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Bioluminescent RAPPID Sensors for the Single-Step Detection of Soluble Axl and Multiplex Analysis of Cell Surface Cancer Biomarkers

Analytical chemistry (Washington), 2022-05, Vol.94 (17), p.6548-6556

2022

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Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

Glia, 2010-09, Vol.58 (12), p.1465-1476

2010

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Human Cytomegalovirus-Encoded Chemokine Receptor US28 Promotes Tumorigenesis

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (35), p.13068-13073

2006

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Functionally biased modulation of A3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

Biochemical pharmacology, 2011-09, Vol.82 (6), p.658-668

2011

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An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation

Oncoimmunology, 2022, Vol.11 (1), p.2030135-2030135

2022

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DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity

Journal for immunotherapy of cancer, 2022-06, Vol.10 (6), p.e004322

2022

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Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28

The Journal of biological chemistry, 2001-01, Vol.276 (2), p.1133-1137

2001

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Sphingosine-1-phosphate receptors: Zooming in on ligand-induced intracellular trafficking and its functional implications

Molecules and Cells, 2010, 29(2), , pp.99-104

2010

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The Epstein-Barr Virus BILF1 Gene Encodes a G Protein-Coupled Receptor That Inhibits Phosphorylation of RNA-Dependent Protein Kinase

Journal of Virology, 2005-01, Vol.79 (1), p.441-449

2005

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863 In vitro and in vivo studies establish DuoBody®-CD3xB7H4 as a novel drug candidate for the treatment of solid cancers

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A904-A904

2021

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Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors

The Journal of pharmacology and experimental therapeutics, 2008-05, Vol.325 (2), p.544-555

2008

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Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via Gi and Phospholipase C-Dependent Signaling Pathways

Journal of Virology, 2002-02, Vol.76 (4), p.1744-1752

2002

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Constitutive Signaling of the Human Cytomegalovirus-encoded Receptor UL33 Differs from That of Its Rat Cytomegalovirus Homolog R33 by Promiscuous Activation of G Proteins of the Gq, Gi, and Gs Classes

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.50010-50023

2003

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Helix 8 of the Viral Chemokine Receptor ORF74 Directs Chemokine Binding

The Journal of biological chemistry, 2006-11, Vol.281 (46), p.35327-35335

2006

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Chemokine-Directed Trafficking of Receptor Stimulus to Different G Proteins: Selective Inducible and Constitutive Signaling by Human Herpesvirus 6-Encoded Chemokine Receptor U51

Molecular pharmacology, 2006-03, Vol.69 (3), p.888-898

2006

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Differential Activation of Murine Herpesvirus 68- and Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORF74 G Protein-Coupled Receptors by Human and Murine Chemokines

Journal of Virology, 2004-04, Vol.78 (7), p.3343-3351

2004

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Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

Cancer discovery, 2022-05, Vol.12 (5), p.1248-1265

2022

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Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

Biochemical pharmacology, 2011-09, Vol.82 (6), p.658

2011

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Functional selectivity of adenosine receptor ligands

Purinergic signalling, 2011-06, Vol.7 (2), p.171-192

2011

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Neutralizing Nanobodies Targeting Diverse Chemokines Effectively Inhibit Chemokine Function

The Journal of biological chemistry, 2013-08, Vol.288 (35), p.25173-25182

2013

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Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity

EBioMedicine, 2023-07, Vol.93, p.104663-104663, Article 104663

2023

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Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells

Stem cells and development, 2014-08, Vol.23 (16), p.1959-1974

2014

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Identity of Adenylyl Cyclase Isoform Determines the Rate of Cell Cycle Progression in NIH 3T3 Cells

Proceedings of the National Academy of Sciences - PNAS, 1998-12, Vol.95 (25), p.15084-15089

1998

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Functional selectivity of adenosine A1 receptor ligands?

Purinergic signalling, 2013-03, Vol.9 (1), p.91-100

2013

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Bioluminescent RAPPID Sensors for the Single-Step Detection of Soluble Axl and Multiplex Analysis of Cell Surface Cancer Biomarkers

Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

Human Cytomegalovirus-Encoded Chemokine Receptor US28 Promotes Tumorigenesis

Functionally biased modulation of A3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation

DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity

Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28

Sphingosine-1-phosphate receptors: Zooming in on ligand-induced intracellular trafficking and its functional implications

The Epstein-Barr Virus BILF1 Gene Encodes a G Protein-Coupled Receptor That Inhibits Phosphorylation of RNA-Dependent Protein Kinase

863 In vitro and in vivo studies establish DuoBody®-CD3xB7H4 as a novel drug candidate for the treatment of solid cancers

Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors

Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via Gi and Phospholipase C-Dependent Signaling Pathways

Constitutive Signaling of the Human Cytomegalovirus-encoded Receptor UL33 Differs from That of Its Rat Cytomegalovirus Homolog R33 by Promiscuous Activation of G Proteins of the Gq, Gi, and Gs Classes

Helix 8 of the Viral Chemokine Receptor ORF74 Directs Chemokine Binding

Chemokine-Directed Trafficking of Receptor Stimulus to Different G Proteins: Selective Inducible and Constitutive Signaling by Human Herpesvirus 6-Encoded Chemokine Receptor U51

Differential Activation of Murine Herpesvirus 68- and Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORF74 G Protein-Coupled Receptors by Human and Murine Chemokines

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors

Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers

Functional selectivity of adenosine receptor ligands

Neutralizing Nanobodies Targeting Diverse Chemokines Effectively Inhibit Chemokine Function

Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity

Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells

Identity of Adenylyl Cyclase Isoform Determines the Rate of Cell Cycle Progression in NIH 3T3 Cells

Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activityResearch in context

Functional selectivity of adenosine A1 receptor ligands?

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