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PDE5 inhibitors and their applications

Current medicinal chemistry, 2010-08, Vol.17 (24), p.2564

2010

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Selective ACAT inhibitors as promising antihyperlipidemic, antiathero-sclerotic and anti-Alzheimer drugs

Mini reviews in medicinal chemistry, 2003, Vol.3 (6), p.576

2003

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[(3-Chlorophenyl)piperazinylpropyl]pyridazinones and Analogues as Potent Antinociceptive Agents

Journal of medicinal chemistry, 2003-03, Vol.46 (6), p.1055-1059

2003

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4-Amino-5-substituted-3(2H)-pyridazinones as Orally Active Antinociceptive Agents: Synthesis and Studies on the Mechanism of Action

Journal of medicinal chemistry, 2007-08, Vol.50 (16), p.3945-3953

2007

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New pyrazolo[1′,5′:1,6]pyrimido[4,5- d]pyridazin-4(3 H)-ones as potent and selective PDE5 inhibitors

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2381-2384

2005

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Isoxazolo[3,4- d]pyridazinones and analogues as Leishmania mexicana PDE inhibitors

Farmaco (Società chimica italiana : 1989), 2002-02, Vol.57 (2), p.89-96

2002

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Synthesis and Evaluation of Novel Pyrrolo[2,3-d] and Thieno[2,3-d]Pyridazinones as in Vitro Antiproliferative Agents

Acta chimica Slovenica, 2009-01, Vol.56 (3)

2009

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Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site

Naunyn-Schmiedeberg's archives of pharmacology, 2002-04, Vol.365 (4), p.284-289

2002

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Synthesis and Evaluation of Some Pyrazolo[3,4-d]pyridazinones and Analogues as PDE 5 Inhibitors Potentially Useful as Peripheral Vasodilator Agents

Journal of enzyme inhibition and medicinal chemistry, 2002-01, Vol.17 (4), p.227-233

2002

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Novel 3-Arylamino- and 3-Cycloalkylamino-5, 6-diphenyl-pyridazines Active as ACAT Inhibitors

Archiv der Pharmazie (Weinheim), 2003-01, Vol.335 (11-12), p.563-566

2003

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New Synthesis of Differently Fused Pyridazinoquinolines

Synlett, 1999-09, Vol.1999 (9), p.1453-1455

1999

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CLIMATE-INDUCED CONSERVATION RISKS OF HISTORIC REINFORCED CONCRETE BUILDINGS: PRELIMINARY RESULTS FROM LITERATURE REVIEW

International archives of the photogrammetry, remote sensing and spatial information sciences., 2023, Vol.XLVIII-M-2-2023, p.227-234

2023

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Pédagogie et droits de l’homme

Véronique Champeil-Desplats (dir.)

2014

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Cutting Edge: Predictable TCR Antigen Recognition Based on Peptide Scans Leads to the Identification of Agonist Ligands with No Sequence Homology

The Journal of immunology (1950), 1998-04, Vol.160 (8), p.3631-3636

1998

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Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population

Neuroscience letters, 2002-08, Vol.328 (3), p.325-327

2002

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Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency

The Journal of immunology (1950), 2000-01, Vol.164 (2), p.861-871

2000

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Symptomatic unruptured capillary telangiectasia of the brain stem: report of three cases and review of the literature

Journal of neurology, neurosurgery and psychiatry, 2001-09, Vol.71 (3), p.390-393

2001

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IL-7-enhanced T-cell response to myelin proteins in multiple sclerosis

Journal of neuroimmunology, 2001-12, Vol.121 (1), p.111-119

2001

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Palmitoyl Derivatives of GpMBP Epitopes: T-Cell Response and Peptidases Susceptibility

Journal of medicinal chemistry, 2001-10, Vol.44 (21), p.3504-3510

2001

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Decrypting the spectrum of antigen-specific T-cell responses: the avidity repertoire of MBP-specific T-cells

Journal of neuroscience research, 2000-01, Vol.59 (1), p.86-93

2000

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Short-term evolution of autoreactive T cell repertoire in multiple sclerosis

Journal of neuroscience research, 2001-11, Vol.66 (3), p.517-524

2001

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T cell response to myelin basic protein in the context of the multiple sclerosis-associated HLA-DR15 haplotype: peptide binding, immunodominance and effector functions of T cells

Journal of neuroimmunology, 1997-08, Vol.77 (2), p.195-203

1997

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Growth Properties and Growth Factor Responsiveness in Skin Fibroblasts from Centenarians

Biochemical and biophysical research communications, 1998-03, Vol.244 (3), p.912-916

1998

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Transforming growth factor-β1 inhibits the proliferation of rat astrocytes induced by serum and growth factors

Journal of neuroscience research, 1995-01, Vol.40 (1), p.127-133

1995

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C-Fos/C-Jun Expression and AP-1 Activation in Skin Fibroblasts from Centenarians

Biochemical and biophysical research communications, 1996-09, Vol.226 (2), p.517-523

1996

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PDE5 inhibitors and their applications

Selective ACAT inhibitors as promising antihyperlipidemic, antiathero-sclerotic and anti-Alzheimer drugs

[(3-Chlorophenyl)piperazinylpropyl]pyridazinones and Analogues as Potent Antinociceptive Agents

4-Amino-5-substituted-3(2H)-pyridazinones as Orally Active Antinociceptive Agents: Synthesis and Studies on the Mechanism of Action

New pyrazolo[1′,5′:1,6]pyrimido[4,5- d]pyridazin-4(3 H)-ones as potent and selective PDE5 inhibitors

Isoxazolo[3,4- d]pyridazinones and analogues as Leishmania mexicana PDE inhibitors

Synthesis and Evaluation of Novel Pyrrolo[2,3-d] and Thieno[2,3-d]Pyridazinones as in Vitro Antiproliferative Agents

Airway relaxant and anti-inflammatory properties of a PDE4 inhibitor with low affinity for the high-affinity rolipram binding site

Synthesis and Evaluation of Some Pyrazolo[3,4-d]pyridazinones and Analogues as PDE 5 Inhibitors Potentially Useful as Peripheral Vasodilator Agents

Novel 3-Arylamino- and 3-Cycloalkylamino-5, 6-diphenyl-pyridazines Active as ACAT Inhibitors

New Synthesis of Differently Fused Pyridazinoquinolines

CLIMATE-INDUCED CONSERVATION RISKS OF HISTORIC REINFORCED CONCRETE BUILDINGS: PRELIMINARY RESULTS FROM LITERATURE REVIEW

Pédagogie et droits de l’homme

Cutting Edge: Predictable TCR Antigen Recognition Based on Peptide Scans Leads to the Identification of Agonist Ligands with No Sequence Homology

Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population

Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency

Symptomatic unruptured capillary telangiectasia of the brain stem: report of three cases and review of the literature

IL-7-enhanced T-cell response to myelin proteins in multiple sclerosis

Palmitoyl Derivatives of GpMBP Epitopes: T-Cell Response and Peptidases Susceptibility

Decrypting the spectrum of antigen-specific T-cell responses: the avidity repertoire of MBP-specific T-cells

Short-term evolution of autoreactive T cell repertoire in multiple sclerosis

T cell response to myelin basic protein in the context of the multiple sclerosis-associated HLA-DR15 haplotype: peptide binding, immunodominance and effector functions of T cells

Growth Properties and Growth Factor Responsiveness in Skin Fibroblasts from Centenarians

Transforming growth factor-β1 inhibits the proliferation of rat astrocytes induced by serum and growth factors

C-Fos/C-Jun Expression and AP-1 Activation in Skin Fibroblasts from Centenarians

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