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Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies

The Journal of clinical investigation, 2017-10, Vol.127 (10), p.3657-3674

2017

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells

iScience, 2022-04, Vol.25 (4), p.104004-104004, Article 104004

2022

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B‐cell acute lymphoblastic leukemia with iAMP21 in a patient with Down syndrome due to a constitutional isodicentric chromosome 21

American journal of medical genetics. Part A, 2022-08, Vol.188 (8), p.2325-2330

2022

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A pathogenic relationship between a regulator of the actin cytoskeleton and serum response factor

Genetics (Austin), 2010-09, Vol.186 (1), p.147-157

2010

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Defects in actin dynamics lead to an autoinflammatory condition through the upregulation of CXCL5

PloS one, 2008-07, Vol.3 (7), p.e2701-e2701

2008

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Remethylation of Dnmt3a −/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (6), p.3123-3134

2020

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PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia

The Journal of clinical investigation, 2016-01, Vol.126 (1), p.85-98

2016

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Notch signaling in acute promyelocytic leukemia

Leukemia, 2013-07, Vol.27 (7), p.1548-1557

2013

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Serum response factor is essential for the proper development of skin epithelium

Mammalian genome, 2010-02, Vol.21 (1-2), p.64-76

2010

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Effect of destrin mutations on the gene expression profile in vivo

Physiological genomics, 2008-06, Vol.34 (1), p.9-21

2008

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Serum response factor: positive and negative regulation of an epithelial gene expression network in the destrin mutant cornea

Physiological genomics, 2014-04, Vol.46 (8), p.277-289

2014

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Differences in corneal phenotypes between destrin mutants are due to allelic difference and modified by genetic background

Molecular vision, 2012-03, Vol.18, p.606-616

2012

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Myeloproliferative Disease and Myeloid Leukemia in Dnmt3a Haploinsufficient Mice

Blood, 2014-12, Vol.124 (21), p.890-890

2014

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DNMT3A R882H Overexpression Leads To Hematopoietic and Skin Alterations In Transgenic Mice

Blood, 2013-11, Vol.122 (21), p.479-479

2013

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DNMT3A R882H Overexpression Acts in a Dominant Negative Manner to Cause DNA Hypomethylation and Increased Susceptibility to Hematopoietic Malignancies in Transgenic Mice

Blood, 2014-12, Vol.124 (21), p.609-609

2014

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Dnmt3a is Required For Aberrant Self-Renewal Driven by PML-RARA

Blood, 2013-11, Vol.122 (21), p.477-477

2013

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Whole Genome Bisulfite Sequencing of Purified Mouse Promyelocytes Reveals Differentially Methylated Regions in Cells Expressing PML-Rara

Blood, 2014-12, Vol.124 (21), p.3531-3531

2014

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Activation of Notch Signaling Is An Early Event in the Development of PML-Rara-Induced Acute Promyelocytic Leukemia (APL)

Blood, 2011-11, Vol.118 (21), p.2468-2468

2011

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Elucidating the mechanisms underlying epithelial abnormalities and neovascularization in vivo

Verdoni, Angela M

2010

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Dnmt3a Inactivation Leads to Slow DNA Methylation Loss in Murine Hematopoietic Cells In Vivo

Blood, 2021-11, Vol.138 (Supplement 1), p.1087-1087

2021

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Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies

Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells

B‐cell acute lymphoblastic leukemia with iAMP21 in a patient with Down syndrome due to a constitutional isodicentric chromosome 21

A pathogenic relationship between a regulator of the actin cytoskeleton and serum response factor

Defects in actin dynamics lead to an autoinflammatory condition through the upregulation of CXCL5

Remethylation of Dnmt3a −/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia

Notch signaling in acute promyelocytic leukemia

Serum response factor is essential for the proper development of skin epithelium

Effect of destrin mutations on the gene expression profile in vivo

Serum response factor: positive and negative regulation of an epithelial gene expression network in the destrin mutant cornea

Differences in corneal phenotypes between destrin mutants are due to allelic difference and modified by genetic background

Myeloproliferative Disease and Myeloid Leukemia in Dnmt3a Haploinsufficient Mice

DNMT3A R882H Overexpression Leads To Hematopoietic and Skin Alterations In Transgenic Mice

DNMT3A R882H Overexpression Acts in a Dominant Negative Manner to Cause DNA Hypomethylation and Increased Susceptibility to Hematopoietic Malignancies in Transgenic Mice

Dnmt3a is Required For Aberrant Self-Renewal Driven by PML-RARA

Whole Genome Bisulfite Sequencing of Purified Mouse Promyelocytes Reveals Differentially Methylated Regions in Cells Expressing PML-Rara

Activation of Notch Signaling Is An Early Event in the Development of PML-Rara-Induced Acute Promyelocytic Leukemia (APL)

Elucidating the mechanisms underlying epithelial abnormalities and neovascularization in vivo

Dnmt3a Inactivation Leads to Slow DNA Methylation Loss in Murine Hematopoietic Cells In Vivo

Early anakinra treatment improves cardiac outcome of multisystem inflammatory syndrome in children, regardless of disease severity

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