UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Phosphorothioate modified oligonucleotide–protein interactions

Nucleic acids research, 2020-06, Vol.48 (10), p.5235-5253

2020

Volltextzugriff (PDF)

Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions

PloS one, 2016-08, Vol.11 (8), p.e0161930-e0161930

2016

Volltextzugriff (PDF)

Cellular uptake and trafficking of antisense oligonucleotides

Nature biotechnology, 2017-03, Vol.35 (3), p.230-237

2017

Volltextzugriff (PDF)

Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms

PloS one, 2014-10, Vol.9 (10), p.e108625-e108625

2014

Volltextzugriff (PDF)

Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides

Nucleic acids research, 2021-09, Vol.49 (16), p.9026-9041

2021

Volltextzugriff (PDF)

The Interaction of Phosphorothioate-Containing RNA Targeted Drugs with Proteins Is a Critical Determinant of the Therapeutic Effects of These Agents

Journal of the American Chemical Society, 2020-09, Vol.142 (35), p.14754-14771

2020

Volltextzugriff (PDF)

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Nature biotechnology, 2019-06, Vol.37 (6), p.640-650

2019

Volltextzugriff (PDF)

The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA

Nucleic acids research, 2015-10, Vol.43 (18), p.8955-8963

2015

Volltextzugriff (PDF)

Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames

Nature biotechnology, 2016-08, Vol.34 (8), p.875-880

2016

Volltextzugriff (PDF)

mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway

Nucleic acids research, 2019-07, Vol.47 (13), p.6900-6916

2019

Volltextzugriff (PDF)

Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1

Nucleic acids research, 2019-11, Vol.47 (20), p.10865-10880

2019

Volltextzugriff (PDF)

Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins

Journal of the American Chemical Society, 2020-04, Vol.142 (16), p.7456-7468

2020

Volltextzugriff (PDF)

Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides

Nucleic acids research, 2018-04, Vol.46 (7), p.3579-3594

2018

Volltextzugriff (PDF)

Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon

PLoS biology, 2007-04, Vol.5 (4), p.e73-e73

2007

Volltextzugriff (PDF)

Defining the factors that contribute to on-target specificity of antisense oligonucleotides

PloS one, 2014-07, Vol.9 (7), p.e101752-e101752

2014

Volltextzugriff (PDF)

Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomes

Nucleic acids research, 2020-02, Vol.48 (3), p.1372-1391

2020

Volltextzugriff (PDF)

Acute hepatotoxicity of 2' fluoro-modified 5-10-5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins

Nucleic acids research, 2018-03, Vol.46 (5), p.2204-2217

2018

Volltextzugriff (PDF)

COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways

Nucleic acids research, 2018-11, Vol.46 (19), p.10225-10245

2018

Volltextzugriff (PDF)

Insights into innate immune activation via PS-ASO–protein–TLR9 interactions

Nucleic acids research, 2022-08, Vol.50 (14), p.8107-8126

2022

Volltextzugriff (PDF)

Binding of phosphorothioate oligonucleotides with RNase H1 can cause conformational changes in the protein and alter the interactions of RNase H1 with other proteins

Nucleic acids research, 2021-03, Vol.49 (5), p.2721-2739

2021

Volltextzugriff (PDF)

Antisense Masking of an hnRNP A1/A2 Intronic Splicing Silencer Corrects SMN2 Splicing in Transgenic Mice

American journal of human genetics, 2008-04, Vol.82 (4), p.834-848

2008

Volltextzugriff (PDF)

Interaction of ASOs with PC4 Is Highly Influenced by the Cellular Environment and ASO Chemistry

Journal of the American Chemical Society, 2020-05, Vol.142 (21), p.9661-9674, Article jacs.0c01808

2020

Volltextzugriff (PDF)

Modulation of LMNA splicing as a strategy to treat prelamin A diseases

The Journal of clinical investigation, 2016-04, Vol.126 (4), p.1592-1602

2016

Volltextzugriff (PDF)

NAT10 and DDX21 Proteins Interact with RNase H1 and Affect the Performance of Phosphorothioate Oligonucleotides

Nucleic acid therapeutics, 2022-08, Vol.32 (4), p.280-299

2022

Volltextzugriff (PDF)

Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency

PloS one, 2014-10, Vol.9 (10), p.e110615-e110615

2014

Volltextzugriff (PDF)

1 – 25 von 203

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(197)
Mit Volltextzugriff
(143)

Publikationsform

Sprache

Englisch
(203)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(2)

Menü

Weitere Dienste

Einstellungen

Phosphorothioate modified oligonucleotide–protein interactions

Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions

Cellular uptake and trafficking of antisense oligonucleotides

Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms

Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides

The Interaction of Phosphorothioate-Containing RNA Targeted Drugs with Proteins Is a Critical Determinant of the Therapeutic Effects of These Agents

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA

Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames

mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway

Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1

Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins

Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides

Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon

Defining the factors that contribute to on-target specificity of antisense oligonucleotides

Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomes

Acute hepatotoxicity of 2' fluoro-modified 5-10-5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins

COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways

Insights into innate immune activation via PS-ASO–protein–TLR9 interactions

Binding of phosphorothioate oligonucleotides with RNase H1 can cause conformational changes in the protein and alter the interactions of RNase H1 with other proteins

Antisense Masking of an hnRNP A1/A2 Intronic Splicing Silencer Corrects SMN2 Splicing in Transgenic Mice

Interaction of ASOs with PC4 Is Highly Influenced by the Cellular Environment and ASO Chemistry

Modulation of LMNA splicing as a strategy to treat prelamin A diseases

NAT10 and DDX21 Proteins Interact with RNase H1 and Affect the Performance of Phosphorothioate Oligonucleotides

Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency

Suchergebnisse filtern