-1381

2022

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530 A first-in-human phase I study of M6223 (TIGIT inhibitor) as monotherapy or in combination with bintrafusp alfa in patients with metastatic or locally advanced solid unresectable tumors

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A561-A561

2021

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Impact of infectious burden on extent and long-term prognosis of atherosclerosis

Circulation (New York, N.Y.), 2002-01, Vol.105 (1), p.15-21

2002

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Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC

Molecular cancer, 2012-08, Vol.11 (1), p.55-55, Article 55

2012

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Impact of infectious burden on progression of carotid atherosclerosis

Stroke (1970), 2002-11, Vol.33 (11), p.2581-2586

2002

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Interaction between gene variants of the serotonin transporter promoter region (5-HTTLPR) and catechol O-methyltransferase (COMT) in borderline personality disorder

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2009-06, Vol.150B (4), p.487-495

2009

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Cochlear Origin of Early Hearing Loss in Vestibular Schwannoma

The Laryngoscope, 2007-04, Vol.117 (4), p.680-683

2007

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Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer

PloS one, 2011-10, Vol.6 (10), p.e25750

2011

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Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

Statistics in medicine, 2022-12, Vol.41 (30), p.5789-5809

2022

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Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer

International journal of cancer, 2006-05, Vol.118 (10), p.2522-2528

2006

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Genetic and environmental influences on the fibrinolytic system: a twin study

Thrombosis and haemostasis, 2004-08, Vol.92 (2), p.344

2004

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Estimands in Oncology Early Clinical Development: Assessing the Impact of Intercurrent Events on the Dose-Toxicity Relationship

Statistics in biopharmaceutical research, 2024-01, p.1-9

2024

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Judging a Plethora of p-Values: How to Contend With the Problem of Multiple Testing - Part 10 of a Series on Evaluation of Scientific Publications

Deutsches Ärzteblatt international, 2010-01, Vol.107 (4), p.50-56

2010

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Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma

Liver transplantation, 2006-08, Vol.12 (8), p.1260-1267

2006

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In Reply

Deutsches Ärzteblatt international, 2010-06

Victor, Anja

2010

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Quantitative PK/PD Prediction of the Efficacious and Safe Dose Ranges of the LMP7 Inhibitor M3258 for Phase I Application in Relapsed/Refractory Multiple Myeloma Patients

Blood, 2019-11, Vol.134 (Supplement_1), p.5582-5582

2019

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Correspondence (reply): In Reply

Deutsches Ärzteblatt international, 2010-06, Vol.107 (23), p.417-418

Victor, Anja

2010

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Dynamic MR imaging of breast lesions: correlation with microvessel distribution pattern and histologic characteristics of prognosis

Radiology, 2006-05, Vol.239 (2), p.351

2006

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Sympathetic Vasomotor Response of the Radial Artery in Patients With Diabetic Foot Syndrome

Diabetes care, 2003-09, Vol.26 (9), p.2616-2621

2003

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Combining Adaptive Designs with Control of the False Discovery Rate - A Generalized Definition for a Global p -Value

Biometrical journal, 2007-02, Vol.49 (1), p.94-106

2007

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Prognostic factors and outcomes of patients with hepatocellular carcinoma in non-cirrhotic liver

Scandinavian journal of gastroenterology, 2012-06, Vol.47 (6), p.718-728

2012

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Abstract 5504: Second neoplasms after childhood cancer and gene expression differences in primary fibroblasts

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5504-5504

2012

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Incidence of HAV and HBV Infections and Vaccination Rates in Patients With Autoimmune Liver Diseases

The American journal of gastroenterology, 2008-01, Vol.103 (1), p.138-146

2008

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A case control study of statin and magnesium administration in patients after aneurysmal subarachnoid hemorrhage: incidence of delayed cerebral ischemia and mortality

Neurological research (New York), 2008-11, Vol.30 (9), p.893-897

2008

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Multiple Testing in Candidate Gene Situations: A Comparison of Classical, Discrete, and Resampling-Based Procedures

Statistical applications in genetics and molecular biology, 2011-11, Vol.10 (1), p.1-21

2011

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Designing phase I oncology dose escalation using dose–exposure–toxicity models as a complementary approach to model‐based dose–toxicity models

530 A first-in-human phase I study of M6223 (TIGIT inhibitor) as monotherapy or in combination with bintrafusp alfa in patients with metastatic or locally advanced solid unresectable tumors

Impact of infectious burden on extent and long-term prognosis of atherosclerosis

Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC

Impact of infectious burden on progression of carotid atherosclerosis

Interaction between gene variants of the serotonin transporter promoter region (5-HTTLPR) and catechol O-methyltransferase (COMT) in borderline personality disorder

Cochlear Origin of Early Hearing Loss in Vestibular Schwannoma

Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer

Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer

Genetic and environmental influences on the fibrinolytic system: a twin study

Estimands in Oncology Early Clinical Development: Assessing the Impact of Intercurrent Events on the Dose-Toxicity Relationship

Judging a Plethora of p-Values: How to Contend With the Problem of Multiple Testing - Part 10 of a Series on Evaluation of Scientific Publications

Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma

In Reply

Quantitative PK/PD Prediction of the Efficacious and Safe Dose Ranges of the LMP7 Inhibitor M3258 for Phase I Application in Relapsed/Refractory Multiple Myeloma Patients

Correspondence (reply): In Reply

Dynamic MR imaging of breast lesions: correlation with microvessel distribution pattern and histologic characteristics of prognosis

Sympathetic Vasomotor Response of the Radial Artery in Patients With Diabetic Foot Syndrome

Combining Adaptive Designs with Control of the False Discovery Rate - A Generalized Definition for a Global p -Value

Prognostic factors and outcomes of patients with hepatocellular carcinoma in non-cirrhotic liver

Abstract 5504: Second neoplasms after childhood cancer and gene expression differences in primary fibroblasts

Incidence of HAV and HBV Infections and Vaccination Rates in Patients With Autoimmune Liver Diseases

A case control study of statin and magnesium administration in patients after aneurysmal subarachnoid hemorrhage: incidence of delayed cerebral ischemia and mortality

Multiple Testing in Candidate Gene Situations: A Comparison of Classical, Discrete, and Resampling-Based Procedures

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