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Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Blood, 2013-02, Vol.121 (8), p.1276-1284

2013

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Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

Blood, 2014-01, Vol.123 (3), p.377-390

2014

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Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (23), p.7009-7021

2013

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Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction

PloS one, 2018-04, Vol.13 (4), p.e0196455-e0196455

2018

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SARS-CoV-2 severity in African Americans - A role for Duffy Null?

Haematologica (Roma), 2020-12, Vol.105 (12), p.2892

2020

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Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia

PloS one, 2018-10, Vol.13 (10), p.e0205194

2018

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First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

Blood advances, 2019-07, Vol.3 (13), p.1970-1980

2019

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A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease

Haematologica (Roma), 2020-03, Vol.105 (3), p.623

2020

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Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins

American journal of physiology. Renal physiology, 2018-05, Vol.314 (5), p.F906-F914

2018

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Red cells, hemoglobin, heme, iron, and atherogenesis

Arteriosclerosis, thrombosis, and vascular biology, 2010-07, Vol.30 (7), p.1347

2010

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Therapeutic strategies for sickle cell disease: towards a multi-agent approach

Nature reviews. Drug discovery, 2019-02, Vol.18 (2), p.139-158

2019

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Identification of a Heme Activation Site on the MD-2/TLR4 Complex

Frontiers in immunology, 2020-06, Vol.11, p.1370-1370

2020

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Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease

Frontiers in immunology, 2021-01, Vol.11, p.613278-613278

2021

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Blood–Nanoparticle Interactions and in Vivo Biodistribution: Impact of Surface PEG and Ligand Properties

Molecular pharmaceutics, 2012-08, Vol.9 (8), p.2146-2155

2012

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Pro-oxidant and cytotoxic effects of circulating heme

Blood, 2002-08, Vol.100 (3), p.879-887

2002

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Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells

Frontiers in immunology, 2021-03, Vol.12, p.632709-632709

2021

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Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease

Molecular medicine (Cambridge, Mass.), 2016-01, Vol.22 (1), p.437-451

2016

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Heme, heme oxygenase, and ferritin: how the vascular endothelium survives (and dies) in an iron-rich environment

Antioxidants & redox signaling, 2007-12, Vol.9 (12), p.2119

2007

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Endothelial cell provenance: an unclear role in transplant medicine

Frontiers in transplantation, 2023-04, Vol.2, p.1130941

2023

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Correction of Fanconi Anemia Mutations Using Digital Genome Engineering

International journal of molecular sciences, 2022-07, Vol.23 (15), p.8416

2022

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The multifaceted role of ischemia/reperfusion in sickle cell anemia

The Journal of clinical investigation, 2020-03, Vol.130 (3), p.1062-1072

2020

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The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease

Frontiers in medicine, 2023-04, Vol.10, p.1101501-1101501

2023

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Sudden Onset Iron Overload Cardiomyopathy After Liver Transplantation

JIM - high impact case reports, 2023-01, Vol.11, p.23247096231159812-23247096231159812

2023

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Romidepsin-associated cardiac toxicity and ECG changes: A case report and review of the literature

Journal of oncology pharmacy practice, 2018-01, Vol.24 (1), p.56-62

2018

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Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction

SARS-CoV-2 severity in African Americans - A role for Duffy Null?

Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease

Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins

Red cells, hemoglobin, heme, iron, and atherogenesis

Therapeutic strategies for sickle cell disease: towards a multi-agent approach

Identification of a Heme Activation Site on the MD-2/TLR4 Complex

Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease

Blood–Nanoparticle Interactions and in Vivo Biodistribution: Impact of Surface PEG and Ligand Properties

Pro-oxidant and cytotoxic effects of circulating heme

Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells

Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease

Heme, heme oxygenase, and ferritin: how the vascular endothelium survives (and dies) in an iron-rich environment

Endothelial cell provenance: an unclear role in transplant medicine

Correction of Fanconi Anemia Mutations Using Digital Genome Engineering

The multifaceted role of ischemia/reperfusion in sickle cell anemia

Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence

The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease

Sudden Onset Iron Overload Cardiomyopathy After Liver Transplantation

Romidepsin-associated cardiac toxicity and ECG changes: A case report and review of the literature

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