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Membrane rafts in Alzheimer's disease beta-amyloid production

Biochimica et biophysica acta, 2010-08, Vol.1801 (8), p.860-867

2010

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Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

Molecular neurodegeneration, 2014-01, Vol.9 (1), p.1-1, Article 1

2014

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A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1552-1563

2013

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Pathological and physiological functions of presenilins

Molecular neurodegeneration, 2006-06, Vol.1 (1), p.4-4, Article 4

2006

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Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

Neurology, 2006-01, Vol.66 (2 Suppl 1), p.S69

2006

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Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism

Molecular neurodegeneration, 2007-02, Vol.2 (1), p.4-4, Article 4

2007

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Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.E9665-E9674

2017

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Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.3793-3803

2009

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Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

The Journal of biological chemistry, 2004-10, Vol.279 (43), p.44945-44954

2004

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Localization and regional distribution of p23/TMP21 in the brain

Neurobiology of disease, 2008-10, Vol.32 (1), p.37-49

2008

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Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Molecular neurodegeneration, 2011-12, Vol.6 (1), p.87-87, Article 87

2011

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Ca2+ Influx through Store-operated Ca2+ Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

The Journal of biological chemistry, 2013-09, Vol.288 (37), p.26955-26966

2013

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Mechanisms of Disease: new therapeutic strategies for Alzheimer's disease-targeting APP processing in lipid rafts

Nature Clinical Practice Neurology, 2007-07, Vol.3 (7), p.374-382

2007

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Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain

The Journal of neuroscience, 2012-02, Vol.32 (5), p.1714-1729

2012

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Loss of Cleavage at β′-Site Contributes to Apparent Increase in β-Amyloid Peptide (Aβ) Secretion by β-Secretase (BACE1)-Glycosylphosphatidylinositol (GPI) Processing of Amyloid Precursor Protein

The Journal of biological chemistry, 2011-07, Vol.286 (29), p.26166-26177

2011

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Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

The Journal of biological chemistry, 2010-12, Vol.285 (49), p.38042-38052

2010

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S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1

The Journal of biological chemistry, 2009-01, Vol.284 (3), p.1373-1384

2009

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Nicastrin Is Critical for Stability and Trafficking but Not Association of Other Presenilin/γ-Secretase Components

The Journal of biological chemistry, 2005-04, Vol.280 (17), p.17020-17026

2005

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Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19489-19498

2008

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Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease

Molecular neurodegeneration, 2012-02, Vol.7 (Suppl 1), p.L2-L2

2012

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P3-337: S-palmitoylation targets BACE-1 to lipid rafts

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T620-T620

2008

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O2-03-01: Exploring β-secretase activity in lipid raft microdomains

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T135-T135

2008

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P3-324: Characterization of S-palmitoylation in gamma-secretase subunits

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T616-T617

2008

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Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of g-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

The Journal of biological chemistry, 2010-12, Vol.285 (49), p.38042-38052

2010

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Regulation of dynamic BACE1 trafficking in neurons

Molecular neurodegeneration, 2013-09, Vol.8 (S1), p.O8-O8, Article O8

2013

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Membrane rafts in Alzheimer's disease beta-amyloid production

Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase

A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Pathological and physiological functions of presenilins

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism

Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

Localization and regional distribution of p23/TMP21 in the brain

Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Ca2+ Influx through Store-operated Ca2+ Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

Mechanisms of Disease: new therapeutic strategies for Alzheimer's disease-targeting APP processing in lipid rafts

Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain

Loss of Cleavage at β′-Site Contributes to Apparent Increase in β-Amyloid Peptide (Aβ) Secretion by β-Secretase (BACE1)-Glycosylphosphatidylinositol (GPI) Processing of Amyloid Precursor Protein

Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1

Nicastrin Is Critical for Stability and Trafficking but Not Association of Other Presenilin/γ-Secretase Components

Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ

Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease

P3-337: S-palmitoylation targets BACE-1 to lipid rafts

O2-03-01: Exploring β-secretase activity in lipid raft microdomains

P3-324: Characterization of S-palmitoylation in gamma-secretase subunits

Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of g-Secretase Activity toward Amyloid Precursor Protein and Other Substrates

Regulation of dynamic BACE1 trafficking in neurons

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