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A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry

PloS one, 2014-12, Vol.9 (12), p.e113918-e113918

2014

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Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis

PLoS pathogens, 2011-02, Vol.7 (2), p.e1001286-e1001286

2011

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Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

Journal of lipid research, 2018-08, Vol.59 (8), p.1461-1471

2018

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Phosphatidylinositol 3-Phosphate, an Essential Lipid in Plasmodium, Localizes to the Food Vacuole Membrane and the Apicoplast

Eukaryotic Cell, 2010-10, Vol.9 (10), p.1519-1530

2010

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Chemotherapy against babesiosis

Veterinary parasitology, 2006-05, Vol.138 (1), p.147-160

2006

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High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8), p.00352-17

2017

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Glycerophospholipid acquisition in Plasmodium – A puzzling assembly of biosynthetic pathways

International journal for parasitology, 2010-10, Vol.40 (12), p.1347-1365

2010

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Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes

PloS one, 2012-05, Vol.7 (5), p.e37378-e37378

2012

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Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2203-2207

2019

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Reliability of Antimalarial Sensitivity Tests Depends on Drug Mechanisms of Action

Journal of Clinical Microbiology, 2010-05, Vol.48 (5), p.1651-1660

2010

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Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways

BMC systems biology, 2013-11, Vol.7 (1), p.123-123

2013

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The Kennedy phospholipid biosynthesis pathways are refractory to genetic disruption in Plasmodium berghei and therefore appear essential in blood stages

Molecular and biochemical parasitology, 2010-10, Vol.173 (2), p.69-80

2010

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SC83288 is a clinical development candidate for the treatment of severe malaria

Nature communications, 2017-01, Vol.8 (1), p.14193-17, Article 14193

2017

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Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways[S]

Journal of lipid research, 2010-01, Vol.51 (1), p.81-96

2010

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A novel live-dead staining methodology to study malaria parasite viability

Malaria journal, 2013-06, Vol.12 (1), p.190-190, Article 190

2013

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Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei

Molecular and biochemical parasitology, 2009-12, Vol.168 (2), p.172-176

2009

Volltextzugriff (PDF)

ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

PLoS pathogens, 2007-02, Vol.3 (2), p.e14-e14

2007

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Disulfide Prodrugs of Albitiazolium (T3/SAR97276): Synthesis and Biological Activities

Journal of medicinal chemistry, 2012-05, Vol.55 (10), p.4619-4628

2012

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Targeting the lipid metabolic pathways for the treatment of malaria

Drug development research, 2010-02, Vol.71 (1), p.44-55

2010

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The rhoptry neck protein RON4 relocalizes at the moving junction during Toxoplasma gondii invasion

Cellular microbiology, 2005-12, Vol.7 (12), p.1823-1833

2005

Volltextzugriff (PDF)

Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria

Nature communications, 2017-04, Vol.8 (1), p.15273-15273, Article 15273

2017

Volltextzugriff (PDF)

New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial

Antimicrobial agents and chemotherapy, 2014-09, Vol.58 (9), p.5519-5527

2014

Volltextzugriff (PDF)

Choline analogues in malaria chemotherapy

Current pharmaceutical design, 2012, Vol.18 (24), p.3454

2012

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Synergistic role of micronemal proteins in Toxoplasma gondii virulence

The Journal of experimental medicine, 2005-02, Vol.201 (3), p.453-463

2005

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Prodrugs of Bisthiazolium Salts Are Orally Potent Antimalarials

Proceedings of the National Academy of Sciences - PNAS, 2004-10, Vol.101 (43), p.15458-15463

2004

Volltextzugriff (PDF)

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A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry

Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

Phosphatidylinositol 3-Phosphate, an Essential Lipid in Plasmodium, Localizes to the Food Vacuole Membrane and the Apicoplast

Chemotherapy against babesiosis

High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death

Glycerophospholipid acquisition in Plasmodium – A puzzling assembly of biosynthetic pathways

Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials

Reliability of Antimalarial Sensitivity Tests Depends on Drug Mechanisms of Action

Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways

The Kennedy phospholipid biosynthesis pathways are refractory to genetic disruption in Plasmodium berghei and therefore appear essential in blood stages

SC83288 is a clinical development candidate for the treatment of severe malaria

Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways[S]

A novel live-dead staining methodology to study malaria parasite viability

Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei

ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

Disulfide Prodrugs of Albitiazolium (T3/SAR97276): Synthesis and Biological Activities

Targeting the lipid metabolic pathways for the treatment of malaria

The rhoptry neck protein RON4 relocalizes at the moving junction during Toxoplasma gondii invasion

Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria

New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial

Choline analogues in malaria chemotherapy

Synergistic role of micronemal proteins in Toxoplasma gondii virulence

Prodrugs of Bisthiazolium Salts Are Orally Potent Antimalarials

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